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Enumeration	Reference	Cover	Find
1.	2017 swepub:Mat__t
2.	McHugh, DMS, et al. (author) Clinical validation of cutoff target ranges in newborn screening of metabolic disorders by tandem mass spectrometry: a worldwide collaborative project 2011 In: Genetics in medicine : official journal of the American College of Medical Genetics. - 1530-0366. ; 13:3, s. 230-254 Journal article (peer-reviewed)
3.	Law, ZK, et al. (author) Brief Consent Methods Enable Rapid Enrollment in Acute Stroke Trial: Results From the TICH-2 Randomized Controlled Trial 2022 In: Stroke. - 1524-4628. ; 53:4, s. 1141-1148 Journal article (peer-reviewed)
4.	Law, ZK, et al. (author) Brief Consent Methods Enable Rapid Enrollment in Acute Stroke Trial: Results From the TICH-2 Randomized Controlled Trial 2022 In: Stroke. - 1524-4628. ; 53:4, s. 1141-1148 Journal article (peer-reviewed)
5.	Ellis, Gemma L, et al. (author) Two-Step synthesis of Achiral Dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles 2008 In: Journal of Medicinal Chemistry. - : American Chemical Society (ACS). - 0022-2623 .- 1520-4804. ; 51:7, s. 2170-2177 Journal article (peer-reviewed)abstract A rapid, two step synthesis of a range of dispiro-1,2,4,5-tetraoxanes with potent antimalarial activity both in vitro and in vivo has been achieved. These 1,2,4,5-tetraoxanes have been proven to be superior to 1,2,4-trioxolanes in terms of stability and to be superior to trioxane analogues in terms of both stability and activity. Selected analogues have in vitro nanomolar antimalarial activity, good oral activity and are non-toxic in screens for both cytotoxicity and genotoxicity. The synthesis of a fluorescent NBD-tagged tetraoxane probe has allowed investigation into the mechanism of accumulation of these drugs using laser scanning confocal microscopy techniques.

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Type of publication: journal article (4)

Type of content: peer-reviewed (4)

Author/Editor: Chen, C. (1); Chen, S. (1); Chen, X. (1); Chen, Y. (1); Deluca, C. (1); Endo, M. (1); show more...; Garcia, C. (1); Hayashi, T. (1); Hirose, M. (1); Hu, D. (1); Jackson, M. (1); Kim, H. (1); Kobayashi, T. (1); Li, B. (1); Li, L. (1); Liu, B. (1); Liu, D. (1); Liu, L. (1); Nakamura, T. (1); Ninomiya, Y. (1); Okumura, Y. (1); Sanchez, J. (1); Sasaki, Y. (1); Shimizu, S. (1); Sun, X. (1); Suzuki, Y. (1); Takahashi, Y. (1); Tanaka, S. (1); Vogel, M. (1); Wang, C. (1); Wang, F. (1); Wang, R. (1); Wu, X. (1); Yamamoto, S. (1); Yang, H. (1); Yang, Y. (1); Zhang, J. (1); Zhu, J. (1); Zhu, Y. (1); Kim, Y. (1); Zhang, R. (1); Zhao, Y. (1); Banerjee, P. (1); Gosselink, M. (1); Kanno, T. (1); Watanabe, I. (1); Gonzalez, S. (1); Suzuki, S (1); Banerjee, S. (1); Rodriguez, D. (1); show less...

University: Karolinska Institutet (4); Mid Sweden University (1)

Language: English (5)

Research subject (UKÄ/SCB): Natural sciences (1)

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