| 1. |
- Corrales, M. A., et al.
(författare)
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Methodology to geometrically age human body models to average and subject-specific anthropometrics, demonstrated using a small stature female model assessed in a side impact
- 2023
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Ingår i: Computer Methods in Biomechanics and Biomedical Engineering. - : Informa UK Limited. - 1476-8259 .- 1025-5842. ; 26:10, s. 1208-1219
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Tidskriftsartikel (refereegranskat)abstract
- The aged population has been associated with an increased risk of injury in car-crash, creating a critical need for improved assessment of safety systems. Finite element human body models (HBMs) have been proposed, but require representative geometry of the aged population and high mesh quality. A new hybrid Morphing-CAD methodology was applied to a 26-year-old (YO) 5th percentile female model to create average 75YO and subject-specific 86YO HBMs. The method achieved accurate morphing targets while retaining high mesh quality. The three HBMs were integrated into a side sled impact test demonstrating similar kinematic response but differing rib fracture patterns.
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| 2. |
- Larsson, Karl-Johan, 1985, et al.
(författare)
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Evaluation of a diverse population of morphed human body models for prediction of vehicle occupant crash kinematics
- 2022
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Ingår i: Computer Methods in Biomechanics and Biomedical Engineering. - : Informa UK Limited. - 1476-8259 .- 1025-5842. ; 25:10, s. 1125 -1155
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Tidskriftsartikel (refereegranskat)abstract
- Morphing can be used to alter human body models (HBMs) to represent a diverse population of occupants in car crashes. The mid-sized male SAFER HBM v9 was parametrically morphed to match 22 Post Mortem Human Subjects, loaded in different configurations. Kinetics and kinematics were compared for the morphed and baseline HBMs. In frontal impacts, the morphed HBMs correlated closer with the kinematics of obese subjects, but lower to small females. In lateral impacts HBM responses were too stiff. This study outlines a necessary evaluation of all HBMs that should be morphed to represent the diverse population in vehicle safety evaluations.
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| 3. |
- Moshksayan, K., et al.
(författare)
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In-silico investigation of airflow and micro-particle deposition in human nasal airway pre- and post-virtual transnasal sphenoidotomy surgery
- 2022
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Ingår i: Computer Methods in Biomechanics and Biomedical Engineering. - : Informa UK Limited. - 1025-5842 .- 1476-8259. ; 25:9, s. 1000-1014
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Tidskriftsartikel (refereegranskat)abstract
- Sphenoid sinus, located posterior to the nasal cavity, is difficult to reach for a surgery. Several operation procedures are available for sphenoidotomy, including endoscopic surgeries. Although the endoscopic sinus surgery is minimally invasive with low post-operative side effects, further optimization is required. Transnasal sphenoidotomy is a low invasive alternative to transethmoidal sphenoidotomy, but it still needs to be studied to understand its effects on the airflow pattern and the particle deposition. In this work, we simulated airflow and the micro-particle deposition in the nasal airway of a middle-aged man to investigate the change in particle deposition in the sphenoid sinus after virtual transnasal sphenoidotomy surgery. The results demonstrated that after transnasal sphenoidotomy, particle deposition in the targeted sphenoid sinus was an order of magnitude lower than that observed after virtual transethmoidal sphenoidotomy surgery. In addition, the diameter of the particles for the peak deposition fraction in the targeted sinus was shifted to smaller diameters after the transnasal sphenoidotomy surgery compared with that in the post-transethmoidal condition. These results suggest that the endoscopic transnasal sphenoidotomy can be a better procedure for sphenoid surgeries as it decreases the chance of bacterial contaminations and consequently lowers the surgical side effects and recovery time.
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| 4. |
- Paz, Alexander, et al.
(författare)
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A novel knee joint model in FEBio with inhomogeneous fibril-reinforced biphasic cartilage simulating tissue mechanical responses during gait : data from the osteoarthritis initiative
- 2023
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Ingår i: Computer Methods in Biomechanics and Biomedical Engineering. - : Informa UK Limited. - 1025-5842 .- 1476-8259. ; 26:11, s. 1353-1367
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Tidskriftsartikel (refereegranskat)abstract
- We developed a novel knee joint model in FEBio to simulate walking. Knee cartilage was modeled using a fibril-reinforced biphasic (FRB) formulation with depth-wise collagen architecture and split-lines to account for cartilage structure. Under axial compression, the knee model with FRB cartilage yielded contact pressures, similar to reported experimental data. Furthermore, gait analysis with FRB cartilage simulated spatial and temporal trends in cartilage fluid pressures, stresses, and strains, comparable to those of a fibril-reinforced poroviscoelastic (FRPVE) material in Abaqus. This knee joint model in FEBio could be used for further studies of knee disorders using physiologically relevant loading.
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| 5. |
- Simkheada, Tulashi, et al.
(författare)
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Comparison of constitutive models for meniscus and their effect on the knee joint biomechanics during gait
- 2023
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Ingår i: Computer Methods in Biomechanics and Biomedical Engineering. - : Informa UK Limited. - 1025-5842 .- 1476-8259. ; 26:16, s. 2008-2021
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Tidskriftsartikel (refereegranskat)abstract
- Mechanical behavior of meniscus can be modeled using constitutive material models of varying complexity, such as isotropic elastic or fibril reinforced poroelastic (FRPE). However, the FRPE material is complex to implement, computationally demanding in 3D geometries, and simulation is time-consuming. Hence, we aimed to quantify the most suitable and efficient constitutive model of meniscus for simulation of cartilage responses in the knee joint during walking. We showed that simpler constitutive material models can reproduce similar cartilage responses to a knee model with the FRPE meniscus, but only knee models that consider orthotropic elastic meniscus can also reproduce meniscus responses adequately.
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| 6. |
- Valdano, M., et al.
(författare)
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Evaluation of AIS3+ car occupant injuries using deterministic and probabilistic methods in frontal crashes
- 2023
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Ingår i: Computer Methods in Biomechanics and Biomedical Engineering. - 1476-8259 .- 1025-5842. ; In Press
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Tidskriftsartikel (refereegranskat)abstract
- Computational modelling was used to assess the capability of a deterministic and a probabilistic method to predict the incidence of AIS3+ injuries in passenger car occupants by comparing the predictions of the methods to the actual injuries observed in real-world crashes. The likelihood of sustaining an injury was first calculated using a computer model for a selected set of injury criteria in different impact conditions based on real-world crashes; AIS3+ injuries were then predicted using each method separately. Regardless of the method, the number of serious injuries was over-predicted. It was also noted that the used injury criteria suggested the occurrence of specific injuries that were not observed in the real world. Although both methods are susceptible to be adapted to improve their predictions, the question of the suitability of using some of the most commonly accepted injury criteria used with crash test dummies for injury assessment with human body models deserves further research.
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