SwePub
Sök i SwePub databas

  Utökad sökning

Träfflista för sökning "WFRF:(Verberk Janneke D M) srt2:(2023)"

Sökning: WFRF:(Verberk Janneke D M) > (2023)

  • Resultat 1-2 av 2
Sortera/gruppera träfflistan
   
NumreringReferensOmslagsbildHitta
1.
  • Venniro, Marco, et al. (författare)
  • Improving translation of animal models of addiction and relapse by reverse translation
  • 2020
  • Ingår i: Nature Reviews Neuroscience. - : NATURE RESEARCH. - 1471-003X .- 1471-0048. ; 21:11, s. 625-643
  • Forskningsöversikt (refereegranskat)abstract
    • Critical features of human addiction are increasingly being incorporated into complementary animal models, including escalation of drug intake, punished drug seeking and taking, intermittent drug access, choice between drug and non-drug rewards, and assessment of individual differences based on criteria in the fourth edition of theDiagnostic and Statistical Manual of Mental Disorders(DSM-IV). Combined with new technologies, these models advanced our understanding of brain mechanisms of drug self-administration and relapse, but these mechanistic gains have not led to improvements in addiction treatment. This problem is not unique to addiction neuroscience, but it is an increasing source of disappointment and calls to regroup. Here we first summarize behavioural and neurobiological results from the animal models mentioned above. We then propose a reverse translational approach, whose goal is to develop models that mimic successful treatments: opioid agonist maintenance, contingency management and the community-reinforcement approach. These reverse-translated treatments may provide an ecologically relevant platform from which to discover new circuits, test new medications and improve translation. Recent advances in animal addiction models have emphasized translational challenges. In this Review, Venniro and colleagues introduce a reverse translational approach that may provide an ecologically relevant platform from which to discover new circuits, test new medications and improve translation.
  •  
2.
  • Davari, Mahdad, et al. (författare)
  • System and method for data classification and efficient virtual cache coherence without reverse translation
  • 2013
  • Patent (populärvet., debatt m.m.)abstract
    • An on-chip memory hierarchy organization for a multicore processing system is disclosed. The hierarchy supports virtual- addressed private caches and a physical-addressed shared cache. The hierarchy classifies cache line data as private or shared to support a one-directional request response protocol. The classification can be determined from the generational behavior of a cache line in the private caches. Cache lines having a single generation in a private cache are Private, and cache lines having overlapping generations in two or more private caches are Shared. The Private or Shared classification is performed dynamically at run-time in hardware using a single translation lookaside buffer at the interface between the private and shared caches. The coherence protocol uses the data classification in a dynamic write policy for both shared data race free data and private data, differentiating in when data is put back to the shared cache based on the classification.
  •  
Skapa referenser, mejla, bekava och länka
  • Resultat 1-2 av 2

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy