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- Ek, Torben, 1963, et al.
(author)
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Proinflammatory cytokines mediate the systemic inflammatory response associated with high-dose cytarabine treatment in children.
- 2001
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In: Medical and pediatric oncology. - 0098-1532. ; 37:5, s. 459-64
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Journal article (peer-reviewed)abstract
- Treatment with high-dose cytarabine (1-beta-D-arabinofuranosylcytosine) is often associated with an acute febrile reaction sometimes including abdominal pain, myalgia, and rash. The similarity of these symptoms to those caused by hypersecretion of cytokines in the systemic inflammatory response syndrome (SIRS) prompted us to investigate the plasma levels of proinflammatory cytokines during treatment of children with high-dose cytarabine.
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