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- Philipson, Joakim, 1958-
(författare)
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The Purpose of Evolution : the 'struggle for existence' in the Russian-Jewish press 1860-1900
- 2008
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- In late 19th century Russia, Darwinism was viewed as a measuring-rod of modernity. Thus, the Jewish reception of Darwinism may serve as an indicator of the extent to which the Jews in Russia were part of the modernization of Russian society. But the Darwinian concept of evolution of species through natural selection is considered incompatible with a teleological worldview, including a God-given plan for creation. This thesis addresses a twofold problem. One concerns the difficulties of reconciling Darwinism with Judaism and its traditional view of a God-given purpose in creation. The other problem is to explain the possible motives of the Jewish intellectuals for using Darwinian concepts such as the ‘struggle for existence’ in journal articles in the emerging Russian-Jewish press. The study employs discourse analysis, and the concept of isomorphism from institutional theory, for the examination of key concepts, citations, implied readers and purposes in a selection of journal articles from the Russian-Jewish press of the period 1860-1900. Contrasting with the lively general Russian debate on Darwinism, the results show that the Jews in Russia were rather reluctant to discuss Darwinism in the Russian-Jewish press. Censorship, other constraints and imminent problems facing the Jews, such as defence against growing anti-Semitism, are indicated as possible causes of the minimal evidence of a Jewish reception of Darwinism that was found. It was only to the extent that Darwinian concepts such as the ‘struggle for existence’ could be employed to address these more pressing issues that they were they found useful in a Jewish context. The results further imply that the integration between Russian and Jewish intellectuals during this period was weak, as reflected by the insignificant number of references to Russian sources in the selection of Jewish journal articles that were examined.
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| 2. |
- Tandstad, Torgrim, et al.
(författare)
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Risk-adapted treatment in clinical stage I nonseminomatous germ cell testicular cancer: the SWENOTECA management program.
- 2009
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Ingår i: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. - 1527-7755 .- 0732-183X. ; 27:13, s. 2122-8
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: To offer minimized risk-adapted adjuvant treatment on a nationwide basis for patients with clinical stage 1 (CS1) nonseminomatous germ-cell testicular cancer (NSGCT). The aim was to reduce the risk of relapse and thereby reducing the need of later salvage chemotherapy while maintaining a high cure rate. PATIENTS AND METHODS: From 1998 to 2005, 745 Norwegian and Swedish patients were included into a prospective, community-based multicenter Swedish and Norwegian Testicular Cancer Project (SWENOTECA) management program. Treatment strategy depended on the presence or absence of vascular tumor invasion (VASC). VASC-positive patients were recommended brief adjuvant chemotherapy (ACT) with bleomycin, etoposide, and cisplatin (BEP), whereas VASC-negative patients could choose between ACT and surveillance. RESULTS: At a median follow-up of 4.7 years, there have been 51 relapses. On surveillance, 41.7% of VASC+ patients relapsed, compared with 13.2% of VASC- patients. After one course of BEP, 3.2% of VASC+ and 1.3% of VASC- patients relapsed. The toxicity of adjuvant BEP was low. Eight patients have died, none died from progressive disease. CONCLUSION: One course of adjuvant BEP reduces the risk of relapse by approximately 90% in both VASC+ and VASC- CS1 NSGCT, and may be a new option as initial treatment for all CS1 NSGCT. One course of adjuvant BEP for VASC+ CS1 reduces the total burden of chemotherapy compared with surveillance or two courses of BEP. SWENOTECA currently recommends one course of BEP as standard treatment of VASC+ CS1 NSGCT, whereas both surveillance and one course of BEP are options for VASC- CS1 NSGCT.
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