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Sökning: WFRF:(Mahony E.)

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1.
  • Shulevski, A., et al. (författare)
  • The peculiar radio galaxy 4C 35.06 : a case for recurrent AGN activity?
  • 2015
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 579, s. 1-10
  • Tidskriftsartikel (refereegranskat)abstract
    • Using observations obtained with the LOw Fequency ARray (LOFAR), the Westerbork Synthesis Radio Telescope (WSRT) and archival Very Large Array (VLA) data, we have traced the radio emission to large scales in the complex source 4C 35.06 located in the core of the galaxy cluster Abell 407. At higher spatial resolution (~ 4″), the source was known to have two inner radio lobes spanning 31 kpc and a diffuse, low-brightness extension running parallel to them, offset by about 11 kpc (in projection). At 62 MHz, we detect the radio emission of this structure extending out to 210 kpc. At 1.4 GHz and intermediate spatial resolution (~ 30″), the structure appears to have a helical morphology. We have derived the characteristics of the radio spectral index across the source. We show that the source morphology is most likely the result of at least two episodes of AGN activity separated by a dormant period of around 35 Myr. The outermost regions of radio emission have a steep spectral index (α< − 1), indicative of old plasma. We connect the spectral index properties of the resolved source structure with the integrated fluxdensity spectral index of 4C 35.06 and suggest an explanation for its unusual integrated flux density spectral shape (a moderately steep power law with no discernible spectral break), possibly providing a proxy for future studies of more distant radio sources through inferring their detailed spectral index properties and activity history from their integrated spectral indices. The AGN is hosted by one of the galaxies located in the cluster core of Abell 407. We propose that it is intermittently active as it moves in the dense environment in the cluster core. In this scenario, the AGN turned on sometime in the past, and has produced the helical pattern of emission, possibly a sign of jet precession/merger during that episode of activity. Using LOFAR, we can trace the relic plasma from that episode of activity out to greater distances from the core than ever before. Using the the WSRT, we detect H I in absorption against the center of the radio source. The absorption profile is relatively broad (FWHM of 288 kms-1), similar to what is found in other clusters. The derived column density is NHI ~ 4 × 1020 cm-2 for a Tspin = 100 K. This detection supports the connection – already suggested for other restarted radio sources – between the presence of cold gas and restarting activity. The cold gas appears to be dominated by a blue-shifted component although the broad H I profile could also include gas with different kinematics. Understanding the duty cycle of the radio emission as well as the triggering mechanism for starting (or restarting) the radio-loud activity can provide important constraints to quantify the impact of AGN feedback on galaxy evolution. The study of these mechanisms at low frequencies using morphological and spectral information promises to bring new important insights in this field.
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  • Klassen, Anne F., et al. (författare)
  • Psychometric findings and normative values for the CLEFT-Q based on 2434 children and young adult patients with cleft lip and/or palate from 12 countries
  • 2018
  • Ingår i: CMAJ. - : CMA Joule Inc.. - 0820-3946. ; 190:15, s. 455-462
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: Patients with cleft lip and/or palate can undergo numerous procedures to improve appearance, speech, dentition and hearing. We developed a cleft-specific patientreported outcome instrument to facilitate rigorous international measurement and benchmarking. METHODS: Data were collected from patients aged 8-29 years with cleft lip and/or palate at 30 hospitals in 12 countries between October 2014 and November 2016. Rasch measurement theory analysis was used to refine the scales and to examine reliability and validity. Normative CLEFT-Q values were computed for age, sex and cleft type. RESULTS: Analysis led to the refinement of an eating and drinking checklist and 12 scales measuring appearance (of the face, nose, nostrils, teeth, lips, jaws and cleft lip scar), health-related quality of life (psychological, social, school, speech distress) and speech function. All scales met the requirements of the Rasch model. Analysis to explore differential item functioning by age, sex and country provided evidence to support the use of a common scoring algorithm for each scale for international use. Lower (worse) scores on CLEFT-Q scales were associated with having a speech problem, being unhappy with facial appearance, and needing future cleft-related treatments, providing evidence of construct validity. Normative values for age, sex and cleft type showed poorer outcomes associated with older age, female sex and having a visible cleft. INTERPRETATION: The CLEFT-Q represents a rigorously developed instrument that can be used internationally to collect and compare evidence-based outcomes data from patients aged 8-29 years of age with cleft lip and/or palate.
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  • Mikkelsen, Tarjei S, et al. (författare)
  • Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences
  • 2007
  • Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 447:7141, s. 167-177
  • Tidskriftsartikel (refereegranskat)abstract
    • We report a high-quality draft of the genome sequence of the grey, short-tailed opossum (Monodelphis domestica). As the first metatherian ('marsupial') species to be sequenced, the opossum provides a unique perspective on the organization and evolution of mammalian genomes. Distinctive features of the opossum chromosomes provide support for recent theories about genome evolution and function, including a strong influence of biased gene conversion on nucleotide sequence composition, and a relationship between chromosomal characteristics and X chromosome inactivation. Comparison of opossum and eutherian genomes also reveals a sharp difference in evolutionary innovation between protein-coding and non-coding functional elements. True innovation in protein-coding genes seems to be relatively rare, with lineage-specific differences being largely due to diversification and rapid turnover in gene families involved in environmental interactions. In contrast, about 20% of eutherian conserved non-coding elements (CNEs) are recent inventions that postdate the divergence of Eutheria and Metatheria. A substantial proportion of these eutherian-specific CNEs arose from sequence inserted by transposable elements, pointing to transposons as a major creative force in the evolution of mammalian gene regulation.
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6.
  • Shimwell, T. W., et al. (författare)
  • The LOFAR Two-metre Sky Survey: I. Survey description and preliminary data release
  • 2017
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 598, s. Art no A104-
  • Tidskriftsartikel (refereegranskat)abstract
    • The LOFAR Two-metre Sky Survey (LoTSS) is a deep 120-168 MHz imaging survey that will eventually cover the entire northern sky. Each of the 3170 pointings will be observed for 8 h, which, at most declinations, is sufficient to produce ~5? resolution images with a sensitivity of ~100 ?Jy/beam and accomplish the main scientific aims of the survey, which are to explore the formation and evolution of massive black holes, galaxies, clusters of galaxies and large-scale structure. Owing to the compact core and long baselines of LOFAR, the images provide excellent sensitivity to both highly extended and compact emission. For legacy value, the data are archived at high spectral and time resolution to facilitate subarcsecond imaging and spectral line studies. In this paper we provide an overview of the LoTSS. We outline the survey strategy, the observational status, the current calibration techniques, a preliminary data release, and the anticipated scientific impact. The preliminary images that we have released were created using a fully automated but direction-independent calibration strategy and are significantly more sensitive than those produced by any existing large-Area low-frequency survey. In excess of 44 000 sources are detected in the images that have a resolution of 25?, typical noise levels of less than 0.5 mJy/beam, and cover an area of over 350 square degrees in the region of the HETDEX Spring Field (right ascension 10h45m00s to 15h30m00s and declination 45°00?00? to 57°00?00?).
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  • Shimwell, T. W., et al. (författare)
  • The LOFAR Two-metre Sky Survey: II. First data release
  • 2019
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 622
  • Forskningsöversikt (refereegranskat)abstract
    • The LOFAR Two-metre Sky Survey (LoTSS) is an ongoing sensitive, high-resolution 120-168 MHz survey of the entire northern sky for which observations are now 20% complete. We present our first full-quality public data release. For this data release 424 square degrees, or 2% of the eventual coverage, in the region of the HETDEX Spring Field (right ascension 10h45m00s to 15h30m00s and declination 45°00′00″ to 57°00′00″) were mapped using a fully automated direction-dependent calibration and imaging pipeline that we developed. A total of 325 694 sources are detected with a signal of at least five times the noise, and the source density is a factor of ∼10 higher than the most sensitive existing very wide-area radio-continuum surveys. The median sensitivity is S144 MHz = 71 μJy beam -1 and the point-source completeness is 90% at an integrated flux density of 0.45 mJy. The resolution of the images is 6″ and the positional accuracy is within 0.2″. This data release consists of a catalogue containing location, flux, and shape estimates together with 58 mosaic images that cover the catalogued area. In this paper we provide an overview of the data release with a focus on the processing of the LOFAR data and the characteristics of the resulting images. In two accompanying papers we provide the radio source associations and deblending and, where possible, the optical identifications of the radio sources together with the photometric redshifts and properties of the host galaxies. These data release papers are published together with a further ∼20 articles that highlight the scientific potential of LoTSS.
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8.
  • Williams, W. L., et al. (författare)
  • LOFAR 150-MHz observations of the Bootes field: catalogue and source counts
  • 2016
  • Ingår i: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 460:3, s. 2385-2412
  • Tidskriftsartikel (refereegranskat)abstract
    • We present the first wide area (19 deg(2)), deep (a parts per thousand 120-150 mu Jy beam(-1)), high-resolution (5.6 x 7.4 arcsec) LOFAR High Band Antenna image of the Bootes field made at 130-169 MHz. This image is at least an order of magnitude deeper and 3-5 times higher in angular resolution than previously achieved for this field at low frequencies. The observations and data reduction, which includes full direction-dependent calibration, are described here. We present a radio source catalogue containing 6 276 sources detected over an area of 19 deg(2), with a peak flux density threshold of 5 sigma. As the first thorough test of the facet calibration strategy, introduced by van Weeren et al., we investigate the flux and positional accuracy of the catalogue. We present differential source counts that reach an order of magnitude deeper in flux density than previously achieved at these low frequencies, and show flattening at 150-MHz flux densities below 10 mJy associated with the rise of the low flux density star-forming galaxies and radio-quiet AGN.
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10.
  • Hardcastle, M. J., et al. (författare)
  • LOFAR/H-ATLAS: a deep low-frequency survey of the Herschel-ATLAS North Galactic Pole field
  • 2016
  • Ingår i: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 462:2, s. 1910-1936
  • Tidskriftsartikel (refereegranskat)abstract
    • We present Low-Frequency Array (LOFAR) High-Band Array observations of the Herschel-ATLAS North Galactic Pole survey area. The survey we have carried out, consisting of four pointings covering around 142 deg(2) of sky in the frequency range 126-173 MHz, does not provide uniform noise coverage but otherwise is representative of the quality of data to be expected in the planned LOFAR wide-area surveys, and has been reduced using recently developed 'facet calibration' methods at a resolution approaching the full resolution of the data sets (similar to 10 x 6 arcsec) and an rms off-source noise that ranges from 100 mu Jy beam(-1) in the centre of the best fields to around 2 mJy beam(-1) at the furthest extent of our imaging. We describe the imaging, cataloguing and source identification processes, and present some initial science results based on a 5 sigma source catalogue. These include (i) an initial look at the radio/far-infrared correlation at 150 MHz, showing that many Herschel sources are not yet detected by LOFAR; (ii) number counts at 150 MHz, including, for the first time, observational constraints on the numbers of star-forming galaxies; (iii) the 150-MHz luminosity functions for active and star-forming galaxies, which agree well with determinations at higher frequencies at low redshift, and show strong redshift evolution of the star-forming population; and (iv) some discussion of the implications of our observations for studies of radio galaxy life cycles.
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11.
  • O' Mahony, L, et al. (författare)
  • Impact of Long COVID on health and quality of life
  • 2022
  • Ingår i: HRB open research. - : F1000 Research Ltd. - 2515-4826. ; 5, s. 31-
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: The aim of this study was to measure the impact of post-acute sequelae of COVID-19 (PASC) on quality of life, mental health, ability to work and return to baseline health in an Irish cohort. Methods: We invited individuals with symptoms of COVID-19 lasting more than 14 days to participate in an anonymous online questionnaire. Basic demographic data and self-reported symptoms were recorded. Internationally validated instruments including the patient health questionnaire somatic, anxiety and depressive symptom scales (PHQ-SADS), the Patient Health Questionnaire-15 (PHQ-15) and Chadler fatigue scale (CFQ) were used. Results: We analysed responses from 988 participants with self-reported confirmed (diagnostic/antibody positive; 81%) or suspected (diagnostic/antibody negative or untested; 9%) COVID-19. The majority of respondents were female (88%), white (98%), with a median age of 43.0 (range 15 – 88 years old) and a median BMI of 26.0 (range 16 – 60). At the time of completing this survey, 89% of respondents reported that they have not returned to their pre-COVID-19 level of health. The median number of symptoms reported was 8 (range 0 to 33 symptoms), with a median duration of 12 months (range 1 to 20 months) since time of acute infection. A high proportion of PASC patients reported that they have a moderate or severe limitation in their ability to carry out their usual activities, 38% report their ability to work is severely limited and 33% report a moderate, or higher, level of anxiety or depression. Conclusion: The results of this survey of an Irish cohort with PASC are in line with reports from other settings, and we confirm that patients with PASC reported prolonged, multi-system symptoms which can significantly impact quality of life, affect ability to work and cause significant disability. Dedicated multidisciplinary, cross specialty supports are required to improve outcomes of this patient group.
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  • Asayama, Shinichiro, et al. (författare)
  • Three institutional pathways to envision the future of the IPCC
  • 2023
  • Ingår i: Nature Climate Change. - : Nature Portfolio. - 1758-678X .- 1758-6798. ; 13:9, s. 877-880
  • Tidskriftsartikel (refereegranskat)abstract
    • The IPCC has been successful at building its scientific authority, but it will require institutional reform for staying relevant to new and changing political contexts. Exploring a range of alternative future pathways for the IPCC can help guide crucial decisions about redefining its purpose.
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  • Shulevski, A., et al. (författare)
  • AGN duty cycle estimates for the ultra-steep spectrum radio relic VLSS J1431.8+1331
  • 2015
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 583, s. A89-
  • Tidskriftsartikel (refereegranskat)abstract
    • Context. Steep spectrum radio sources associated with active galactic nuclei (AGN) may contain remnants of past AGN activity episodes. Studying these sources gives us insight into the AGN activity history. Novel instruments like the LOw Frequency ARray (LOFAR) are enabling studies of these fascinating structures to be made at tens to hundreds of MHz with sufficient resolution to analyse their complex morphology. Aims. Our goal is to characterize the integrated and resolved spectral properties of VESS J1431+1331 and estimate source ages based on synchrotron radio emission models, thus putting constraints on the AGN duty cycle. Methods. Using a broad spectral coverage, we have derived spectral and curvature maps, and used synchrotron ageing models to determine the time elapsed from the last time the source plasma was energized. We used LOFAR, Giant Metrewave Radio Telescope (GMRT) and Jansky Very Large Array (VLA) data. Results. We confirm the morphology and the spectral index values found in previous studies of this object. Based on our ageing analysis, we infer that the AGN that created this source currently has very low levels of activity or that it is switched off. The derived ages for the larger source component range from around 60 to 130 Myr, hinting that the AGN activity decreased or stopped around 60 Myr ago. We observe that the area around the faint radio core located in the larger source component is the youngest, while the overall age of the smaller source component shows it to be the oldest part of the source. Conclusions. Our analysis suggests that VLSS J1431.8+1331 is an intriguing, two-component source. The larger component seems to host a faint radio core, suggesting that the source may be an AGN radio relic. The spectral index we observe from the smaller component is distinctly flatter at lower frequencies than the spectral index of the larger component, suggesting the possibility that the smaller component may be a shocked plasma bubble. From. the integrated source spectrum, we deduce that its shape and slope can be used as tracers of the activity history of this type of steep spectrum radio source. We discuss the implications this conclusion has for future studies of radio sources having similar characteristics.
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16.
  • Young, T., et al. (författare)
  • Durability of hybrid laminar flow control (HLFC) surfaces
  • 2003
  • Ingår i: Aerospace Science and Technology. - 1270-9638 .- 1626-3219. ; 7:3, s. 181-190
  • Tidskriftsartikel (refereegranskat)abstract
    • As a part of the European Commission sponsored HYLTEC (Hybrid Laminar Flow Technology) project, a SAAB 2000 aircraft - fitted with a number of small laser drilled panels on the wing leading edge - completed 20 months of routine service, the objective being to investigate contamination and durability aspects of Hybrid Laminar Flow Control (HLFC) suction surfaces. A post-flight test investigation of these panels, manufactured from Nd-YAG laser drilled titanium, aluminium and carbon fibre polyetheretherketone (PEEK) composite, has been conducted. Using Scanning Electron Microscopy (SEM), evidence of corrosion and damage was investigated. An optical inspection technique was used to measure hole geometries and the results were compared to pressure loss measurements through the panels. Titanium was found to be the most robust material, displaying no adverse affect from this exposure, whilst aluminium was found to be substantially less durable. The PEEK carbon fibre composite showed signs of surface degradation after only two months of flight trials. © 2003 Éditions scientifiques et médicales Elsevier SAS. All rights reserved.
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