| 1. |
- Weinstein, John N., et al.
(författare)
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The cancer genome atlas pan-cancer analysis project
- 2013
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Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 45:10, s. 1113-1120
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Forskningsöversikt (refereegranskat)abstract
- The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. The resulting rich data provide a major opportunity to develop an integrated picture of commonalities, differences and emergent themes across tumor lineages. The Pan-Cancer initiative compares the first 12 tumor types profiled by TCGA. Analysis of the molecular aberrations and their functional roles across tumor types will teach us how to extend therapies effective in one cancer type to others with a similar genomic profile. © 2013 Nature America, Inc. All rights reserved.
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| 2. |
- Li, Jiantong, et al.
(författare)
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Ink-jet printed thin-film transistors with carbon nanotube channels shaped in long strips
- 2011
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Ingår i: Journal of Applied Physics. - : AIP Publishing. - 0021-8979 .- 1089-7550. ; 109:8, s. 084915-
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Tidskriftsartikel (refereegranskat)abstract
- The present work reports on the development of a class of sophisticated thin-film transistors (TFTs) based on ink-jet printing of pristine single-walled carbon nanotubes (SWCNTs) for the channel formation. The transistors are manufactured on oxidized silicon wafers and flexible plastic substrates at ambient conditions. For this purpose, ink-jet printing techniques are developed with the aim of high-throughput production of SWCNT thin-film channels shaped in long strips. Stable SWCNT inks with proper fluidic characteristics are formulated by polymer addition. The present work unveils, through Monte Carlo simulations and in light of heterogeneous percolation, the underlying physics of the superiority of long-strip channels for SWCNT TFTs. It further predicts the compatibility of such a channel structure with ink-jet printing, taking into account the minimum dimensions achievable by commercially available printers. The printed devices exhibit improved electrical performance and scalability as compared to previously reported ink-jet printed SWCNT TFTs. The present work demonstrates that ink-jet printed SWCNT TFTs of long-strip channels are promising building blocks for flexible electronics.
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| 3. |
- Cho, Yoon Shin, et al.
(författare)
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Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians.
- 2012
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Ingår i: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 44:1
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Tidskriftsartikel (refereegranskat)abstract
- We conducted a three-stage genetic study to identify susceptibility loci for type 2 diabetes (T2D) in east Asian populations. We followed our stage 1 meta-analysis of eight T2D genome-wide association studies (6,952 cases with T2D and 11,865 controls) with a stage 2 in silico replication analysis (5,843 cases and 4,574 controls) and a stage 3 de novo replication analysis (12,284 cases and 13,172 controls). The combined analysis identified eight new T2D loci reaching genome-wide significance, which mapped in or near GLIS3, PEPD, FITM2-R3HDML-HNF4A, KCNK16, MAEA, GCC1-PAX4, PSMD6 and ZFAND3. GLIS3, which is involved in pancreatic beta cell development and insulin gene expression, is known for its association with fasting glucose levels. The evidence of an association with T2D for PEPD and HNF4A has been shown in previous studies. KCNK16 may regulate glucose-dependent insulin secretion in the pancreas. These findings, derived from an east Asian population, provide new perspectives on the etiology of T2D.
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| 4. |
- Feng, Yi, et al.
(författare)
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Electrical and humidity-sensing characterization of inkjet-printed multi-walled carbon nanotubes for smart packaging
- 2013
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Ingår i: IEEE SENSORS 2013 - Proceedings. - : IEEE. - 9781467346405 ; , s. 1-4
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Konferensbidrag (refereegranskat)abstract
- Printing is considered a cost-effective way to fabricate electronics on unconventional substrates enabling, for example, smart packaging. Functionalized multi-walled carbon nanotubes (f-MWCNTs) having carboxylic groups on their surfaces possess great potential as flexible resistive humidity sensor. In this paper, we report on the inkjet printing and characterization of f-MWCNTs in terms of sheet resistance and humidity-sensitivity. Stable f-MWCNTs ink is formulated using aqueous ethylene glycol as solvent. Sheet resistance of printed f-MWCNTs films on polyimide foil reduces by increasing the number of printed layers as well as post-printing annealing temperature. Meanwhile, the raised annealing temperature degrades the films' humidity-sensitivity, which could be explained by the loss of the carboxylic groups. The electrical and sensing properties of f-MWCNTs also have a negative temperature coefficient regarding ambient temperature, which should be considered in practical application.
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| 5. |
- Feng, Yi, et al.
(författare)
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Fabrication and performance evaluation of ultralow-cost inkjet-printed chipless RFID tags
- 2012
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Konferensbidrag (refereegranskat)abstract
- This paper studies the performance of inkjet-printed chipless RFID tags based on planar inductor-capacitor resonant circuits. Besides using double-sided printing, a sandwiching process is introduced to fabricate the tags in order to eliminate the need of through-substrate via and match roll-to-roll processing. Due to lower conductivity (~1.25E+7 S/m) and smaller thickness (~1.7μm) of printed conductors with silver nanoparticle ink, the resonant peaks of inkjet-printed tags exhibit around as twice of half-power bandwidth and 60% of maximum reading distance as the etched tags from bulk copper. Nevertheless, the inkjet-printed tag performance is sufficient for many applications, and it can be adjusted and improved by printing and sintering processes.
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| 6. |
- Mäntysalo, Matti, et al.
(författare)
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System integration of smart packages using printed electronics
- 2012
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Ingår i: Electronic Components and Technology Conference (ECTC), 2012 IEEE 62nd. - : IEEE. - 9781467319669 ; , s. 997-1002
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Konferensbidrag (refereegranskat)abstract
- The last decade has shown enormous interest in additive and printed electronics manufacturing technologies, especially in intelligent packaging. Scientists and engineers all over the world are developing printed organic circuits. Despite their effort, the performance and yield of all-printed devices cannot replace silicon-based devices in smart package applications. Therefore, we have developed a hybrid interconnection platform to seamlessly integrate printed electronics with silicon-based electronics, close the gap between the two technologies, and to anticipate adaption of printed electronic technologies. We studied the suitability of a printed interconnection platform by fabricating a printed sensor-box that contains printed nano-Ag-interconnections on low-temperature plastic, a printable humidity sensor based on functionalized MWCNTs, a printed battery, conventional SMDs, and a silicon-based MCU.
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| 7. |
- Xie, Li, et al.
(författare)
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Electrical performance and reliability evaluation of inkjet-printed Ag interconnections on paper substrates
- 2012
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Ingår i: Materials letters (General ed.). - : Elsevier BV. - 0167-577X .- 1873-4979. ; 88, s. 68-72
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Tidskriftsartikel (refereegranskat)abstract
- Printing technology, especially inkjet printing, enables mass manufacturing of electronics on various substrate materials. Paper is one potential carrier for printed electronics to realize low-cost, flexible, recyclable smart packages. However, concerns exist regarding commonly used photo paper substrate, in terms of price and reliability against environmental variation. In this work, for the first time, ordinary low-cost and high-moisture-resistance package paper is investigated as an alternative to be the substrate of printed electronics. The surface morphology and electrical performance of inkjet printed interconnections on six different paper substrates from two categories (inkjet paper and package paper) are examined and compared. The printed interconnections on inkjet papers show smaller sheet resistance and better repeatability than those on package papers. However, low-cost package paper stands higher temperature and exhibits better reliability during 85°C/85 RH aging test. Package paper is suitable for smart package applications that have relaxed requirements of conductivity and high requests of moisture resistance.
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| 8. |
- Xie, Li, et al.
(författare)
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Integration of f-MWCNT Sensor and Printed Circuits on Paper Substrate
- 2013
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Ingår i: IEEE Sensors Journal. - 1530-437X .- 1558-1748. ; 13:10, s. 3948-3956
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Tidskriftsartikel (refereegranskat)abstract
- The integration of sensors endows the packages with intelligence and interactivity. This paper is considered the most suitable substrate of smart packages because it is cost-effective, light, flexible, and recyclable. However, common concern exists regarding the reliability of paper-based system against bending and folding. In this paper, inkjet-printing of silver nanoparticles is used to form circuit pattern as well as interconnections for system integration on paper substrate. A humidity sensor made by functionalized multiwalled carbon nanotubes is fabricated on the same substrate. We evaluate the electrical performance of paper electronics and the reliability against bending and folding. The results reveal the capability and the limitation of paper electronics in terms of flexibility. The concept of a paper-based smart electronic system and the manufacture process are demonstrated by an interactive humidity sensor card prototype.
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| 9. |
- Feng, Yi, et al.
(författare)
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Characterization of Inkjet Printed Coplanar Waveguides for Flexible Electronics
- 2011
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Ingår i: NIP27: International Conference on Digital Printing Technologies and Digital Fabrication 2011. - : The Society for Imaging Science and Technology. - 9780892082964 ; , s. 454-457
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Konferensbidrag (refereegranskat)abstract
- The low conductivity and thin layers of the inkjet-printed metal conductors have always been a big concern in paper-based printed electronics for high frequency applications. To provide the fundamental knowledge, the high frequency characteristics of inkjet-printed coplanar waveguides on paper substrate were studied experimentally in terms of characteristic impedance and conductor losses using the time domain reflectometry technique. The influences of different printing settings and of geometric parameters on the waveguide's properties were investigated. Considering the measurement accuracy in high frequency characterization, one sample with an impedance of 51.2Ω was achieved. The electrical stability of the samples was also studied and explained. In addition, one waveguide sample was printed in a way that the pattern area with the highest current density is thickened. This variable ink-layer thickness approach has successfully been proven as a promising solution to reduce the conductor losses and yet consuming less ink.
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| 10. |
- Feng, Yi, et al.
(författare)
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Design of a Printable Multi-Functional Sensor for Remote Monitoring
- 2011
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Ingår i: 2011 IEEE SENSORS Proceedings. - : IEEE Sensors Council. - 9781424492893 ; , s. 675-678
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Konferensbidrag (refereegranskat)abstract
- This paper proposes a novel printable multi-functional passive sensor for remote monitoring. The sensor mainly consists of a series of pairs of transmission lines and sensing resistors whose resistances vary with one physical parameter. A short-duration radio-frequency pulse as interrogation signal travels along the transmission line and is partially reflected at each resistor due to impedance mismatch. By measuring the energies of the discrete reflected pulses in time domain, all the physical parameters could be detected simultaneously. This design not only saves complex circuitry but also enables easy adaptation for detecting multiple parameters. We have theoretically analyzed the sensor assuming it has an arbitrary number of sensing resistors. The introduced algorithm between the pulse energies and resistances is verified by simulation. As a prototype, an inkjet-printed sensor on polyimide foil is presented. The experimental measurement has successfully proven the design concept.
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