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- Andersson, Olle, 1964, et al.
(författare)
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Development and validation of a laryngopharyngeal reflux questionnaire, the Pharyngeal reflux Symptom Questionnaire
- 2010
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Ingår i: Scandinavian Journal of Gastroenterology. - 0036-5521. ; 45:2, s. 147-159
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To develop and validate the Pharyngeal Reflux Symptom Questionnaire (PRSQ), a comprehensive, disease-specific, self-administered questionnaire for laryngopharyngeal reflux (LPR) disease. MATERIAL AND METHODS: The PRSQ was developed based on empirical evidence from a literature review and expert input from physicians and patients and tested in a pilot study. In this validation study, a total of 228 patients were included and classified according to the Reflux Symptom Index (RSI) cut-off score. Patients with an RSI score > 13 were defined as abnormal, i.e. having LPR disease (n = 102), and those with a score between 0 and 13 were defined as normal controls (n = 126). Psychometric properties of the PRSQ were evaluated by exploring the factor structure and by evaluating internal consistency and item convergent and discriminant validity. Convergent and discriminant validity were determined by using the Laryngopharyngeal Reflux-Health Related Quality of Life questionnaire (LPR-HRQL), the RSI and the Short Form-36. RESULTS: The PRSQ was well accepted by the patients. Compliance was satisfactory and missing item rates were low. After item reduction, due to items not being conceptually relevant or scaling errors and/or low factor loadings, a construct was achieved with no scaling errors and high internal consistency (Cronbach's alpha 0.79-0.93). The correlations between the PRSQ and similar dimensions in the RSI and LPR-HRQL were generally strong. Discriminant validity was satisfactory as the questionnaire discriminated between patients with and without LPR disease. CONCLUSION: The PRSQ showed good psychometric properties and may become a valuable instrument for assessing LPR disease.
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| 2. |
- Andersson, Olle, 1964, et al.
(författare)
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Validation of the Swedish translation of LPR-HRQL.
- 2010
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Ingår i: Medical science monitor. - 1234-1010. ; 16:10, s. CR480-CR487
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: The aim of this study was to adapt the Laryngopharyngeal Reflux Health- Related Quality of Life questionnaire (LPR-HRQL) to Swedish and evaluate its psychometric properties in patients with suspected laryngopharyngeal reflux (LPR). MATERIAL/METHODS: The psychometric validation included 228 patients with suspected LPR who had previously undergone a 2-level 24-hour pH examination and who answered a mail-distributed set of questionnaires. The patients were divided into 2 comparable groups according to the Reflux Symptom Index (RSI) cut-off score: 126 patients with RSI score between 0-13 (defined as normal) and 102 patients with RSI score >13 (defined as abnormal, i.e. having LPR disease). RESULTS: LPR-HRQL was adapted to Swedish using a formal forward-backward translation method with input from expert groups (patients and physicians). Psychometric properties of the Swedish version of LPR-HRQL were evaluated by using factor analysis to explore the factor structure. Convergent and discriminant validity was determined by using the questionnaires RSI and Short Form-36 (SF-36). The psychometric tests performed fulfilled the criteria for structural integrity, validity and reliability, mostly confirming the results obtained in the original LPR-HRQL version. CONCLUSIONS: The Swedish translated version of LPR-HRQL proved to be a statistically valid instrument with which to assess HRQL in patients with LPR disease, and will be further tested in prospective studies.
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| 3. |
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| 4. |
- Carlsson, Sigrid, 1982, et al.
(författare)
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Validation of the Swedish M. D. Anderson Dysphagia Inventory (MDADI) in Patients with Head and Neck Cancer and Neurologic Swallowing Disturbances.
- 2012
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Ingår i: Dysphagia. - : Springer Science and Business Media LLC. - 1432-0460 .- 0179-051X. ; 27:3, s. 361-369
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Tidskriftsartikel (refereegranskat)abstract
- The aim of this study was to validate the Swedish version of the dysphagia-specific quality-of-life questionnaire, the M. D. Anderson Dysphagia Inventory (MDADI). Patients with oropharyngeal dysphagia due to neurologic disease (n=30) and head and neck (H&N) cancer patients with post-treatment subjective dysphagia (n=85) were compared to an age- and gender-matched nondysphagic control group (n=115). A formal forward-backward translation was performed and followed international guidelines. Validity and reliability were tested against the Short-Form 36 (SF-36) and Hospital Anxiety and Depression Scale (HADS). Internal-consistency reliability was calculated by means of Cronbach's α coefficient. Test-retest reliability was assessed by intraclass correlation (ICC). Convergent and discriminant validity were assessed by correlations between MDADI, SF-36, and HADS. Known-group validity was examined and statistically tested. Of 126 eligible patients, 115 agreed to participate (response rate=91.3%). The age of the participants ranged between 37 and 92 years. Most of the MDADI items showed good variability and only minor floor or ceiling effects in solitary items were found. The internal-consistency reliability (Cronbach's α) of the MDADI total score was 0.88 (after correction for systematic errors in the subjects' responses to two reversed questions). All estimates reached over the satisfactory >0.70 reliability standard for group-level comparison. ICC ranged between 0.83 and 0.97 in the test-retest. The mean MDADI total score was 66.9 (SD=14.7) for the H&N cancer patients, 65.0 (16.9) for the neurologic patients, and 97.5 (4.4) for the control group (P<0.001; study patients vs. controls). The MDADI was also sensitive to disease severity as measured by different food textures. The Swedish version of the MDADI showed good psychometric properties and is a valid instrument to assess dysphagia-related quality of life. It was also shown to be a reliable instrument after correction for systematic errors in the subjects' responses to two reversed questions. Its known-group validity enables the differentiation between dysphagic and nondysphagic patients for group-level research.
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| 6. |
- Eeg-Olofsson, Måns, 1967, et al.
(författare)
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Transmission of bone conducted sound – Correlation between hearing perception and cochlear vibration
- 2013
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Ingår i: Hearing Research. - : Elsevier. - 0378-5955 .- 1878-5891. ; 306, s. 11-20
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Tidskriftsartikel (refereegranskat)abstract
- The vibration velocity of the lateral semicircular canal and the cochlear promontory was measured on 16 subjects with a unilateral middle ear common cavity, using a laser Doppler vibrometer, when the stimulation was by bone conduction (BC). Four stimulation positions were used: three ipsilateral positions and one contralateral position. Masked BC pure tone thresholds were measured with the stimulation at the same four positions. Valid vibration data were obtained at frequencies between 0.3 and 5.0 kHz. Large intersubject variation of the results was found with both methods. The difference in cochlear velocity with BC stimulation at the four positions varied as a function of frequency while the tone thresholds showed a tendency of lower thresholds with stimulation at positions close to the cochlea. The correlation between the vibration velocities of the two measuring sites of the otic capsule was high. Also, relative median data showed similar trends for both vibration and threshold measurements. However, due to the high variability for both vibration and perceptual data, low correlation between the two methods was found at the individual level. The results from this study indicated that human hearing perception from BC sound can be estimated from the measure of cochlear vibrations of the otic capsule. It also showed that vibration measurements of the cochlea in cadaver heads are similar to that measured in live humans.
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| 7. |
- Finizia, Caterina, 1961, et al.
(författare)
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A Cross-sectional Validation Study of the Swedish Version of SWAL-QOL.
- 2012
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Ingår i: Dysphagia. - : Springer Science and Business Media LLC. - 0179-051X .- 1432-0460. ; 27:3, s. 325-335
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Tidskriftsartikel (refereegranskat)abstract
- The purpose of this study was to evaluate the psychometric properties of the Swedish version of the Swallowing Quality of Life questionnaire (SWAL-QOL). The study design was cross-sectional and the study was performed in patients with subjective oropharyngeal dysphagia due to head and neck (H&N) cancer (n=85) or neurological disease (n=30) and in a sample of age- and gender-matched controls (mean age=63years, 57% males) without subjective dysphagia (n=115). The Short-Form 36 (SF-36) and Hospital Anxiety and Depression Scale (HADS) questionnaires were used for assessment of convergent and discriminant validity. The Swedish version of SWAL-QOL was well accepted, the response rate was high (>90%), and the number of missing items were very low (<1%). Overall, the questionnaire showed good to excellent psychometric properties, including floor and ceiling effects (range=0-16 and 0-21%), internal consistency [Cronbach's α>0.70 for all domains except Eating Duration (0.69) and Sleep (0.68)], test-retest reliability (intraclass correlations=0.75-0.98) and convergent and discriminant validity as assessed by correlations between SWAL-QOL and SF-36 and HADS. SWAL-QOL also proved able to differentiate between dysphagic and nondysphagic patients (P<0.00001) (known-groups validity) and sensitive to disease severity as measured by different food textures.
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| 8. |
- Florentzson, Rut, 1957, et al.
(författare)
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Transmyringeal ventilation tube treatment: A 10-year cohort study.
- 2012
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Ingår i: International journal of pediatric otorhinolaryngology. - : Elsevier BV. - 1872-8464 .- 0165-5876. ; 76:8, s. 1117-22
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Tidskriftsartikel (refereegranskat)abstract
- Objective This ten-year cohort study was intended to determine the incidence and expected outcome of ventilation tube treatment at a clinic that serves a community with 300 000 inhabitants. Methods All children aged 0–10 years, who received their first ventilation tube during 1996, were followed over 10 years, at the department of Otorhinolaryngology, county hospital Ryhov, Jönköping, Sweden. All acute and planned visits were recorded and analyzed, but no extra visits were scheduled due to participation in the study. Results In 1996 the overall incidence of tube insertion in the age group 0–10 years was 1 percent. A total of 155 children were entered, and 146 (94 percent) fulfilled the study. During the 10 years’ follow up, a total of 409 acute visits and 1485 planned visits were made. In approximately 50 percent of the cases the first ventilation tube was still in place after one year. Infection occurred in 53 percent of the treated ear(s) at least once; the risk for infection was higher if the indication for ventilation tube placement was recurrent acute otitis media. In 45 percent of the children at least one more tube insertion was needed. A permanent perforation after tube treatment was seen in 2 percent of the treated ears. After 5 years, one half of the children were declared free from middle ear disease, but at the termination of the study 17 percent of the children were still in need of regular visits to an otologist due to residual ear problems. Conclusion This study shows the natural course of treatment with middle ear ventilation tubes in a cohort of children aged 0–10 years during a ten-year period. The incidence of ventilation tube treatment was 1 percent. It is evident that many children need a prolonged contact with an ear-nose and throat specialist when treated with a ventilation tube.
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| 10. |
- Johansson, Mia, 1977, et al.
(författare)
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"Setting boundaries" - Mental adjustment to cancer in laryngeal cancer patients: An interview study.
- 2012
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Ingår i: European journal of oncology nursing. - : Elsevier BV. - 1532-2122 .- 1462-3889. ; 16:4, s. 419-425
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: To increase the understanding of mental adjustment responses in laryngeal cancer patients, as well as the outcome of these responses. Further, to evaluate the content validity of the Swedish version of the Mini-MAC (Mental Adjustment to Cancer) Scale with regard to findings from the patient interviews. METHOD: Data was collected with semi-structured interviews and analyzed using a constant comparison technique consistent with Grounded Theory. Eighteen participants were selected according to the idea of theoretical sampling. RESULTS: The core category arising was "Setting boundaries". This seemed to be a prerequisite for mental adjustment to diagnosis and treatment without major negative impact on mental health or health-related quality of life (HRQL). Five descriptive categories also emerged: Fighting Spirit; Avoidance; Comparisons; Anxious Preoccupation; and Social Interactions. When comparing these results with the domains of the Mini-MAC Scale, the Fighting Spirit, Cognitive Avoidance and Anxious Preoccupation domains were clearly represented. Concerning the Fatalism and the Hopeless-Helpless domains the support was somewhat weaker. CONCLUSION: Central theme of mental adjustment responses in laryngeal cancer patients was "Setting Boundaries", concerning above all patients' attitude to information and thoughts about the cancer. This response seems to be the dividing line between good and poor adjustment. The results emphasize the importance of adapting the information given and rehabilitation options to each individual patient. The findings largely support the Swedish version of the Mini-MAC, but some deviations were found which should be considered when interpreting results from the Mini-MAC in laryngeal cancer patients.
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