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- Ekström, Magnus, et al.
(author)
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Exertional breathlessness related to medical conditions in middle-aged people: the population-based SCAPIS study of more than 25,000 men and women.
- 2024
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In: Respiratory research. - : BioMed Central (BMC). - 1465-993X .- 1465-9921. ; 25:1
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Journal article (peer-reviewed)abstract
- Breathlessness is common in the population and can be related to a range of medical conditions. We aimed to evaluate the burden of breathlessness related to different medical conditions in a middle-aged population.Cross-sectional analysis of the population-based Swedish CArdioPulmonary bioImage Study of adults aged 50-64years. Breathlessness (modified Medical Research Council [mMRC]≥2) was evaluated in relation to self-reported symptoms, stress, depression; physician-diagnosed conditions; measured body mass index (BMI), spirometry, venous haemoglobin concentration, coronary artery calcification and stenosis [computer tomography (CT) angiography], and pulmonary emphysema (high-resolution CT). For each condition, the prevalence and breathlessness population attributable fraction (PAF) were calculated, overall and by sex, smoking history, and presence/absence of self-reported cardiorespiratory disease.We included 25,948 people aged 57.5±[SD] 4.4; 51% women; 37% former and 12% current smokers; 43% overweight (BMI 25.0-29.9), 21% obese (BMI≥30); 25% with respiratory disease, 14% depression, 9% cardiac disease, and 3% anemia. Breathlessness was present in 3.7%. Medical conditions most strongly related to the breathlessness prevalence were (PAF 95%CI): overweight and obesity (59.6-66.0%), stress (31.6-76.8%), respiratory disease (20.1-37.1%), depression (17.1-26.6%), cardiac disease (6.3-12.7%), anemia (0.8-3.3%), and peripheral arterial disease (0.3-0.8%). Stress was the main factor in women and current smokers.Breathlessness mainly relates to overweight/obesity and stress and to a lesser extent to comorbidities like respiratory, depressive, and cardiac disorders among middle-aged people in a high-income setting-supporting the importance of lifestyle interventions to reduce the burden of breathlessness in the population.
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2. |
- Olsson, Max, et al.
(author)
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Factors important for health-related quality of life in men and women : The population based SCAPIS study
- 2023
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In: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 18:11
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Journal article (peer-reviewed)abstract
- IntroductionHealth-related quality of life (HRQoL) is essential for human wellbeing, influenced by a complex interplay of factors, and is reported lower in women than men. We aimed to evaluate which factors were the most important for HRQoL in a middle-aged general population.MethodsThis was a cross-sectional, multi-centre study of 29,212 men (48%) and women (52%) aged 50-64 in the general population in Sweden. Physical and mental HRQoL (0-100) was assessed using the Short Form 12 questionnaire, and association was evaluated for 356 variables including demographics, lifestyle, symptoms, physiological measurements, and health conditions. Using machine learning, each variable ' s importance for HRQoL was measured by an importance score, comparable to effect size, and summarised in 54 factors, in men and women separately.ResultsMen and women had similar mean and standard deviation (SD) scores for physical HRQoL (53.4 [SD 8.1] vs 51.4 [9.7]) and mental HRQoL (37.1 [5.0] vs 37.3 [5.4]). The most important factors for physical HRQoL were (importance score) physical activity (40), employment (36), pain (33), sleep (33), and sense of control (26). The most important factors for mental HRQoL were sense of control (18), physical activity (12), depression (12), pain (6), and employment (5).ConclusionsThe factors important for HRQoL identified by this study are likely to be amenable to interventions, and our findings can support prioritising interventions. The identified factors need to be a target even before middle-age to lay the foundation for long and happy lives.
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4. |
- Ekström, Anders, Professor, 1965-, et al.
(author)
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Conclusion
- 2022. - 1
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In: Times of History, Times of Nature. - New York & Oxford : Berghahn Books. - 9781800733237 - 9781800733350 ; , s. 334-339
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Book chapter (peer-reviewed)
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6. |
- Ekström, Anders, 1965-
(author)
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Den moderna krisens betydelse
- 2020
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In: Dagens Nyheter. - Stockholm. ; :28/5
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Journal article (pop. science, debate, etc.)
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9. |
- Ekström, Anders, Professor, 1965-
(author)
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Encountering the Geological Live : Temporalization in the Age of Natural Media
- 2022. - 1
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In: Times of History, Times of Nature. - New York & Oxford : Berghahn Books. - 9781800733237 - 9781800733350 ; , s. 308-333
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Book chapter (peer-reviewed)abstract
- As climate change becomes an increasingly important part of public discourse, the relationship between time in nature and history is changing. Nature can no longer be considered a slow and immobile background to human history, and the future can no longer be viewed as open and detached from the past. Times of History, Times of Nature engages with this historical shift in temporal sensibilities through a combination of detailed case studies and synthesizing efforts. Focusing on the history of knowledge, media theory, and environmental humanities, this volume explores the rich and nuanced notions of time and temporality that have emerged in response to climate change.
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10. |
- Ekström, Anders, Professor, 1965-
(author)
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Forging the Integrative Humanities : Policies and Prospects
- 2022. - 1
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In: The Humanities and the Modern Politics of Knowledge. - Amsterdam : Amsterdam University Press. - 9789463728867 - 9789048555024 ; , s. 275-289
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Book chapter (peer-reviewed)abstract
- Drawing on the results of this volume, this chapter reflects on the roleof the integrative humanities in contemporary knowledge policies. Itidentifies a long-standing tension in the history of the humanities between,on the one hand, an orientation toward integrative knowledge production,social responsiveness, and communication, and, on the other hand, amarginalizing tendency of reactive critique and disciplinary-bound selfreflection. The chapter situates the continuous relevance of this tensionin the context of three overlapping policy regimes, and the emergence ofa modern framework for policy work in Sweden in the last half-century.The chapter concludes by taking a more normative approach, arguing thata principal contribution of the humanities to contemporary knowledgepolitics lies in their public orientation
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