| 1. |
- Adalbjörnsson, Stefan, et al.
(författare)
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Conjugate priors for Gaussian emission plsa recommender systems
- 2016
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Ingår i: 2016 24th European Signal Processing Conference, EUSIPCO 2016. - 9780992862657 ; 2016-November, s. 2096-2100
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Konferensbidrag (refereegranskat)abstract
- Collaborative filtering for recommender systems seeks to learn and predict user preferences for a collection of items by identifying similarities between users on the basis of their past interest or interaction with the items in question. In this work, we present a conjugate prior regularized extension of Hofmann's Gaussian emission probabilistic latent semantic analysis model, able to overcome the over-fitting problem restricting the performance of the earlier formulation. Furthermore, in experiments using the EachMovie and MovieLens data sets, it is shown that the proposed regularized model achieves significantly improved prediction accuracy of user preferences as compared to the latent semantic analysis model without priors.
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| 3. |
- Andersen, Sören M., et al.
(författare)
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A scalable route to 5-substituted 3-isoxazolol fibrinolysis inhibitor AZD6564
- 2014
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Ingår i: Organic Process Research & Development. - : American Chemical Society (ACS). - 1083-6160 .- 1520-586X. ; 18:8, s. 952-959
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Tidskriftsartikel (refereegranskat)abstract
- A practical and chromatography-free multikilogram synthesis of a 3-isoxazolol containing antifibrinolytic agent, AZD6564, has been developed in eight steps and 7% overall yield starting from methyl 2-chloroisonicotinate. Highlights in the synthesis are a Negishi coupling and an enzymatic resolution of a racemic ester.
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| 11. |
- Andersson, Maria, et al.
(författare)
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Delay of appropriate antibiotic treatment is associated with high mortality in patients with community-onset sepsis in a Swedish setting
- 2019
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Ingår i: European Journal of Clinical Microbiology and Infectious Diseases. - : SPRINGER. - 0934-9723 .- 1435-4373. ; 38:7, s. 1223-1234
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Tidskriftsartikel (refereegranskat)abstract
- Early appropriate antimicrobial therapy is crucial in patients with sepsis and septic shock. Studies often focus on time to first dose of appropriate antibiotics, but subsequent dosing is equally important. Our aim was to investigate the impact of fulfillment of early treatment, with focus on appropriate administration of first and second doses of antibiotics, on 28-day mortality in patients with community-onset severe sepsis and septic shock. A retrospective study on adult patients admitted to the emergency department with community-onset sepsis and septic shock was conducted 2012-2013. The criterion early appropriate antibiotic treatment was defined as administration of the first dose of adequate antibiotics within 1h, and the second dose given with less than 25% delay after the recommended dose interval. A high-risk patient was defined as a septic patient with either shock within 24h after arrival or red triage level on admittance according to the Medical Emergency Triage and Treatment System Adult. Primary endpoint was 28-day mortality. Of 90 patients, less than one in four (20/87) received early appropriate antibiotic treatment, and only one in three (15/44) of the high-risk patients. The univariate analysis showed a more than threefold higher mortality among high-risk patients not receiving early appropriate antibiotic treatment. Multivariable analysis identified early non-appropriate antibiotic treatment as an independent predictor of mortality with an odds ratio for mortality of 10.4. Despite that the importance of early antibiotic treatment has been established for decades, adherence to this principle was very poor.
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| 12. |
- Austgen, M, et al.
(författare)
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Sputter yield amplification by tungsten doping of Al(2)O(3) employing reactive serial co-sputtering : process characteristics and resulting film properties
- 2011
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Ingår i: Journal of Physics D. - : IOP Publishing. - 0022-3727 .- 1361-6463. ; 44:34, s. 345501-
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Tidskriftsartikel (refereegranskat)abstract
- The deposition rate of reactively sputtered Al(2)O(3) coatings is demonstrated to increase by 80% upon tungsten doping of the used aluminium target. This effect is based on the recoil of the sputtering species at implanted dopants below the target surface and is termed sputter yield amplification. For the investigation of this effect, a novel type of magnetron sputter deposition system is employed that facilitates serial co-sputtering. In this technique doping of the elementary target is enabled by a dynamic sputtering process from an auxiliary cathode. In our case, the rotating aluminium target is dynamically coated with tungsten from this auxiliary cathode. Since the primary target rotates, the auxiliary cathode is placed in series with the primary erosion zone. The deposition rate of Al(2)O(3) can be considerably increased in this process already for very low concentrations of approximately 1% of tungsten in the resulting film. A characterization of the dynamics of reactive sputtering as a function of target rotation speed is performed.
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| 13. |
- Barankova, Hana, et al.
(författare)
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Abnormal High Rate Deposition of TiN Films by the Radio Frequency Plasma Jet System
- 1995
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Ingår i: J Electrochem Soc. - 0013-4651. ; 142:3, s. 883-887
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Tidskriftsartikel (refereegranskat)abstract
- Radio frequency Ar and Ar + N-2 plasma jets generated in a hollow electrode terminated by a small size Ti nozzle were used for deposition of Ti and TiN films. The regime with low content of reactive gas resulted in an extreme enhancement of TiN deposition
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| 14. |
- Barankova, Hana, et al.
(författare)
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Characterization of the linear arc discharge (LAD) source for film deposition
- 1997
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Ingår i: SURFACE & COATINGS TECHNOLOGY. - 0257-8972. ; 94-5:1-3, s. 578-582
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Tidskriftsartikel (refereegranskat)abstract
- The linear arc discharge (LAD) source is a parallel plate hollow cathode with a magnetic field perpendicular to the plates near the outlet slit of the cathode. The hollers cathode discharge is generated by radio frequency (rf) power and is confined mainly
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| 17. |
- Barankova, Hana, et al.
(författare)
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Hysteresis effects in the sputtering process using two reactive gases
- 1995
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Ingår i: Thin Solid Films. - 0040-6090. ; 260:2, s. 181-186
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Tidskriftsartikel (refereegranskat)abstract
- The reactive sputtering process involving two reactive gases has been investigated. Sputtering titanium in the presence of oxygen and nitrogen in argon was studied by means of optical emission and mass spectrometries. The experiments reveal the mechanism
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| 18. |
- Barankova, Hana, et al.
(författare)
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Linear arc discharge (LAD): A new type of hollow cathode plasma source
- 1996
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Ingår i: SURFACE & COATINGS TECHNOLOGY. - 0257-8972. ; 87-8:1-3, s. 377-380
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Tidskriftsartikel (refereegranskat)abstract
- A novel linearly scalable source for low pressure plasma processing is described. The source is based on a parallel plate hot hollow cathode in a focusing magnetic field which allows generation of a linearly uniform plasma in a gas admitted into the slit
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| 19. |
- Barankova, Hana, et al.
(författare)
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Metastable assisted deposition of TiN films
- 1995
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Ingår i: Appl Phys Lett. - 0003-6951. ; 67:11, s. 1521-1523
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Tidskriftsartikel (refereegranskat)abstract
- An excess heat from an exothermic reaction of metastable Ar (4(3)P(0)) and Ar (4(3)P(2)) atoms with N-2 molecules at low contents of N-2 in Ar was found to be responsible for an enhanced thermionic emission, an enhanced production of Ti target vapor, an i
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| 22. |
- Barankova, Hana, et al.
(författare)
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The radio frequency hollow cathode plasma jet arc for the film deposition
- 1996
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Ingår i: JOURNAL OF VACUUM SCIENCE & TECHNOLOGY A-VACUUM SURFACES AND FILMS. - 0734-2101. ; 14:6, s. 3033-3038
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Tidskriftsartikel (refereegranskat)abstract
- The radio frequency hollow cathode plasma jet (RPJ or RHCPJ) are discharge is studied for an activated reactive deposition of TiN films. The presence of low content of nitrogen in argon enables reaching the are regime at lower powers than in pure argon. T
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| 23. |
- Barankova, Hana, et al.
(författare)
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Titanium nitride deposited by high rate rf hollow cathode plasma jet reactive process
- 1995
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Ingår i: VACUUM. - 0042-207X. ; 46:12, s. 1433-1438
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Tidskriftsartikel (refereegranskat)abstract
- A radio frequency hollow cathode plasma jet (RPJ or RHCPJ) with a tubular Ti nozzle as a source of metal particles was used for the reactive deposition of TiN. The results of optical emission spectroscopy (OES), temperature measurements at the active zone
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| 24. |
- Bardos, Ladislav, et al.
(författare)
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A new method for film deposition in the discharge of target metal vapour
- 1995
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Ingår i: Surface and Coatings Technology. - 0257-8972. ; 72:3, s. 174-180
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Tidskriftsartikel (refereegranskat)abstract
- A new method for generation of a discharge in its own metal vapour of an r.f.-excited electrode is described. The method is based on the r.f. plasma jet (RPJ) system utilizing a small size r.f. nozzle in which a hollow cathode-type discharge is generated.
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| 27. |
- Bardos, Ladislav, et al.
(författare)
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Diamond deposition in a microwave electrode discharge at reduced pressures
- 1997
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Ingår i: DIAMOND AND RELATED MATERIALS. - 0925-9635. ; 6:2-4, s. 224-229
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Tidskriftsartikel (refereegranskat)abstract
- Diamond deposition on healed Si-substrates was studied under microwave discharge generated by an electrode-antenna either in a ''point-to-plane'' arrangement or in a ''parallel-plane'' arrangement at gas pressures of 1-15 Torr in a mixture of hydrogen wit
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| 35. |
- Bardos, Ladislav, et al.
(författare)
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PECVD by hollow cathodes
- 1998
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Ingår i: Proceedings of the 41st Annual Tech.Conf. of the Society of Vacuum Coaters (SVC), Boston 1998, ISSN 0737-5921, Paper P-1, Proc.. ; , s. 315-320
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Konferensbidrag (refereegranskat)
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| 40. |
- Bardos, Ladislav, et al.
(författare)
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Thin film processing by the radio frequency hollow cathodes
- 1997
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Ingår i: SURFACE & COATINGS TECHNOLOGY. - 0257-8972. ; 97:1-3, s. 723-728
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Tidskriftsartikel (refereegranskat)abstract
- The main features of the radio frequency (RF) hollow cathodes for thin film processing are summarized. The utilization of cylindrical RF hollow cathodes in both the plasma-enhanced chemical vapour deposition (PECVD) and the physical vapour deposition (PVD
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| 48. |
- Bengtsson, Caroline, 1975-
(författare)
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Nasal obstruction – impact on insomnia symptoms and sleep-disordered breathing
- 2019
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Background: Nasal obstruction is very common in the general population, but the role of nasal obstruction in sleep quality is not clear. Nasal obstruction is also prevalent in patients with obstructive sleep apnoea (OSA) and may contribute to poor adherence to continuous positive airway pressure (CPAP) treatment.Aims: To investigate the impact of subjective nasal obstruction, as a single symptom or as part of chronic rhinosinusitis (CRS), in both objective and subjective sleep quality, in three different population based cohorts. Another aim was to investigate the usefulness of the Sinonasal Outcome Test-22 (SNOT-22) and peak nasal inspiratory flow (PNIF) in the treatment of OSA patients.Methods and results: In paper I (the SHE-study), a community-based sample of 400 women were investigated with polysomnography and questions on sleep quality, daytime- and nasal symptoms. Women with nasal obstruction at night (n=30) had significantly higher prevalence of several night time symptoms and excessive daytime sleepiness (EDS), but the polysomnography was normal.In paper II (the GA2LEN study, n= 26, 647) and paper III (RHINE II and RHINE III studies, n= 5, 145) questionnaires on sleep quality, daytime- and nasal symptoms were used, and CRS was defined according to the epidemiological diagnostic criteria of the European Position Paper of Rhinosinusitis and Nasal Polyps (EPOS). In paper II, sleep problems were highly prevalent in CRS, and there was a dose-response relationship between the disease severity of CRS and sleep problems. The addition of persistent allergic rhinitis to CRS further increased the risk of sleep problems.In paper III, 2.7% of individuals without nasal symptoms at baseline had developed CRS at follow-up 10 years later. Strong associations between incident CRS and impaired sleep quality and EDS were found. Three insomnia symptoms at baseline increased the risk for CRS at follow-up.In paper IV, 197 OSA patients initiating CPAP treatment were investigated before starting CPAP and at the follow-up 3-4 weeks later. SNOT-22 scores were generally high among all OSA patients indicating a large sinonasal disease burden, and improved among those with CPAP adherence ≥ 4 hours/night. A low PNIF value increased the risk for poor CPAP adherence.Conclusions: Subjective nasal obstruction at night impairs subjective sleep quality in women, but does not affect objective sleep quality. CRS impairs subjective sleep quality, and insomnia symptoms may be a risk factor for CRS. SNOT-22 and PNIF may be useful tools in the treatment of OSA patients.
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