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- Magnusson, Susanne, et al.
(författare)
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Higher occurrence of childhood cancer in families with germline mutations in BRCA2, MMR and CDKN2A genes.
- 2008
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Ingår i: Familial Cancer. - : Springer Science and Business Media LLC. - 1389-9600 .- 1573-7292. ; 7, s. 331-337
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Tidskriftsartikel (refereegranskat)abstract
- The contribution of hereditary factors for development of childhood tumors is limited to some few known syndromes associated with predominance of tumors in childhood. Occurrence of childhood tumors in hereditary cancer syndromes such as BRCA1/2 associated breast and ovarian cancer, DNA-mismatch repair (MMR) genes associated hereditary non polyposis colorectal cancer and CDKN2A associated familial malignant melanoma are very little studied. Herein we report the prevalence of childhood tumors (diagnosed
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