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1.	Alajbeg, Ivan, et al. (author) Intraoralelectrostimulator for xerostomia relief : along-term, multicenter, open-label, uncontrolled, clinical trial 2012 In: Oral surgery, oral medicine, oral pathology and oral radiology. - : Elsevier. - 2212-4403 .- 2212-4411. ; 113:6, s. 773-781 Journal article (peer-reviewed)abstract OBJECTIVE: A previous sham-controlled multinational study demonstrated the short-term efficacy and safety for xerostomia treatment of an intraoral device that delivers electrostimulation to the lingual nerve. The objective of this study was to test the hypothesis that those beneficial effects would be sustained over an 11-month period. STUDY DESIGN: The device was tested on a mixed sample of 94 patients with xerostomia in an open-label, uncontrolled, prospective multicenter trial. Statutory outcome assessments were done at 5th, 8th, and 11th months and analyzed by multiple comparisons. RESULTS: Improvements achieved at month 5 from baseline were sustained throughout the follow-up period for the primary outcome, xerostomia severity, and the secondary outcomes resting whole salivary flow rate, xerostomia frequency, oral discomfort, and difficulties in speech, swallowing, and sleeping. No significant side effects were detected. CONCLUSIONS: The beneficial effects of a removable intraoral electrostimulating device were sustained for an 11-month period.
2.	Lim, Stephen S, et al. (author) A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. 2012 In: Lancet. - 1474-547X. ; 380:9859, s. 2224-60 Journal article (peer-reviewed)abstract Quantification of the disease burden caused by different risks informs prevention by providing an account of health loss different to that provided by a disease-by-disease analysis. No complete revision of global disease burden caused by risk factors has been done since a comparative risk assessment in 2000, and no previous analysis has assessed changes in burden attributable to risk factors over time.

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Type of publication: journal article (2)

Type of content: peer-reviewed (2)

Author/Editor: Romieu, Isabelle (1); Petzold, Max, 1973 (1); Brunekreef, Bert (1); Sapkota, Amir (1); Farzadfar, Farshad (1); Jonas, Jost B. (1); show more...; Khang, Young-Ho (1); Lopez, Alan D. (1); Lozano, Rafael (1); Malekzadeh, Reza (1); Micha, Renata (1); Mozaffarian, Dariush (1); Naghavi, Mohsen (1); Vos, Theo (1); Murray, Christopher ... (1); Lim, Stephen S. (1); Mensah, George A. (1); Salomon, Joshua A. (1); Gakidou, Emmanuela (1); Woolf, Anthony D (1); Giovannucci, Edward (1); Alajbeg, Ivan (1); Falcão, Denise P (1); Tran, Simon D (1); Martín-Granizo, Rafa ... (1); Lafaurie, Gloria I (1); Bautista Mendoza, Gl ... (1); Pejda, Slavica (1); Vuleti?, Lea (1); Mantilla, Rubén (1); Leal, Soraya C (1); Barreto Bezerra, Ana ... (1); Ménard, Henri A (1); Kimoto, Suguru (1); Pan, Shaoxia (1); Maniegas Lozano, Mar ... (1); Krushinski, Cheryl A (1); Melilli, Dario (1); Campisi, Giuseppina (1); Paderni, Carlo (1); Matranga, Domenica (1); Yepes, Juan F (1); Lindh, Liselott (1); Koray, Meltem (1); Mumcu, Gonca (1); Elad, Sharon (1); Zeevi, Itai (1); Aldape, Beatriz C (1); López Sánchez, Rodri ... (1); Lassauzay, Clarie L (1); show less...

University: University of Gothenburg (1); Malmö University (1)

Language: English (2)

Research subject (UKÄ/SCB): Medical and Health Sciences (2)

Year: 2012 (2)Undo refine

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