| 1. |
- Ridderstad, Per S, et al.
(författare)
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The white library of the red rose : Petr Wok z Rozmberka (1539-1611) and his library
- 2003
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Ingår i: Actes et comunications = Transactions / Association Internationale de bibliophilie = International Association of Bibliophily, XIX congrès, Prague, 1995. - 8495241285
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- A recapitulation of the history of the the great library of the Bohemian statesman Peter Wok Rosenberg, which after his death entered the Emporor’s treasures in Prague, but was captured by the Swedish Army at the end of the Thirty Years War and brought to Stockholm, where parts still reside in the Royal Library. Its white bindings are a prominent feature of the Rosenberg collection.
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| 2. |
- Sindi, Shireen, et al.
(författare)
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Midlife work-related stress is associated with late-life cognition
- 2017
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Ingår i: Journal of Neurology. - : Springer Science and Business Media LLC. - 0340-5354 .- 1432-1459. ; 264:9, s. 1996-2002
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Tidskriftsartikel (refereegranskat)abstract
- To investigate the associations between midlife work-related stress and late-life cognition in individuals without dementia from the general population. The Cardiovascular Risk Factors, Aging and Dementia (CAIDE) study population (n = 2000) was randomly selected from independent Finnish population-based surveys (baseline mean age 50 years). Participants underwent two re-examinations in late life (mean age 71 and 78 years, respectively). 1511 subjects participated in at least one re-examination (mean total follow-up 25 years). Work-related stress was measured using two questions on work demands administered in midlife. Multiple cognitive domains were assessed. Analyses were adjusted for several potential confounders. Higher levels of midlife work-related stress were associated with poorer performance on global cognition [beta-coefficient, -0.02; 95% confidence interval (CI), -0.05 to -0.00], and processing speed [beta -0.03, CI -0.05 to -0.01]. Results remained significant after adjusting for potential confounders. Work-related stress was not significantly associated with episodic memory, executive functioning, verbal fluency or manual dexterity. This study shows that global cognition and processing speed may be particularly susceptible to the effects of midlife work-related stress.
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| 3. |
- Mirzanamadi, Raheb, 1987, et al.
(författare)
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Numerical Investigation of Anti-Icing Road Surfaces using Hydronic Heating Pavement- Parametric Study
- 2019
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Ingår i: Building Simulation Conference Proceedings. - : IBPSA. - 2522-2708. - 9781713809418 ; 16, s. 425-431
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Konferensbidrag (refereegranskat)abstract
- An environmental friendly method to mitigate the slippery condition on road surfaces is to use a Hydronic Heating Pavement (HHP). The performance of the HHP system strongly depends on its design parameters. The aim of this study is to investigate the effects of different design parameters of the HHP system on the anti-icing operation of the road surface. A hybrid 3D numerical simulation model of HHP system is used to simulate the anti-icing operation. The numerical model is validated by an analytical solution. The validation result shows that the maximum relative error associated with the temperature decline along the pipe is less than 3% between the obtained results from the numerical simulation model and the analytical solution. The results show that the distance between pipes has the most significant effect on improving the anti-icing operation, so changing the distance from 400 mm to 50 mm resulted in a 90% decrease in the remaining number of hours of the slippery conditions on the road surface. The order of parameters, investigated in this study, associated with shortening the number of hours of the slippery condition on the road surface is: (i) the distance between the pipes, (ii) the fluid flow rate, (iii) the inlet temperature of fluid, (iv) the embedded depth of the pipe and (v) the pipe diameter.
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| 4. |
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| 5. |
- Sindi, S., et al.
(författare)
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Sex differences in dementia and response to a lifestyle intervention: Evidence from Nordic population-based studies and a prevention trial
- 2021
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Ingår i: Alzheimers & Dementia. - : Wiley. - 1552-5260 .- 1552-5279. ; 17:7, s. 1166-1178
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Tidskriftsartikel (refereegranskat)abstract
- Introduction Evidence on sex differences in the risk for dementia has been mixed. The goal was to assess sex differences in the development of dementia, and in the effects of a lifestyle intervention. Methods Two strategies were adopted, one using combined data from three large Nordic population-based cohort studies (n = 2289), adopting dementia as outcome, and 2-year multidomain lifestyle intervention (n = 1260), adopting cognitive change as outcome. Results There was higher risk for dementia after age 80 years in women. The positive effects of the lifestyle intervention on cognition did not significantly differ between men and women. Sex-specific analyses suggested that different vascular, lifestyle, and psychosocial risk factors are important for women and men in mid- and late-life. Conclusion Women had higher risk for dementia among the oldest individuals. Lifestyle interventions may be effectively implemented among older men and women.
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| 7. |
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| 8. |
- Nguyen, James, 1989-
(författare)
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Confidence in Covid-19 models
- 2024
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Ingår i: Synthese. - 0039-7857 .- 1573-0964. ; 203:4
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Tidskriftsartikel (refereegranskat)abstract
- Epidemiological models of the transmission of SARS-CoV-2 played an important role in guiding the decisions of policy-makers during the pandemic. Such models provide output projections, in the form of time -series of infections, hospitalisations, and deaths, under various different parameter and scenario assumptions. In this paper I caution against handling these outputs uncritically: raw model-outputs should not be presented as direct projections in contexts where modelling results are required to support policy -decisions. I argue that model uncertainty should be handled and communicated transparently. Drawing on methods used by climate scientists in the fifth IPCC report I suggest that this can be done by: attaching confidence judgements to projections based on model results; being transparent about how multi-model ensembles are supposed to deal with such uncertainty; and using expert judgement to 'translate' model-outputs into projections about the actual world. In a slogan: tell me what you think (and why), not (just) what your models say. I then diffuse the worry that this approach infects model-based policy advice with some undesirably subjective elements, and explore how my discussion fares if one thinks the role of a scientific advisor is to prompt action, rather than communicate information.
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| 9. |
- Nocchi, Sarah, et al.
(författare)
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Electrochemical monitoring of native catalase activity in skin using skin covered oxygen electrode
- 2017
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Ingår i: Biosensors & bioelectronics. - : Elsevier. - 0956-5663 .- 1873-4235. ; 93, s. 9-13
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Tidskriftsartikel (refereegranskat)abstract
- A skin covered oxygen electrode, SCOE, was constructed with the aim to study the enzyme catalase, which is part of the biological antioxidative system present in skin. The electrode was exposed to different concentrations of H2O2 and the amperometric current response was recorded. The observed current is due to H2O2 penetration through the outermost skin barrier (referred to as the stratum corneum, SC) and subsequent catalytic generation of O2 by catalase present in the underlying viable epidermis and dermis. By tape-stripping the outermost skin layers we demonstrate that SC is a considerable diffusion barrier for H2O2 penetration. Our experiments also indicate that skin contains a substantial amount of catalase, which is sufficient to detoxify H2O2 that reaches the viable epidermis after exposure of skin to high concentrations of peroxide (0.5–1 mM H2O2). Further, we demonstrate that the catalase activity is reduced at acidic pH, as compared with the activity at pH 7.4. Finally, experiments with often used penetration enhancer thymol shows that this compound interferes with the catalase reaction. Health aspect of this is briefly discussed. Summarizing, the results of this work show that the SCOE can be utilized to study a broad spectrum of issues involving the function of skin catalase in particular, and the native biological antioxidative system in skin in general.
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| 10. |
- Lind, Ingela, 1975-
(författare)
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Regressor and Structure Selection : Uses of ANOVA in System Identification
- 2006
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Identification of nonlinear dynamical models of a black box nature involves both structure decisions (i.e., which regressors to use and the selection of a regressor function), and the estimation of the parameters involved. The typical approach in system identification is often a mix of all these steps, which for example means that the selection of regressors is based on the fits that is achieved for different choices. Alternatively one could then interpret the regressor selection as based on hypothesis tests (F-tests) at a certain confidence level that depends on the data. It would in many cases be desirable to decide which regressors to use, independently of the other steps. A survey of regressor selection methods used for linear regression and nonlinear identification problems is given.In this thesis we investigate what the well known method of analysis of variance (ANOVA) can offer for this problem. System identification applications violate many of the ideal conditions for which ANOVA was designed and we study how the method performs under such non-ideal conditions. It turns out that ANOVA gives better and more homogeneous results compared to several other regressor selection methods. Some practical aspects are discussed, especially how to categorise the data set for the use of ANOVA, and whether to balance the data set used for structure identification or not.An ANOVA-based method, Test of Interactions using Layout for Intermixed ANOVA (TILIA), for regressor selection in typical system identification problems with many candidate regressors is developed and tested with good performance on a variety of simulated and measured data sets.Typical system identification applications of ANOVA, such as guiding the choice of linear terms in the regression vector and the choice of regime variables in local linear models, are investigated.It is also shown that the ANOVA problem can be recast as an optimisation problem. Two modified, convex versions of the ANOVA optimisation problem are then proposed, and it turns out that they are closely related to the nn-garrote and wavelet shrinkage methods, respectively. In the case of balanced data, it is also shown that the methods have a nice orthogonality property in the sense that different groups of parameters can be computed independently.
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