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Träfflista för sökning "WFRF:(Gunnar W) srt2:(1980-1994)"

Sökning: WFRF:(Gunnar W) > (1980-1994)

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  • Kulatilake, P.H.S.W., et al. (författare)
  • Use of the distinct element method to perform stress analysis in rock with non-persistent joints and to study the effect of joint geometry parameters on the strength and deformability of rock masses
  • 1992
  • Ingår i: Rock Mechanics and Rock Engineering. - 0723-2632 .- 1434-453X. ; 25:4, s. 253-274
  • Tidskriftsartikel (refereegranskat)abstract
    • To use the distinct element method, it is necessary to discretize the problem domain into polygons in two dimensions (2 D) or into polyhedra in three dimensions (3 D). To perform distinct element stress analysis in a rock mass which contains non-persistent finite size joints, it is necessary to generate some type of fictitious joints so that when they are combined with the non-persistent joints, they discretize the problem domain into polygons in 2 D or into polyhedra in 3 D. The question arises as to which deformation and strength parameter values should be assigned to these fictitious joints so that they behave as intact rock. In this paper, linear elastic, perfectly-plastic constitutive models with the Mohr-Coulomb failure criterion, including a tension cut-off, were used to represent the mechanical behaviour of both intact rock and fictitious joints. It was found that, by choosing the parameter values for the constitutive models as given below, it is possible to make the fictitious joints behave as intact rock, in a global sense
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  • Midhagen, Gunnar, et al. (författare)
  • Adult coeliac disease within a defined area in Sweden : A study of prevalence and associated diseases
  • 1988
  • Ingår i: Scandinavian Journal of Gastroenterology. - : Informa UK Limited. - 0036-5521 .- 1502-7708. ; 23:8, s. 1000-1004
  • Tidskriftsartikel (refereegranskat)abstract
    • An epidemiologic study of coeliac disease in a geographically defined area of Sweden showed that the prevalence was 95.5/105 inhabitants aged 15 years or more. The highest prevalence, 178/105 inhabitants, was found in the age group 65-74 years. The lowest prevalence, 39/105 inhabitants, was found in patients aged 15-24 years. Among the associated diseases an especially high incidence of associated thyroid disease was observed: thyrotoxicosis occurred in 5.0% and hypothyroidism in 5.8% of the patients.
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  • O'Toole, Paul W., et al. (författare)
  • Two major classes in the M protein family in group A streptococci
  • 1992
  • Ingår i: Proceedings of the National Academy of Sciences. - 1091-6490. ; 89:18, s. 8661-8665
  • Tidskriftsartikel (refereegranskat)abstract
    • The M protein family of molecules in the group A streptococcus comprises a number of cell surface proteins that interact with the immune system of the host. One of the proteins in this family is the IgA receptor Arp4, which has C repeats similar to those that characterize the known M proteins. The streptococcal strain expressing Arp4 also expresses a second immunoglobulin-binding protein, Mrp4, which is shown here to be encoded by a gene located immediately upstream of the gene for Arp4. In addition to binding IgG, Mrp4 also binds fibrinogen, a property ascribed to M proteins. DNA sequence analysis demonstrated that the Mrp4 protein indeed is a member of the M protein family, but it was unexpectedly found to have a type of repeat that is identical to the A repeat described for FcRA76, a partially sequenced streptococcal Fc receptor. Purified FcRA76 was shown to bind fibrinogen and IgG, like Mrp4. These data show that the known molecules in the M protein family can be divided into two classes, A and C, according to the type of repeat region found. Hybridization studies with a panel of clinical isolates indicate that many streptococcal strains express class A and class C proteins, whereas some strains express only class C proteins. Class A molecules show amino-terminal sequence variation, like class C molecules, which suggests that proteins of both classes are targets for the immune response.
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