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- Cao, Danni, et al.
(författare)
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Quantification of the impact of traffic incidents on speed reduction: A causal inference based approach
- 2021
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Ingår i: Accident Analysis and Prevention. - : Elsevier BV. - 0001-4575. ; 157
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Tidskriftsartikel (refereegranskat)abstract
- This paper designs a systemic framework to quantify speed reduction induced by traffic incidents using a causal inference framework. The results can provide a reference to traffic managers for evaluating incident severities, thus take proper control measures after the incident in order not to underestimate or overestimate the negative impact. A two-phase scheme is proposed, including impacted region determination and speed reduction quantification. We first propose a Frame Region (FR) method, based on the shockwave propagation, to determine the spatiotemporal impacted region (SIR) using speed map. It is worth-noting that we design a statistical experiment to prove the rationality of congestion threshold selection. Secondly, we introduce a causal inference method for identifying the matched freeway segments. The traffic condition of finally matched freeway segments can be served as non-incident traffic condition of the incident occurred location, which contributes to quantifying the incident impact on speed reduction. We further demonstrate the proposed method in a case study by taking advantage of an incident record and related real freeway speed data in China. An interesting observation is that, along with the freeway segments away from the incident location, the congestion duration time of different freeway segments firstly rises and then decreases. The case study also illustrates the impact of incident on speed lasts almost 3 h and the congestion caused by the incident spreads 11 km, while the average causal effect of incident on all the impacted freeway segments is 42.3 km/h.
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2. |
- Hoencamp, Claire, et al.
(författare)
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3D genomics across the tree of life reveals condensin II as a determinant of architecture type
- 2021
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Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 372:6545, s. 984-989
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Tidskriftsartikel (refereegranskat)abstract
- We investigated genome folding across the eukaryotic tree of life. We find two types of three-dimensional (3D) genome architectures at the chromosome scale. Each type appears and disappears repeatedly during eukaryotic evolution. The type of genome architecture that an organism exhibits correlates with the absence of condensin II subunits. Moreover, condensin II depletion converts the architecture of the human genome to a state resembling that seen in organisms such as fungi or mosquitoes. In this state, centromeres cluster together at nucleoli, and heterochromatin domains merge. We propose a physical model in which lengthwise compaction of chromosomes by condensin II during mitosis determines chromosome-scale genome architecture, with effects that are retained during the subsequent interphase. This mechanism likely has been conserved since the last common ancestor of all eukaryotes.
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