| 1. |
- Al-Adili, Ali, et al.
(författare)
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Fission Activities of the Nuclear Reactions Group in Uppsala
- 2015
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Ingår i: Scientific Workshop on Nuclear Fission Dynamics and the Emission of Prompt Neutrons and Gamma Rays, THEORY-3. - : Elsevier BV. ; , s. 145-149
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Konferensbidrag (refereegranskat)abstract
- This paper highlights some of the main activities related to fission of the nuclear reactions group at Uppsala University. The group is involved for instance in fission yield experiments at the IGISOL facility, cross-section measurements at the NFS facility, as well as fission dynamics studies at the IRMM JRC-EC. Moreover, work is ongoing on the Total Monte Carlo (TMC) methodology and on including the GEF fission code into the TALYS nuclear reaction code. Selected results from these projects are discussed.
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| 2. |
- Aldenlöv, Jens
(författare)
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Exploring Public Procurement of Swedish Railway Infrastructure Maintenance
- 2019
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Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
- In 2002, Sweden started to outsource its railway infrastructure maintenance. Through gradual exposure (i.e. outsourcing one contract area at a time), the Swedish Transport Administration has developed its competence of being a client towards its contractors. The last contract was outsourced in 2014. In the last decade, the development of governance techniques and maintenance cost has not matched the increase in traffic. Due to an increased awareness in environmentally friendlier transportation, traffic is only expected to increase further in the coming years. Governance techniques and maintenance cost ultimately depends on the client-contractor relationship through public procurement. Hence, there is a need to understand public procurement of railway infrastructure maintenance. Therefore, the purpose of this thesis is to contribute to the knowledge of public procurement of railway infrastructure maintenance. Three separate studies were conducted. Study 1 was a literature review to explore and determine the state-of-the-art for the field of public procurement of railway maintenance. Study 2 was a linear regression analysis to examine the relationship between contract design and the output of maintenance in Sweden. Study 3 was an interview study in Sweden that explored what factors that supports or hinders collaboration in railway maintenance.The main results of these studies are that asset knowledge is important for both the client and the contractor. Through reliable asset knowledge, incentives and contracts can be designed to support governance and collaboration. Today, railway infrastructure maintenance is dominated by informal relationships that lack the support of formal partnering activities. When an informal relationship is supported by a formal structure it provides a basis for innovation. This formal structure should be centralized around gaining and sharing asset knowledge. By establishing such a system to increase the asset knowledge and supporting collaboration, public organizations of maintenance can provide a basis for the improvement of maintenance.
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| 3. |
- Alhassan, Erwin, et al.
(författare)
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Uncertainty analysis of Lead cross sections on reactor safety for ELECTRA
- 2016
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Ingår i: SNA + MC 2013 - Joint International Conference on Supercomputing in Nuclear Applications + Monte Carlo. - Les Ulis, France : EDP Sciences.
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Konferensbidrag (refereegranskat)abstract
- The Total Monte Carlo (TMC) method was used in this study to assess the impact of Pb-206, 207 and 208 nucleardata uncertainties on k-eff , beta-eff, coolant temperature coefficient, the coolant void worth for the ELECTRA reactor. Relatively large uncertainties were observed in the k-eff and the coolant void worth for all the isotopes with significant contribution coming from Pb-208 nuclear data. The large Pb-208 nuclear data uncertainty observed was further investigated by studying the impact of partial channels on the k-eff and beta-eff. Various sections of ENDF file: elasticscattering (n,el), inelastic scattering (n,inl), neutron capture (n,gamma), (n,2n), resonance parameters and the angular distribution were varied randomly and distributions in k-eff and beta-eff obtained. The dominant contributions to the uncertainty in the k-eff from Pb-208 came from uncertainties in the resonance parameters; however, elastic scattering cross section and the angular distribution also had significant impact. The impact of nuclear data uncertainties on the beta-eff was observed to be small.
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| 6. |
- Chen, Yen Hsi, et al.
(författare)
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The GAGOme : a cell-based library of displayed glycosaminoglycans
- 2018
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Ingår i: Nature Methods. - : Springer Science and Business Media LLC. - 1548-7091 .- 1548-7105. ; 15:11, s. 881-888
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Tidskriftsartikel (refereegranskat)abstract
- Glycosaminoglycans (GAGs) are essential polysaccharides in normal physiology and disease. However, understanding of the contribution of specific GAG structures to specific biological functions is limited, largely because of the great structural heterogeneity among GAGs themselves, as well as technical limitations in the structural characterization and chemical synthesis of GAGs. Here we describe a cell-based method to produce and display distinct GAGs with a broad repertoire of modifications, a library we refer to as the GAGOme. By using precise gene editing, we engineered a large panel of Chinese hamster ovary cells with knockout or knock-in of the genes encoding most of the enzymes involved in GAG biosynthesis, to generate a library of isogenic cell lines that differentially display distinct GAG features. We show that this library can be used for cell-based binding assays, recombinant expression of proteoglycans with distinct GAG structures, and production of distinct GAG chains on metabolic primers that may be used for the assembly of GAG glycan microarrays.
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| 7. |
- Gustavsson, Carolina, et al.
(författare)
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Cerebrospinal fluid levels of insulin, leptin, and agouti-related protein in relation to BMI in pregnant women
- 2016
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Ingår i: Obesity. - : Wiley. - 1930-7381. ; 24:6, s. 1299-1304
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Tidskriftsartikel (refereegranskat)abstract
- ObjectiveDuring pregnancy, metabolic interactions must be adapted, though neuroendocrine mechanisms for increased food intake are poorly understood. The objective of this study was to characterize differences in insulin, leptin, and agouti-related protein (AgRP) levels in serum and cerebrospinal fluid (CSF) in pregnant women with normal weight (NW) and pregnant women with overweight (OW) or obesity (OB). Placenta as a source for increased peripheral AgRP levels during pregnancy was also investigated. MethodsWomen were recruited at admission for elective cesarean section. Insulin, AgRP, and leptin were measured in serum and CSF from 30 NW, 25 OW, and 21 OB at term. Serum during pregnancy and placenta at term were collected for further AgRP analysis. ResultsImmunohistology showed placental production of AgRP and serum AgRP levels increased throughout pregnancy. CSF AgRP, leptin, and insulin levels were higher in OW and OB than NW. Serum leptin and insulin levels were higher and AgRP lower in OB than NW. ConclusionsHigh serum AgRP levels might protect from the suppressive effects of leptin during pregnancy. Pregnant women with OB and OW might further be protected from the suppressive effect of leptin by high CSF AgRP levels. Evidence was found, for the first time, of human placental AgRP production mirrored by levels in the circulation.
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| 8. |
- Gustavsson, Henrik, et al.
(författare)
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Continuous assessment in software engineering project course using publicly available data from GitHub
- 2019
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Ingår i: Proceedings of the 15th International Symposium on Open Collaboration, OpenSym 2019. - New York, NY, USA : Association for Computing Machinery (ACM). - 9781450363198
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Konferensbidrag (refereegranskat)abstract
- This paper describes an approach for assessment in a large software engineering project course. We propose an approach for continuously collecting information from a source code repository and collaboration tool, and using this information for assessing student contributions and also for assessing the course as a whole from the teacher's standpoint. We present how we display metrics for how the students perform in relation to some of the requirements of the course. We argue that continuous summative assessment feedback to the students on how they are performing in the project is a suitable strategy for ensuring active participation from the students for the duration of the project course.
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| 9. |
- Gustavsson, Jakob, et al.
(författare)
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Screening of replacement substances for the brominated flame retardants PBDE, HBCDD and TBBPA
- 2018
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Målet med projektet var att identifiera akvatiska punktkällor för flamskyddsmedel (FRs) till den svenska miljön. Detta gjordes genom att mäta halter i olika typer av vattenflöden och beräkna dagliga flöden av FRs med hjälp av vattenmassaflöden. De verksamheter som undersöktes inkluderade avloppsreningsverk (n = 5), avfallsanläggningar (n = 4), flygplatser (n = 5), industrier (n = 2), dagvatten från stads/industriområden (n = 6) samt lantbruk (n = 2). Vatten- (n = 42) och partikelprover (n = 42) samlades in under februari-april 2018 och analyserades för totalt 62 olika FRs från tre olika ämnesklasser: halogenerade FRs (HFRs), organofosfater (OPFRs) och polybromerade difenyletrar (PBDEs).Totalt detekterades 34 olika FRs i minst ett prov. Flest antal olika FRs hittades i provet från en avfallsanläggning (Högbytorp; n = 23), följt av Skavsta flygplats (n = 17), Ärna flygplats (n = 16) och Ryaverket avloppsreningsverk (n = 16). I genomsnitt hittades flest flamskyddsmedel vid avfallsanläggningar (n = 15 ± 5), följt av avloppsreningsverk (n = 13 ± 3), dagvatten (n = 11 ± 2), flygplatser (n = 9 ± 6) och industri (n = 5 ± 1). TDCIPP var det FR som detekterades i flest antal prover (78 % av alla prover), följt av BDE66 (68 %), TEHP (57 %), TCIPP (57 %) och TBOEP (57 %).Den totala halten FRs i proverna varierade mellan De beräknade flödena av FRs varierade mellan
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| 10. |
- Gustavsson, Karin, et al.
(författare)
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Runda hörn och en obemärkt forskare
- 2016
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Ingår i: Vetenskapssociteten i Lund : Årsbok 2016 - Årsbok 2016. - 0349-053X. - 9789198055160 ; , s. 21-39
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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