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1.	Ivert, L, et al. (author) Mobile digital dermatoscopy in vivo for the diagnosis of melanoma 2017 In: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. - 0926-9959. ; 31, s. 59-59 Conference paper (other academic/artistic)
2.	Sartorius, K, et al. (author) Interobserver variability of clinical scores in hidradenitis suppurativa is low 2010 In: The British journal of dermatology. - : Oxford University Press (OUP). - 1365-2133 .- 0007-0963. ; 162:6, s. 1261-1268 Journal article (peer-reviewed)
3.	Sonkoly, E, et al. (author) MicroRNA-203 functions as a tumor suppressor in basal cell carcinoma. 2012 In: Oncogenesis. - : Springer Science and Business Media LLC. - 2157-9024. ; 1 Journal article (peer-reviewed)abstract Basal cell carcinoma (BCC) of the skin represents the most common malignancy in humans. MicroRNAs (miRNAs), small regulatory RNAs with pleiotropic function, are commonly misregulated in cancer. Here we identify miR-203, a miRNA abundantly and preferentially expressed in skin, to be downregulated in BCCs. We show that activation of the Hedgehog (HH) pathway, critically involved in the pathogenesis of BCCs, as well as the EGFR/MEK/ERK/c-JUN signaling pathway suppresses miR-203. We identify c-JUN, a key effector of the HH pathway, as a novel direct target for miR-203 in vivo. Further supporting the role of miR-203 as a tumor suppressor, in vivo delivery of miR-203 mimics in a BCC mouse model results in the reduction of tumor growth. Our results identify a regulatory circuit involving miR-203 and c-JUN, which provides functional control over basal cell proliferation and differentiation. We propose that miR-203 functions as a 'bona fide' tumor suppressor in BCC, whose suppressed expression contributes to oncogenic transformation via derepression of multiple stemness- and proliferation-related genes, and its overexpression could be of therapeutic value.
4.	Sonkoly, E, et al. (author) MiR-203 functions as a tumor suppressor microRNA in basal cell carcinoma 2011 In: JOURNAL OF INVESTIGATIVE DERMATOLOGY. - 0022-202X. ; 131, s. S20-S20 Conference paper (other academic/artistic)
5.	Gronberg, A, et al. (author) Antioxidants protect keratinocytes against M. ulcerans mycolactone cytotoxicity 2010 In: PloS one. - : Public Library of Science (PLoS). - 1932-6203. ; 5:11, s. e13839- Journal article (peer-reviewed)
6.	Hehenberger, K, et al. (author) Increased lactate production in chronic diabetic wound fibroblasts showing decreased cellular proliferation 1997 In: DIABETOLOGIA. - 0012-186X. ; 40, s. 1833-1833 Conference paper (other academic/artistic)
7.	Lonndahl, L, et al. (author) The substance P antagonist apripetant shows no additive effect compared to standardized topical treatment alone, in atopic dermatitis patients 2015 In: JOURNAL OF INVESTIGATIVE DERMATOLOGY. - 0022-202X. ; 135, s. S14-S14 Conference paper (other academic/artistic)
8.	Mallbris, L, et al. (author) Injury downregulates the expression of the human cathelicidin protein hCAP18/LL-37 in atopic dermatitis 2010 In: Experimental dermatology. - : Wiley. - 1600-0625 .- 0906-6705. ; 19:5, s. 442-449 Journal article (peer-reviewed)
9.	Stahle, M, et al. (author) Vitamin D treatment upregulites the antimicrobial protein hCAP18/LL-37 in atopic dermatitis 2008 In: JOURNAL OF INVESTIGATIVE DERMATOLOGY. - 0022-202X. ; 128, s. S9-S9 Conference paper (other academic/artistic)
10.	Xu, N, et al. (author) Identification of a distinct microRNAome and tumor suppressive role of microRNA-125b in cutaneous squamous cell carcinoma 2013 In: JOURNAL OF INVESTIGATIVE DERMATOLOGY. - 0022-202X. ; 133, s. S58-S58 Conference paper (other academic/artistic)

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Type of publication: conference paper (6); journal article (4)

Type of content: other academic/artistic (6); peer-reviewed (4)

Author/Editor: Heilborn, J (10); Stahle, M (5); Xu, N. (3); Harada, M. (3); Grander, D (3); Homey, B (3); show more...; Sonkoly, E (3); Pivarcsi, A (3); Wei, T (3); Meisgen, F (3); Brodin, P (2); Kasper, M (2); Granath, F. (2); Loven, J (2); Arsenian-Henriksson, ... (2); Lapins, J. (2); Nilsson, MF (2); Carlén, L (2); Mallbris, L (2); Jaks, V (2); Killasli, H (2); Shimokawa, T (2); Zhang, L. (1); Britton, S. (1); Nordlind, K (1); Holst, M (1); Lonndahl, L (1); Zou, L. (1); Bradley, M (1); Brismar, K (1); Bergh, K. (1); Hansson, A (1); Akuffo, H (1); Hall, M. (1); Alderling, M (1); Angeby, K (1); Emtestam, L (1); Gronberg, A (1); Hedblad, MA (1); Ståhle, M (1); Jemec, GBE (1); Sartorius, K (1); Ivert, L (1); Zettergren, L (1); Small, PL (1); Gumulka, M (1); HEHENBERGER, K (1); Stichenwirth, M (1); Zaphiropoulos, P G (1); Wei, TL (1); show less...

University: Karolinska Institutet (10); Uppsala University (1)

Language: English (10)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

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