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- Galakhov, VR, et al.
(author)
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Co 3d-level position in ZnS : Co semiconductors
- 2003
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In: Physical Review B (Condensed Matter and Materials Physics). - 1098-0121. ; 68:3: 033204
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Journal article (peer-reviewed)abstract
- Experimental studies of x-ray photoelectron and Co Lalpha x-ray emission spectra of the ZnS:Co semiconductor were carried out. It was established that Co ions are present in isovalent Co2+ configuration and that the Co 3d impurity states are localized above the top of the valence band by 1.0 +/- 0.2 eV.
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- Rivera, C, et al.
(author)
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BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion
- 2002
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In: Journal of Cell Biology. - : Rockefeller University Press. - 0021-9525 .- 1540-8140. ; 159:5, s. 747-752
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Journal article (peer-reviewed)abstract
- Pathophysiological activity and various kinds of traumatic insults are known to have deleterious long-term effects on neuronal Cl- regulation, which can lead to a suppression of fast postsynaptic GABAergic responses. Brain-derived neurotrophic factor (BDNF) increases neuronal excitability through a conjunction of mechanisms that include regulation of the efficacy of GABAergic transmission. Here, we show that exposure of rat hippocampal slice cultures and acute slices to exogenous BDNF or neurotrophin-4 produces a TrkB-mediated fall in the neuron-specific K+-Cl- cotransporter KCC2 mRNA and protein, as well as a consequent impairment in neuronal Cl- extrusion capacity. After kindling-induced seizures in vivo, the expression of KCC2 is down-regulated in the mouse hippocampus with a spatio-temporal profile complementary to the up-regulation of TrkB and BDNF. The present data demonstrate a novel mechanism whereby BDNF/TrkB signaling suppresses chloride-dependent fast GABAergic inhibition, which most likely contributes to the well-known role of TrkB-activated signaling cascades in the induction and establishment of epileptic activity.
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- Stenman, Anders, et al.
(author)
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Model-on-Demand Identification for Control : An Experimental Study and Feasibility Analysis for MOD-Based Predictive Control
- 2000
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In: Proceedings of the 12th IFAC Symposium on System Identification. - Linköping : Linköping University Electronic Press. - 9780080435459 ; , s. 439-444
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Conference paper (peer-reviewed)abstract
- An experimental study of "Model-on-Demand" (MoD) identification is made on a pilot-scale brine-water mixing tank. MoD estimation is compared against semi-physical modeling techniques using identification data generated from a systematically designed m-level Pseudo Random Sequence (PRS) input. The estimated models are the basis for evaluating the usefulness of MoD-based Model Predictive Control (MPC). For this application, MoD-MPC is shown to provide better performance at high bandwidths compared to a linear MPC controller.
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