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- Elidottir, Anita S., et al.
(författare)
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Seaweed extract improves carbohydrate metabolism in overweight and obese adults
- 2021
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Ingår i: Current Nutrition and Food Science. - : Bentham Science Publishers B.V.. - 1573-4013. ; 17:2, s. 216-224
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Tidskriftsartikel (refereegranskat)abstract
- Background: Obesity is characterized by chronic low-grade inflammation and associated with type 2 diabetes. Seaweed is one of the largest producers of biomass in the marine environment and is a rich arsenal of functional ingredients that may possess the potential to prevent type 2 diabe-tes. Objective: The aim was to investigate the effects of seaweed extract on glucose metabolism and markers of inflammation in overweight and obese individuals. Methods: Participants (N=76, ≥40 years, body mass index ≥25 kg/m2) who volunteered for this 10-week randomized, controlled, doubly blinded intervention study, were randomized into an intervention group (seaweed extract, 3 capsules=1200 mg/day) or a control group (placebo, 3 capsules/day). The extract derived from the brown seaweed bladder wrack (Fucus vesiculosus). At baseline and endpoint of the study, fasting samples were analysed for blood glucose, insulin, inflammation mark-ers, liver enzymes and creatinine (renal function). Results: Drop out was 11.8% and not significantly different between groups. Fasting blood glucose and insulin were improved at the endpoint in the intervention group, but no changes were observed in the control group (corrected endpoint differences between groups: glucose=0.61 mmol/L, P=0.038; insulin=0.72 µU/L, P=0.038). Measures of inflammation, liver enzymes and renal function did not change significantly during the study. Conclusion: Ingestion of seaweed extract over 10 weeks improves glucose metabolism without af-fecting measures of inflammation, liver function or renal function.
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| 2. |
- Högberg, G, et al.
(författare)
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Does vitamin D play a role in depression? A review of clinical, epidemiological and biological studies
- 2014
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Ingår i: Current Nutrition and Food Science. - : Bentham Science Publishers B.V.. - 1573-4013 .- 2212-3881. ; 10:1, s. 16-28
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Tidskriftsartikel (refereegranskat)abstract
- There is a growing interest in the possible associations between vitamin D and depression. In this mini-review we present diagnostic criteria of different depression scales, with special focus on somatic complaints, possible links between depression and vitamin D and an overview of studies on vitamin D levels/vitamin D supplementation in depressed patients. We observed that complaints of a somatic character, potentially linked to vitamin D deficiency, are important parts of the diagnostic assessment in depression. Depressed patients often had low levels of vitamin D, and seven out of nine large (n>1000) observational studies showed an association between vitamin D levels and depression. Five studies of vitamin D supplementation in depressed patients with vitamin D deficiency showed significant reductions in depressive symptoms post-supplementation. However, only two of these studies were randomized controlled trials, and one of them had only 15 subjects. We recommend that depressed patients should generally be screened for vitamin D deficiency. Aside an increased risk of impaired bone health, individual patients may have symptoms of depression related to potentially deficient vitamin D levels. However, further randomized controlled studies of the effects of vitamin D supplementation in depressed patients are needed. © 2014 Bentham Science Publishers.
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