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- Bailey, D. L., et al.
(author)
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Combined PET/MRI : Global Warming-Summary Report of the 6th International Workshop on PET/MRI, March 27-29, 2017, Tubingen, Germany
- 2018
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In: Molecular Imaging and Biology. - : SPRINGER. - 1536-1632 .- 1860-2002. ; 20:1, s. 4-20
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Research review (peer-reviewed)abstract
- The 6th annual meeting to address key issues in positron emission tomography (PET)/magnetic resonance imaging (MRI) was held again in Tubingen, Germany, from March 27 to 29, 2017. Over three days of invited plenary lectures, round table discussions and dialogue board deliberations, participants critically assessed the current state of PET/MRI, both clinically and as a research tool, and attempted to chart future directions. The meeting addressed the use of PET/MRI and workflows in oncology, neurosciences, infection, inflammation and chronic pain syndromes, as well as deeper discussions about how best to characterise the tumour microenvironment, optimise the complementary information available from PET and MRI, and how advanced data mining and bioinformatics, as well as information from liquid biomarkers (circulating tumour cells and nucleic acids) and pathology, can be integrated to give a more complete characterisation of disease phenotype. Some issues that have dominated previous meetings, such as the accuracy of MR-based attenuation correction (AC) of the PET scan, were finally put to rest as having been adequately addressed for the majority of clinical situations. Likewise, the ability to standardise PET systems for use in multicentre trials was confirmed, thus removing a perceived barrier to larger clinical imaging trials. The meeting openly questioned whether PET/MRI should, in all cases, be used as a whole-body imaging modality or whether in many circumstances it would best be employed to give an in-depth study of previously identified disease in a single organ or region. The meeting concluded that there is still much work to be done in the integration of data from different fields and in developing a common language for all stakeholders involved. In addition, the participants advocated joint training and education for individuals who engage in routine PET/MRI. It was agreed that PET/MRI can enhance our understanding of normal and disrupted biology, and we are in a position to describe the in vivo nature of disease processes, metabolism, evolution of cancer and the monitoring of response to pharmacological interventions and therapies. As such, PET/MRI is a key to advancing medicine and patient care.
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- Hadid, L. Z., et al.
(author)
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BepiColombo's Cruise Phase : Unique Opportunity for Synergistic Observations
- 2021
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In: Frontiers in Astronomy and Space Sciences. - : Frontiers Media S.A.. - 2296-987X. ; 8
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Journal article (peer-reviewed)abstract
- The investigation of multi-spacecraft coordinated observations during the cruise phase of BepiColombo (ESA/JAXA) are reported, with a particular emphasis on the recently launched missions, Solar Orbiter (ESA/NASA) and Parker Solar Probe (NASA). Despite some payload constraints, many instruments onboard BepiColombo are operating during its cruise phase simultaneously covering a wide range of heliocentric distances (0.28 AU-0.5 AU). Hence, the various spacecraft configurations and the combined in-situ and remote sensing measurements from the different spacecraft, offer unique opportunities for BepiColombo to be part of these unprecedented multipoint synergistic observations and for potential scientific studies in the inner heliosphere, even before its orbit insertion around Mercury in December 2025. The main goal of this report is to present the coordinated observation opportunities during the cruise phase of BepiColombo (excluding the planetary flybys). We summarize the identified science topics, the operational instruments, the method we have used to identify the windows of opportunity and discuss the planning of joint observations in the future.
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- Milillo, A., et al.
(author)
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Investigating Mercury's Environment with the Two-Spacecraft BepiColombo Mission
- 2020
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In: Space Science Reviews. - : Springer Science and Business Media LLC. - 0038-6308 .- 1572-9672. ; 216:5
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Research review (peer-reviewed)abstract
- The ESA-JAXA BepiColombo mission will provide simultaneous measurements from two spacecraft, offering an unprecedented opportunity to investigate magnetospheric and exospheric dynamics at Mercury as well as their interactions with the solar wind, radiation, and interplanetary dust. Many scientific instruments onboard the two spacecraft will be completely, or partially devoted to study the near-space environment of Mercury as well as the complex processes that govern it. Many issues remain unsolved even after the MESSENGER mission that ended in 2015. The specific orbits of the two spacecraft, MPO and Mio, and the comprehensive scientific payload allow a wider range of scientific questions to be addressed than those that could be achieved by the individual instruments acting alone, or by previous missions. These joint observations are of key importance because many phenomena in Mercury's environment are highly temporally and spatially variable. Examples of possible coordinated observations are described in this article, analysing the required geometrical conditions, pointing, resolutions and operation timing of different BepiColombo instruments sensors.
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- Witasse, O., et al.
(author)
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Interplanetary coronal mass ejection observed at STEREO-A, Mars, comet 67P/Churyumov-Gerasimenko, Saturn, and New Horizons en route to Pluto : Comparison of its Forbush decreases at 1.4, 3.1, and 9.9 AU
- 2017
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In: Journal of Geophysical Research - Space Physics. - 2169-9380 .- 2169-9402. ; 122:8, s. 7865-7890
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Journal article (peer-reviewed)abstract
- We discuss observations of the journey throughout the Solar System of a large interplanetary coronal mass ejection (ICME) that was ejected at the Sun on 14 October 2014. The ICME hit Mars on 17 October, as observed by the Mars Express, Mars Atmosphere and Volatile EvolutioN Mission (MAVEN), Mars Odyssey, and Mars Science Laboratory (MSL) missions, 44h before the encounter of the planet with the Siding-Spring comet, for which the space weather context is provided. It reached comet 67P/Churyumov-Gerasimenko, which was perfectly aligned with the Sun and Mars at 3.1 AU, as observed by Rosetta on 22 October. The ICME was also detected by STEREO-A on 16 October at 1 AU, and by Cassini in the solar wind around Saturn on the 12 November at 9.9AU. Fortuitously, the New Horizons spacecraft was also aligned with the direction of the ICME at 31.6 AU. We investigate whether this ICME has a nonambiguous signature at New Horizons. A potential detection of this ICME by Voyager 2 at 110-111 AU is also discussed. The multispacecraft observations allow the derivation of certain properties of the ICME, such as its large angular extension of at least 116 degrees, its speed as a function of distance, and its magnetic field structure at four locations from 1 to 10 AU. Observations of the speed data allow two different solar wind propagation models to be validated. Finally, we compare the Forbush decreases (transient decreases followed by gradual recoveries in the galactic cosmic ray intensity) due to the passage of this ICME at Mars, comet 67P, and Saturn.
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- Giono, Gabriel, et al.
(author)
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Origin of the Solar Rotation Harmonics Seen in the EUV and UV Irradiance
- 2021
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In: Solar Physics. - : Springer Nature. - 0038-0938 .- 1573-093X. ; 296:11
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Journal article (peer-reviewed)abstract
- Long-term periodicities in the solar irradiance are often observed with periods proportional to the solar rotational period of 27 days. These periods are linked either to some internal mechanism in the Sun or said to be higher harmonics of the rotation without further discussion of their origin. In this article, the origin of the peaks in periodicities seen in the solar extreme ultraviolet (EUV) and ultraviolet (UV) irradiance around the 7, 9, and 14 days periods is discussed. Maps of the active regions and coronal holes are produced from six images per day using the Spatial Possibilistic Clustering Algorithm (SPoCA), a segmentation algorithm. Spectral irradiance at coronal, transition-region/chromospheric, and photospheric levels are extracted for each feature as well as for the full disk by applying the maps to full-disk images (at 19.3, 30.4, and 170 nm sampling in the corona/hot flare plasma, the chromosphere/transition region, and the photosphere, respectively) from the Atmospheric Imaging Assembly (AIA) on board the Solar Dynamics Observatory (SDO) from January 2011 to December 2018. The peaks in periodicities at 7, 9, and 14 days as well as the solar rotation around 27 days can be seen in almost all of the solar irradiance time series. The segmentation also provided time series of the active regions and coronal holes visible area (i.e. in the area observed in the AIA images, not corrected for the line-of-sight effect with respect to the solar surface), which also show similar peaks in periodicities, indicating that the periodicities are due to the change in area of the features on the solar disk rather than to their absolute irradiance. A simple model was created to reproduce the power spectral density of the area covered by active regions also showing the same peaks in periodicities. Segmentation of solar images allows us to determine that the peaks in periodicities seen in solar EUV/UV irradiance from a few days to a month are due to the change in area of the solar features, in particular, active regions, as they are the main contributors to the total full-disk irradiance variability. The higher harmonics of the solar rotation are caused by the clipping of the area signal as the regions rotate behind the solar limb.
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- Wyatt, Jeremy L., et al.
(author)
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Self-Understanding and Self-Extension : A Systems and Representational Approach
- 2010
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In: IEEE T AUTON MENT DE. - 1943-0604. ; 2:4, s. 282-303
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Journal article (peer-reviewed)abstract
- There are many different approaches to building a system that can engage in autonomous mental development. In this paper, we present an approach based on what we term self-understanding, by which we mean the explicit representation of and reasoning about what a system does and does not know, and how that knowledge changes under action. We present an architecture and a set of representations used in two robot systems that exhibit a limited degree of autonomous mental development, which we term self-extension. The contributions include: representations of gaps and uncertainty for specific kinds of knowledge, and a goal management and planning system for setting and achieving learning goals.
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- Zender, J. J., et al.
(author)
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Segmentation of photospheric magnetic elements corresponding to coronal features to understand the EUV and UV irradiance variability
- 2017
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In: Astronomy and Astrophysics. - : EDP SCIENCES S A. - 0004-6361 .- 1432-0746. ; 605
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Journal article (peer-reviewed)abstract
- Context. The magnetic field plays a dominant role in the solar irradiance variability. Determining the contribution of various magnetic features to this variability is important in the context of heliospheric studies and Sun-Earth connection. Aims. We studied the solar irradiance variability and its association with the underlying magnetic field for a period of five years (January 2011-January 2016). We used observations from the Large Yield Radiometer (LYRA), the Sun Watcher with Active Pixel System detector and Image Processing (SWAP) on board PROBA2, the Atmospheric Imaging Assembly (AIA), and the Helioseismic and Magnetic Imager (HMI) on board the Solar Dynamics Observatory (SDO). Methods. The Spatial Possibilistic Clustering Algorithm (SPoCA) is applied to the extreme ultraviolet (EUV) observations obtained from the AIA to segregate coronal features by creating segmentation maps of active regions (ARs), coronal holes (CHs) and the quiet sun (QS). Further, these maps are applied to the full-disk SWAP intensity images and the full-disk (FD) HMI line-of-sight (LOS) magnetograms to isolate the SWAP coronal features and photospheric magnetic counterparts, respectively. We then computed fulldisk and feature-wise averages of EUV intensity and line of sight (LOS) magnetic flux density over ARs/CHs/QS/FD. The variability in these quantities is compared with that of LYRA irradiance values. Results. Variations in the quantities resulting from the segmentation, namely the integrated intensity and the total magnetic flux density of ARs/CHs/QS/FD regions, are compared with the LYRA irradiance variations. We find that the EUV intensity over ARs/CHs/QS/FD is well correlated with the underlying magnetic field. In addition, variations in the full-disk integrated intensity and magnetic flux density values are correlated with the LYRA irradiance variations. Conclusions. Using the segmented coronal features observed in the EUV wavelengths as proxies to isolate the underlying magnetic structures is demonstrated in this study. Sophisticated feature identification and segmentation tools are important in providing more insights into the role of various magnetic features in both the short-and long-term changes in the solar irradiance.
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