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- Kramer, Elissa L., et al.
(författare)
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CT-SPECT fusion to correlate radiolabeled monoclonal antibody uptake with abdominal CT findings
- 1989
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Ingår i: Radiology. - : American College of Radiology. - 0033-8419 .- 1527-1315. ; 172:3, s. 861-865
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Tidskriftsartikel (refereegranskat)abstract
- To enhance the information provided by computed tomography {(CT)} and single photon emission computed tomography {(SPECT)} performed with radiolabeled, anti-carcinoembryonic antigen monoclonal antibody {(MoAb)}, the authors performed fusion of these types of images from eight subjects with suspected colorectal adenocarcinoma. Section thickness and pixel size of the two studies were matched, coordinates of corresponding points from each study were identified, and {CT} sections were translated, rotated, and reprojected to match the corresponding {SPECT} scans. The {CT-SPECT} fusion enabled identification of anatomic sites of tumor-specific {MoAb} accumulation in four cases, showed non-specific {MoAb} accumulation in two, and helped confirm information only suggested by the two studies separately in one.
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