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- Ferrario, M., et al.
(author)
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IRIDE : Interdisciplinary research infrastructure based on dual electron linacs and lasers
- 2014
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In: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 740, s. 138-146
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Journal article (peer-reviewed)abstract
- This paper describes the scientific aims and potentials as well as the preliminary technical design of RUDE, an innovative tool for multi-disciplinary investigations in a wide field of scientific, technological and industrial applications. IRIDE will be a high intensity "particles factory", based on a combination of high duty cycle radio-frequency superconducting electron linacs and of high energy lasers. Conceived to provide unique research possibilities for particle physics, for condensed matter physics, chemistry and material science, for structural biology and industrial applications, IRIDE will open completely new research possibilities and advance our knowledge in many branches of science and technology. [RIDE is also supposed to be realized in subsequent stages of development depending on the assigned priorities.
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- Krendzel, A., et al.
(author)
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Framework for IMS service scenario implementation
- 2011
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In: Testbeds and Research Infrastructures. - Berlin, Heidelberg : Springer Berlin Heidelberg. - 9783642178504 - 9783642178511 ; , s. 684-702
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Conference paper (peer-reviewed)abstract
- This paper presents an experimental framework for implementation of an IMS/NGN reference service scenario by means of open source software. Multiple service enablers are deployed to build this service scenario. Interoperability tests between the deployed IMS entities and user equipment are carried out, as well as performance measurements of signaling overhead and delay of different IMS procedures involved to support the service scenario. Then, some preliminary results are obtained. After that, the IMS prototype is integrated with in-lab UMTS/HSDPA and WLAN networks to test IMS procedures in more close-to-real environment. Additionally, practical experiences with the IMS testbed deployment are discussed.
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- Schymanski, Emma L, et al.
(author)
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Non-target screening with high-resolution mass spectrometry : critical review using a collaborative trial on water analysis
- 2015
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In: Analytical and Bioanalytical Chemistry. - : Springer Berlin/Heidelberg. - 1618-2642 .- 1618-2650. ; 407:21, s. 6237-6255
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Research review (peer-reviewed)abstract
- In this article, a dataset from a collaborative non-target screening trial organised by the NORMAN Association is used to review the state-of-the-art and discuss future perspectives of non-target screening using high-resolution mass spectrometry in water analysis. A total of 18 institutes from 12 European countries analysed an extract of the same water sample collected from the River Danube with either one or both of liquid and gas chromatography coupled with mass spectrometry detection. This article focuses mainly on the use of high resolution screening techniques with target, suspect, and non-target workflows to identify substances in environmental samples. Specific examples are given to emphasise major challenges including isobaric and co-eluting substances, dependence on target and suspect lists, formula assignment, the use of retention information, and the confidence of identification. Approaches and methods applicable to unit resolution data are also discussed. Although most substances were identified using high resolution data with target and suspect-screening approaches, some participants proposed tentative non-target identifications. This comprehensive dataset revealed that non-target analytical techniques are already substantially harmonised between the participants, but the data processing remains time-consuming. Although the objective of a "fully-automated identification workflow" remains elusive in the short term, important steps in this direction have been taken, exemplified by the growing popularity of suspect screening approaches. Major recommendations to improve non-target screening include better integration and connection of desired features into software packages, the exchange of target and suspect lists, and the contribution of more spectra from standard substances into (openly accessible) databases.
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