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1.
  • Aad, G, et al. (författare)
  • ATLAS data quality operations and performance for 2015-2018 data-taking
  • 2020
  • Ingår i: Journal of Instrumentation. - : Institute of Physics Publishing (IOPP). - 1748-0221. ; 15:4
  • Tidskriftsartikel (refereegranskat)abstract
    • The ATLAS detector at the Large Hadron Collider reads out particle collision data from over 100 million electronic channels at a rate of approximately 100 kHz, with a recording rate for physics events of approximately 1 kHz. Before being certified for physics analysis at computer centres worldwide, the data must be scrutinised to ensure they are clean from any hardware or software related issues that may compromise their integrity. Prompt identification of these issues permits fast action to investigate, correct and potentially prevent future such problems that could render the data unusable. This is achieved through the monitoring of detector-level quantities and reconstructed collision event characteristics at key stages of the data processing chain. This paper presents the monitoring and assessment procedures in place at ATLAS during 2015-2018 data-taking. Through the continuous improvement of operational procedures, ATLAS achieved a high data quality efficiency, with 95.6% of the recorded proton-proton collision data collected at s=13 TeV certified for physics analysis.
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2.
  • Aad, G, et al. (författare)
  • Combination of searches for Higgs boson pairs in pp collisions at s=13TeV with the ATLAS detector
  • 2020
  • Ingår i: Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 800
  • Tidskriftsartikel (refereegranskat)abstract
    • This letter presents a combination of searches for Higgs boson pair production using up to 36.1 fb−1 of proton–proton collision data at a centre-of-mass energy s=13 TeV recorded with the ATLAS detector at the LHC. The combination is performed using six analyses searching for Higgs boson pairs decaying into the bb¯bb¯, bb¯W+W−, bb¯τ+τ−, W+W−W+W−, bb¯γγ and W+W−γγ final states. Results are presented for non-resonant and resonant Higgs boson pair production modes. No statistically significant excess in data above the Standard Model predictions is found. The combined observed (expected) limit at 95% confidence level on the non-resonant Higgs boson pair production cross-section is 6.9 (10) times the predicted Standard Model cross-section. Limits are also set on the ratio (κλ) of the Higgs boson self-coupling to its Standard Model value. This ratio is constrained at 95% confidence level in observation (expectation) to −5.0
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3.
  • Aad, G, et al. (författare)
  • Combined measurements of Higgs boson production and decay using up to 80 fb-1 of proton-proton collision data at s =13 TeV collected with the ATLAS experiment
  • 2020
  • Ingår i: Physical Review D. - : AMER PHYSICAL SOC. - 1550-2368. ; 101:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Combined measurements of Higgs boson production cross sections and branching fractions are presented. The combination is based on the analyses of the Higgs boson decay modes H→γγ, ZZ∗, WW∗, ττ, bb, μμ, searches for decays into invisible final states, and on measurements of off-shell Higgs boson production. Up to 79.8 fb-1 of proton-proton collision data collected at s=13 TeV with the ATLAS detector are used. Results are presented for the gluon-gluon fusion and vector-boson fusion processes, and for associated production with vector bosons or top-quarks. The global signal strength is determined to be μ=1.11-0.08+0.09. The combined measurement yields an observed (expected) significance for the vector-boson fusion production process of 6.5σ (5.3σ). Measurements in kinematic regions defined within the simplified template cross section framework are also shown. The results are interpreted in terms of modifiers applied to the Standard Model couplings of the Higgs boson to other particles, and are used to set exclusion limits on parameters in two-Higgs-doublet models and in the simplified minimal supersymmetric Standard Model. No significant deviations from Standard Model predictions are observed. © 2020 CERN. © 2020 CERN, for the ATLAS Collaboration. Published by the American Physical Society under the terms of the "https://creativecommons.org/licenses/by/4.0/" Creative Commons Attribution 4.0 International license. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI. Funded by SCOAP3.
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4.
  • Aad, G, et al. (författare)
  • Measurement of Azimuthal Anisotropy of Muons from Charm and Bottom Hadrons in pp Collisions at s =13 TeV with the ATLAS Detector
  • 2020
  • Ingår i: Physical Review Letters. - : AMER PHYSICAL SOC. - 1079-7114 .- 0031-9007. ; 124:8
  • Tidskriftsartikel (refereegranskat)abstract
    • The elliptic flow of muons from the decay of charm and bottom hadrons is measured in pp collisions at √s=13 TeV using a data sample with an integrated luminosity of 150 pb-1 recorded by the ATLAS detector at the LHC. The muons from heavy-flavor decay are separated from light-hadron decay muons using momentum imbalance between the tracking and muon spectrometers. The heavy-flavor decay muons are further separated into those from charm decay and those from bottom decay using the distance-of-closest-approach to the collision vertex. The measurement is performed for muons in the transverse momentum range 4-7 GeV and pseudorapidity range |η| < 2.4. A significant nonzero elliptic anisotropy coefficient v2 is observed for muons from charm decays, while the v2 value for muons from bottom decays is consistent with zero within uncertainties.
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5.
  • Aad, G, et al. (författare)
  • Measurement of isolated-photon plus two-jet production in pp collisions at √s = 13 TeV with the ATLAS detector
  • 2020
  • Ingår i: Journal of High Energy Physics. - : Springer. - 1029-8479 .- 1126-6708. ; 2020:3
  • Tidskriftsartikel (refereegranskat)abstract
    • The dynamics of isolated-photon plus two-jet production in pp collisions at a centre-of-mass energy of 13 TeV are studied with the ATLAS detector at the LHC using a dataset corresponding to an integrated luminosity of 36.1 fb−1. Cross sections are measured as functions of a variety of observables, including angular correlations and invariant masses of the objects in the final state, γ + jet + jet. Measurements are also performed in phase-space regions enriched in each of the two underlying physical mechanisms, namely direct and fragmentation processes. The measurements cover the range of photon (jet) transverse momenta from 150 GeV (100 GeV) to 2 TeV. The tree-level plus parton-shower predictions from Sherpa and Pythia as well as the next-to-leading-order QCD predictions from Sherpa are compared with the measurements. The next-to-leading-order QCD predictions describe the data adequately in shape and normalisation except for regions of phase space such as those with high values of the invariant mass or rapidity separation of the two jets, where the predictions overestimate the data. [Figure not available: see fulltext.] © 2020, The Author(s).
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6.
  • Aad, G, et al. (författare)
  • Measurement of single top-quark production in association with a W boson in the single-lepton channel at √s=8TeV with the ATLAS detector
  • 2021
  • Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 81:8
  • Tidskriftsartikel (refereegranskat)abstract
    • The production cross-section of a top quark in association with a W boson is measured using proton–proton collisions at s√=8TeV. The dataset corresponds to an integrated luminosity of 20.2fb−1, and was collected in 2012 by the ATLAS detector at the Large Hadron Collider at CERN. The analysis is performed in the single-lepton channel. Events are selected by requiring one isolated lepton (electron or muon) and at least three jets. A neural network is trained to separate the tW signal from the dominant tt¯ background. The cross-section is extracted from a binned profile maximum-likelihood fit to a two-dimensional discriminant built from the neural-network output and the invariant mass of the hadronically decaying W boson. The measured cross-section is σtW=26±7pb, in good agreement with the Standard Model expectation.
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7.
  • Aad, G, et al. (författare)
  • Measurement of the CP-violating phase ϕs in Bs0→J/ψϕ decays in ATLAS at 13 TeV
  • 2021
  • Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 81:4
  • Tidskriftsartikel (refereegranskat)abstract
    • A measurement of the Bs0→J/ψϕ decay parameters using 80.5fb-1 of integrated luminosity collected with the ATLAS detector from 13 Te proton–proton collisions at the LHC is presented. The measured parameters include the CP-violating phase ϕs, the width difference Δ Γ s between the Bs0 meson mass eigenstates and the average decay width Γ s. The values measured for the physical parameters are combined with those from 19.2fb-1 of 7 and 8 Te data, leading to the following: ϕs=-0.087±0.036(stat.)±0.021(syst.)radΔΓs=0.0657±0.0043(stat.)±0.0037(syst.)ps-1Γs=0.6703±0.0014(stat.)±0.0018(syst.)ps-1Results for ϕs and Δ Γ s are also presented as 68% confidence level contours in the ϕs–Δ Γ s plane. Furthermore the transversity amplitudes and corresponding strong phases are measured. ϕs and Δ Γ s measurements are in agreement with the Standard Model predictions. © 2021, The Author(s).
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8.
  • Aad, G, et al. (författare)
  • Measurement of the Lund Jet Plane Using Charged Particles in 13 TeV Proton-Proton Collisions with the ATLAS Detector
  • 2020
  • Ingår i: Physical Review Letters. - : American Physical Society (APS). - 1079-7114 .- 0031-9007. ; 124:22
  • Tidskriftsartikel (refereegranskat)abstract
    • The prevalence of hadronic jets at the LHC requires that a deep understanding of jet formation and structure is achieved in order to reach the highest levels of experimental and theoretical precision. There have been many measurements of jet substructure at the LHC and previous colliders, but the targeted observables mix physical effects from various origins. Based on a recent proposal to factorize physical effects, this Letter presents a double-differential cross-section measurement of the Lund jet plane using 139 fb^{-1} of sqrt[s]=13 TeV proton-proton collision data collected with the ATLAS detector using jets with transverse momentum above 675 GeV. The measurement uses charged particles to achieve a fine angular resolution and is corrected for acceptance and detector effects. Several parton shower Monte Carlo models are compared with the data. No single model is found to be in agreement with the measured data across the entire plane.
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9.
  • Aad, G, et al. (författare)
  • Measurement of the transverse momentum distribution of Drell–Yan lepton pairs in proton–proton collisions at √s=13 TeV with the ATLAS detector
  • 2020
  • Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 80:7
  • Tidskriftsartikel (refereegranskat)abstract
    • This paper describes precision measurements of the transverse momentum pTℓℓ (ℓ= e, μ) and of the angular variable ϕη∗ distributions of Drell–Yan lepton pairs in a mass range of 66–116 GeV. The analysis uses data from 36.1 fb- 1 of proton–proton collisions at a centre-of-mass energy of s=13TeV collected by the ATLAS experiment at the LHC in 2015 and 2016. Measurements in electron-pair and muon-pair final states are performed in the same fiducial volumes, corrected for detector effects, and combined. Compared to previous measurements in proton–proton collisions at s=7 and 8TeV, these new measurements probe perturbative QCD at a higher centre-of-mass energy with a different composition of initial states. They reach a precision of 0.2% for the normalized spectra at low values of pTℓℓ. The data are compared with different QCD predictions, where it is found that predictions based on resummation approaches can describe the full spectrum within uncertainties. © 2020, CERN for the benefit of the ATLAS collaboration.
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10.
  • Aad, G, et al. (författare)
  • Measurement of the Z(→ ℓ + ℓ −)γ production cross-section in pp collisions at √s = 13 TeV with the ATLAS detector
  • 2020
  • Ingår i: Journal of High Energy Physics. - : SPRINGER. - 1029-8479 .- 1126-6708. ; 2020:3
  • Tidskriftsartikel (refereegranskat)abstract
    • The production of a prompt photon in association with a Z boson is studied in proton-proton collisions at a centre-of-mass energy s = 13 TeV. The analysis uses a data sample with an integrated luminosity of 139 fb−1 collected by the ATLAS detector at the LHC from 2015 to 2018. The production cross-section for the process pp → ℓ+ℓ−γ + X (ℓ = e, μ) is measured within a fiducial phase-space region defined by kinematic requirements on the photon and the leptons, and by isolation requirements on the photon. An experimental precision of 2.9% is achieved for the fiducial cross-section. Differential cross-sections are measured as a function of each of six kinematic variables characterising the ℓ+ℓ−γ system. The data are compared with theoretical predictions based on next-to-leading-order and next-to-next-to-leading-order perturbative QCD calculations. The impact of next-to-leading-order electroweak corrections is also considered.
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11.
  • Aad, G, et al. (författare)
  • Performance of electron and photon triggers in ATLAS during LHC Run 2
  • 2020
  • Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 80:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Results are presented from the measurement by ATLAS of long-range (| Δ η| > 2) dihadron angular correlations in s=8 and 13 TeV pp collisions containing a Z boson. The analysis is performed using 19.4 fb - 1 of s=8 TeV data recorded during Run 1 of the LHC and 36.1 fb - 1 of s=13 TeV data recorded during Run 2. Two-particle correlation functions are measured as a function of relative azimuthal angle over the relative pseudorapidity range 2 < | Δ η| < 5 for different intervals of charged-particle multiplicity and transverse momentum. The measurements are corrected for the presence of background charged particles generated by collisions that occur during one passage of two colliding proton bunches in the LHC. Contributions to the two-particle correlation functions from hard processes are removed using a template-fitting procedure. Sinusoidal modulation in the correlation functions is observed and quantified by the second Fourier coefficient of the correlation function, v2 , 2, which in turn is used to obtain the single-particle anisotropy coefficient v2. The v2 values in the Z-tagged events, integrated over 0.5 < pT< 5 GeV, are found to be independent of multiplicity and s, and consistent within uncertainties with previous measurements in inclusive pp collisions. As a function of charged-particle pT, the Z-tagged and inclusive v2 values are consistent within uncertainties for pT< 3 GeV. © 2020, CERN for the benefit of the ATLAS collaboration.
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12.
  • Aad, G, et al. (författare)
  • Search for direct production of electroweakinos in final states with missing transverse momentum and a Higgs boson decaying into photons in pp collisions at √s = 13 TeV with the ATLAS detector
  • 2020
  • Ingår i: Journal of High Energy Physics. - : Springer Nature. - 1029-8479 .- 1126-6708. ; 2020:10
  • Tidskriftsartikel (refereegranskat)abstract
    • A search for a chargino-neutralino pair decaying via the 125 GeV Higgs boson into photons is presented. The study is based on the data collected between 2015 and 2018 with the ATLAS detector at the LHC, corresponding to an integrated luminosity of 139 fb−1 of pp collisions at a centre-of-mass energy of 13 TeV. No significant excess over the expected background is observed. Upper limits at 95% confidence level for a massless χ˜10 are set on several electroweakino production cross-sections and the visible cross-section for beyond the Standard Model processes. In the context of simplified supersymmetric models, 95% confidence-level limits of up to 310 GeV in m(χ˜1±/χ˜20), where m(χ˜10) = 0.5 GeV, are set. Limits at 95% confidence level are also set on the χ˜1±χ˜20 cross-section in the mass plane of m(χ˜1±/χ˜20) and m(χ˜10), and on scenarios with gravitino as the lightest supersymmetric particle. Upper limits at the 95% confidence-level are set on the higgsino production cross-section. Higgsino masses below 380 GeV are excluded for the case of the higgsino fully decaying into a Higgs boson and a gravitino. [Figure not available: see fulltext.] © 2020, The Author(s).
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13.
  • Aad, G, et al. (författare)
  • Search for direct production of electroweakinos in final states with one lepton, missing transverse momentum and a Higgs boson decaying into two b-jets in pp collisions at √s=13 TeV with the ATLAS detector
  • 2020
  • Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 80:8
  • Tidskriftsartikel (refereegranskat)abstract
    • The results of a search for electroweakino pair production pp→χ~1±χ~20 in which the chargino (χ~1±) decays into a W boson and the lightest neutralino (χ~10), while the heavier neutralino (χ~20) decays into the Standard Model 125 GeV Higgs boson and a second χ~10 are presented. The signal selection requires a pair of b-tagged jets consistent with those from a Higgs boson decay, and either an electron or a muon from the W boson decay, together with missing transverse momentum from the corresponding neutrino and the stable neutralinos. The analysis is based on data corresponding to 139 fb - 1 of s=13 TeV pp collisions provided by the Large Hadron Collider and recorded by the ATLAS detector. No statistically significant evidence of an excess of events above the Standard Model expectation is found. Limits are set on the direct production of the electroweakinos in simplified models, assuming pure wino cross-sections. Masses of χ~1±/χ~20 up to 740 GeV are excluded at 95% confidence level for a massless χ~10. © 2020, CERN for the benefit of the ATLAS collaboration.
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14.
  • Aad, G, et al. (författare)
  • Search for direct stau production in events with two hadronic τ-leptons in s =13 TeV pp collisions with the ATLAS detector
  • 2020
  • Ingår i: Physical Review D. - : AMER PHYSICAL SOC. - 2470-0010 .- 2470-0029. ; 101:3
  • Tidskriftsartikel (refereegranskat)abstract
    • A search for the direct production of the supersymmetric partners of τ-leptons (staus) in final states with two hadronically decaying τ-leptons is presented. The analysis uses a dataset of pp collisions corresponding to an integrated luminosity of 139 fb-1, recorded with the ATLAS detector at the Large Hadron Collider at a center-of-mass energy of 13 TeV. No significant deviation from the expected Standard Model background is observed. Limits are derived in scenarios of direct production of stau pairs with each stau decaying into the stable lightest neutralino and one τ-lepton in simplified models where the two stau mass eigenstates are degenerate. Stau masses from 120 GeV to 390 GeV are excluded at 95% confidence level for a massless lightest neutralino.
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15.
  • Aad, G, et al. (författare)
  • Search for displaced vertices of oppositely charged leptons from decays of long-lived particles in pp collisions at s=13 TeV with the ATLAS detector
  • 2020
  • Ingår i: Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 801
  • Tidskriftsartikel (refereegranskat)abstract
    • A search for long-lived particles decaying into an oppositely charged lepton pair, μμ, ee, or eμ, is presented using 32.8fb−1 of pp collision data collected at s=13 TeV by the ATLAS detector at the LHC. Candidate leptons are required to form a vertex, within the inner tracking volume of ATLAS, displaced from the primary pp interaction region. No lepton pairs with an invariant mass greater than 12 GeV are observed, consistent with the background expectations derived from data. The detection efficiencies for generic resonances with lifetimes (cτ) of 100–1000 mm decaying into a dilepton pair with masses between 0.1–1.0 TeV are presented as a function of pT and decay radius of the resonances to allow the extraction of upper limits on the cross sections for theoretical models. The result is also interpreted in a supersymmetric model in which the lightest neutralino, produced via squark–antisquark production, decays into ℓ+ℓ′−ν (ℓ,ℓ′=e, μ) with a finite lifetime due to the presence of R-parity violating couplings. Cross-section limits are presented for specific squark and neutralino masses. For a 700 GeV squark, neutralinos with masses of 50–500 GeV and mean proper lifetimes corresponding to cτ values between 1 mm to 6 m are excluded. For a 1.6 TeV squark, cτ values between 3 mm to 1 m are excluded for 1.3 TeV neutralinos. © 2019 The Author(s)
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16.
  • Aad, G, et al. (författare)
  • Search for electroweak production of charginos and sleptons decaying into final states with two leptons and missing transverse momentum in √s=13 TeV pp collisions using the ATLAS detector
  • 2020
  • Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 80:2
  • Tidskriftsartikel (refereegranskat)abstract
    • A search for the electroweak production of charginos and sleptons decaying into final states with two electrons or muons is presented. The analysis is based on 139 fb- 1 of proton–proton collisions recorded by the ATLAS detector at the Large Hadron Collider at s=13 TeV. Three R-parity-conserving scenarios where the lightest neutralino is the lightest supersymmetric particle are considered: the production of chargino pairs with decays via either W bosons or sleptons, and the direct production of slepton pairs. The analysis is optimised for the first of these scenarios, but the results are also interpreted in the others. No significant deviations from the Standard Model expectations are observed and limits at 95% confidence level are set on the masses of relevant supersymmetric particles in each of the scenarios. For a massless lightest neutralino, masses up to 420 Ge are excluded for the production of the lightest-chargino pairs assuming W-boson-mediated decays and up to 1 TeV for slepton-mediated decays, whereas for slepton-pair production masses up to 700 Ge are excluded assuming three generations of mass-degenerate sleptons. © 2020, CERN for the benefit of the ATLAS collaboration.
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17.
  • Aad, G, et al. (författare)
  • Search for flavour-changing neutral currents in processes with one top quark and a photon using 81 fb−1 of pp collisions at s=13TeV with the ATLAS experiment
  • 2020
  • Ingår i: Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 800
  • Tidskriftsartikel (refereegranskat)abstract
    • A search for flavour-changing neutral current (FCNC) events via the coupling of a top quark, a photon, and an up or charm quark is presented using 81 fb−1 of proton–proton collision data taken at a centre-of-mass energy of 13 TeV with the ATLAS detector at the LHC. Events with a photon, an electron or muon, a b-tagged jet, and missing transverse momentum are selected. A neural network based on kinematic variables differentiates between events from signal and background processes. The data are consistent with the background-only hypothesis, and limits are set on the strength of the tqγ coupling in an effective field theory. These are also interpreted as 95% CL upper limits on the cross section for FCNC tγ production via a left-handed (right-handed) tuγ coupling of 36 fb (78 fb) and on the branching ratio for t→γu of 2.8×10−5 (6.1×10−5). In addition, they are interpreted as 95% CL upper limits on the cross section for FCNC tγ production via a left-handed (right-handed) tcγ coupling of 40 fb (33 fb) and on the branching ratio for t→γc of 22×10−5 (18×10−5). © 2019 The Author(s)
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18.
  • Aad, G, et al. (författare)
  • Search for new resonances in mass distributions of jet pairs using 139 fb−1 of pp collisions at √s = 13 TeV with the ATLAS detector
  • 2020
  • Ingår i: Journal of High Energy Physics. - : Springer. - 1029-8479 .- 1126-6708. ; 2020:3
  • Tidskriftsartikel (refereegranskat)abstract
    • A search for new resonances decaying into a pair of jets is reported using the dataset of proton-proton collisions recorded at s = 13 TeV with the ATLAS detector at the Large Hadron Collider between 2015 and 2018, corresponding to an integrated luminosity of 139 fb−1. The distribution of the invariant mass of the two leading jets is examined for local excesses above a data-derived estimate of the Standard Model background. In addition to an inclusive dijet search, events with jets identified as containing b-hadrons are examined specifically. No significant excess of events above the smoothly falling background spectra is observed. The results are used to set cross-section upper limits at 95% confidence level on a range of new physics scenarios. Model-independent limits on Gaussian-shaped signals are also reported. The analysis looking at jets containing b-hadrons benefits from improvements in the jet flavour identification at high transverse momentum, which increases its sensitivity relative to the previous analysis beyond that expected from the higher integrated luminosity. [Figure not available: see fulltext.]
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19.
  • Aad, G, et al. (författare)
  • Search for squarks and gluinos in final states with same-sign leptons and jets using 139 fb −1 of data collected with the ATLAS detector
  • 2020
  • Ingår i: Journal of High Energy Physics. - : Springer Nature. - 1029-8479 .- 1126-6708. ; 2020:6
  • Tidskriftsartikel (refereegranskat)abstract
    • A search for supersymmetric partners of gluons and quarks is presented, involving signatures with jets and either two isolated leptons (electrons or muons) with the same electric charge, or at least three isolated leptons. A data sample of proton-proton collisions at s = 13 TeV recorded with the ATLAS detector at the Large Hadron Collider between 2015 and 2018, corresponding to a total integrated luminosity of 139 fb−1, is used for the search. No significant excess over the Standard Model expectation is observed. The results are interpreted in simplified supersymmetric models featuring both R-parity conservation and R-parity violation, raising the exclusion limits beyond those of previous ATLAS searches to 1600 GeV for gluino masses and 750 GeV for bottom and top squark masses in these scenarios. [Figure not available: see fulltext.] © 2020, The Author(s).
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20.
  • Aad, G, et al. (författare)
  • Search for the HH → bb¯ bb¯ process via vector-boson fusion production using proton-proton collisions at √s = 13 TeV with the ATLAS detector
  • 2020
  • Ingår i: Journal of High Energy Physics. - : Springer Nature. - 1029-8479 .- 1126-6708. ; 2020:7
  • Tidskriftsartikel (refereegranskat)abstract
    • A search for Higgs boson pair production via vector-boson fusion (VBF) in the bb¯ bb¯ final state is carried out with the ATLAS experiment using 126 fb−1 of proton- proton collision data delivered at s = 13 TeV by the Large Hadron Collider. This search is sensitive to VBF production of additional heavy bosons that may decay into Higgs boson pairs, and in a non-resonant topology it can constrain the quartic coupling between the Higgs bosons and vector bosons. No significant excess relative to the Standard Model expectation is observed, and limits on the production cross-section are set at the 95% confidence level for a heavy scalar resonance in the context of an extended Higgs sector, and for non-resonant Higgs boson pair production. Interpretation in terms of the coupling between a Higgs boson pair and two vector bosons is also provided: coupling values normalised to the Standard Model expectation of κ2V< −0.76 and κ2V> 2.90 are excluded at the 95% confidence level in data. [Figure not available: see fulltext.] © 2020, The Author(s).
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21.
  • Aad, G, et al. (författare)
  • Search for the Higgs boson decays H → ee and H → eμ in pp collisions at s=13TeV with the ATLAS detector
  • 2020
  • Ingår i: Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 801
  • Tidskriftsartikel (refereegranskat)abstract
    • Searches for the Higgs boson decays H→ee and H→eμ are performed using data corresponding to an integrated luminosity of 139fb−1 collected with the ATLAS detector in pp collisions at s=13 TeV at the LHC. No significant signals are observed, in agreement with the Standard Model expectation. For a Higgs boson mass of 125 GeV, the observed (expected) upper limit at the 95% confidence level on the branching fraction B(H→ee) is 3.6×10−4 (3.5×10−4) and on B(H→eμ) is 6.2×10−5 (5.9×10−5). These results represent improvements by factors of about five and six on the previous best limits on B(H→ee) and B(H→eμ) respectively. © 2019 The Author
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22.
  • Aad, G, et al. (författare)
  • Searches for lepton-flavour-violating decays of the Higgs boson in s=13 TeV pp collisions with the ATLAS detector
  • 2020
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 800
  • Tidskriftsartikel (refereegranskat)abstract
    • This Letter presents direct searches for lepton flavour violation in Higgs boson decays, H→eτ and H→μτ, performed with the ATLAS detector at the LHC. The searches are based on a data sample of proton–proton collisions at a centre-of-mass energy s=13 TeV, corresponding to an integrated luminosity of 36.1 fb−1. No significant excess is observed above the expected background from Standard Model processes. The observed (median expected) 95% confidence-level upper limits on the lepton-flavour-violating branching ratios are 0.47% (0.34−0.10 +0.13%) and 0.28% (0.37−0.10 +0.14%) for H→eτ and H→μτ, respectively. © 2019 The Author(s)
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23.
  • Arrazuria, Rakel, et al. (författare)
  • Expert workshop summary : Advancing toward a standardized murine model to evaluate treatments for antimicrobial resistance lung infections
  • 2022
  • Ingår i: Frontiers in Microbiology. - : Frontiers Media S.A.. - 1664-302X. ; 13
  • Tidskriftsartikel (refereegranskat)abstract
    • The rise in antimicrobial resistance (AMR), and increase in treatment-refractory AMR infections, generates an urgent need to accelerate the discovery and development of novel anti-infectives. Preclinical animal models play a crucial role in assessing the efficacy of novel drugs, informing human dosing regimens and progressing drug candidates into the clinic. The Innovative Medicines Initiative-funded "Collaboration for prevention and treatment of MDR bacterial infections" (COMBINE) consortium is establishing a validated and globally harmonized preclinical model to increase reproducibility and more reliably translate results from animals to humans. Toward this goal, in April 2021, COMBINE organized the expert workshop "Advancing toward a standardized murine model to evaluate treatments for AMR lung infections". This workshop explored the conduct and interpretation of mouse infection models, with presentations on PK/PD and efficacy studies of small molecule antibiotics, combination treatments (beta -lactam/beta -lactamase inhibitor), bacteriophage therapy, monoclonal antibodies and iron sequestering molecules, with a focus on the major Gram-negative AMR respiratory pathogens Pseudomonas aeruginosa, Klebsiella pneumoniae and Acinetobacter baumannii. Here we summarize the factors of variability that we identified in murine lung infection models used for antimicrobial efficacy testing, as well as the workshop presentations, panel discussions and the survey results for the harmonization of key experimental parameters. The resulting recommendations for standard design parameters are presented in this document and will provide the basis for the development of a harmonized and bench-marked efficacy studies in preclinical murine pneumonia model.
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24.
  • Arrazuria, Rakel, et al. (författare)
  • Variability of murine bacterial pneumonia models used to evaluate antimicrobial agents
  • 2022
  • Ingår i: Frontiers in Microbiology. - : Frontiers Media S.A.. - 1664-302X. ; 13
  • Forskningsöversikt (refereegranskat)abstract
    • Antimicrobial resistance has become one of the greatest threats to human health, and new antibacterial treatments are urgently needed. As a tool to develop novel therapies, animal models are essential to bridge the gap between preclinical and clinical research. However, despite common usage of in vivo models that mimic clinical infection, translational challenges remain high. Standardization of in vivo models is deemed necessary to improve the robustness and reproducibility of preclinical studies and thus translational research. The European Innovative Medicines Initiative (IMI)-funded "Collaboration for prevention and treatment of MDR bacterial infections" (COMBINE) consortium, aims to develop a standardized, quality-controlled murine pneumonia model for preclinical efficacy testing of novel anti-infective candidates and to improve tools for the translation of preclinical data to the clinic. In this review of murine pneumonia model data published in the last 10 years, we present our findings of considerable variability in the protocols employed for testing the efficacy of antimicrobial compounds using this in vivo model. Based on specific inclusion criteria, fifty-three studies focusing on antimicrobial assessment against Pseudomonas aeruginosa, Klebsiella pneumoniae and Acinetobacter baumannii were reviewed in detail. The data revealed marked differences in the experimental design of the murine pneumonia models employed in the literature. Notably, several differences were observed in variables that are expected to impact the obtained results, such as the immune status of the animals, the age, infection route and sample processing, highlighting the necessity of a standardized model.
  •  
25.
  • Bertoli, Gabriele, et al. (författare)
  • Search for light long-lived neutral particles produced in pp collisions at root s=13 TeV and decaying into collimated leptons or light hadrons with the ATLAS detector
  • 2020
  • Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 80:5
  • Tidskriftsartikel (refereegranskat)abstract
    • Several models of physics beyond the Standard Model predict the existence of dark photons, light neutral particles decaying into collimated leptons or light hadrons. This paper presents a search for long-lived dark photons produced from the decay of a Higgs boson or a heavy scalar boson and decaying into displaced collimated Standard Model fermions. The search uses data corresponding to an integrated luminosity of 36.1 fb-1 collected in proton-proton collisions at s=13 Te recorded in 2015-2016 with the ATLAS detector at the Large Hadron Collider. The observed number of events is consistent with the expected background, and limits on the production cross section times branching fraction as a function of the proper decay length of the dark photon are reported. A cross section times branching fraction above 4 pb is excluded for a Higgs boson decaying into two dark photons for dark-photon decay lengths between 1.5 mm and 307 mm.
  •  
26.
  • Brem, Jürgen, et al. (författare)
  • Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors
  • 2022
  • Ingår i: Nature Chemistry. - : Springer Nature. - 1755-4330 .- 1755-4349. ; 14:1, s. 15-24
  • Tidskriftsartikel (refereegranskat)abstract
    • Carbapenems are vital antibiotics, but their efficacy is increasingly compromised by metallo-β-lactamases (MBLs). Here we report the discovery and optimization of potent broad-spectrum MBL inhibitors. A high-throughput screen for NDM-1 inhibitors identified indole-2-carboxylates (InCs) as potential β-lactamase stable β-lactam mimics. Subsequent structure-activity relationship studies revealed InCs as a new class of potent MBL inhibitor, active against all MBL classes of major clinical relevance. Crystallographic studies revealed a binding mode of the InCs to MBLs that, in some regards, mimics that predicted for intact carbapenems, including with respect to maintenance of the Zn(II)-bound hydroxyl, and in other regards mimics binding observed in MBL-carbapenem product complexes. InCs restore carbapenem activity against multiple drug-resistant Gram-negative bacteria and have a low frequency of resistance. InCs also have a good in vivo safety profile, and when combined with meropenem show a strong in vivo efficacy in peritonitis and thigh mouse infection models.
  •  
27.
  • Milstead, David A., et al. (författare)
  • Determination of jet calibration and energy resolution in proton–proton collisions at √s=8TeV using the ATLAS detector
  • 2020
  • Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 80:12
  • Tidskriftsartikel (refereegranskat)abstract
    • The jet energy scale, jet energy resolution, and their systematic uncertainties are measured for jets reconstructed with the ATLAS detector in 2012 using proton–proton data produced at a centre-of-mass energy of 8 TeV with an integrated luminosity of 20fb-1. Jets are reconstructed from clusters of energy depositions in the ATLAS calorimeters using the anti-kt algorithm. A jet calibration scheme is applied in multiple steps, each addressing specific effects including mitigation of contributions from additional proton–proton collisions, loss of energy in dead material, calorimeter non-compensation, angular biases and other global jet effects. The final calibration step uses several in situ techniques and corrects for residual effects not captured by the initial calibration. These analyses measure both the jet energy scale and resolution by exploiting the transverse momentum balance in γ + jet, Z + jet, dijet, and multijet events. A statistical combination of these measurements is performed. In the central detector region, the derived calibration has a precision better than 1% for jets with transverse momentum 150GeV
  •  
28.
  • Milstead, David A., et al. (författare)
  • Measurement of J/ψ production in association with a W ± boson with pp data at 8 TeV
  • 2020
  • Ingår i: Journal of High Energy Physics. - : SPRINGER. - 1029-8479 .- 1126-6708. ; 2020:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Results are presented from the measurement by ATLAS of long-range (| Δ η| > 2) dihadron angular correlations in s=8 and 13 TeV pp collisions containing a Z boson. The analysis is performed using 19.4 fb - 1 of s=8 TeV data recorded during Run 1 of the LHC and 36.1 fb - 1 of s=13 TeV data recorded during Run 2. Two-particle correlation functions are measured as a function of relative azimuthal angle over the relative pseudorapidity range 2 < | Δ η| < 5 for different intervals of charged-particle multiplicity and transverse momentum. The measurements are corrected for the presence of background charged particles generated by collisions that occur during one passage of two colliding proton bunches in the LHC. Contributions to the two-particle correlation functions from hard processes are removed using a template-fitting procedure. Sinusoidal modulation in the correlation functions is observed and quantified by the second Fourier coefficient of the correlation function, v2 , 2, which in turn is used to obtain the single-particle anisotropy coefficient v2. The v2 values in the Z-tagged events, integrated over 0.5 < pT< 5 GeV, are found to be independent of multiplicity and s, and consistent within uncertainties with previous measurements in inclusive pp collisions. As a function of charged-particle pT, the Z-tagged and inclusive v2 values are consistent within uncertainties for pT< 3 GeV. © 2020, CERN for the benefit of the ATLAS collaboration.
  •  
29.
  • Milstead, David A., et al. (författare)
  • Measurement of long-range two-particle azimuthal correlations in Z-boson tagged pp collisions at √s=8 and 13 TeV
  • 2020
  • Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 80:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Results are presented from the measurement by ATLAS of long-range (| Δ η| > 2) dihadron angular correlations in s=8 and 13 TeV pp collisions containing a Z boson. The analysis is performed using 19.4 fb - 1 of s=8 TeV data recorded during Run 1 of the LHC and 36.1 fb - 1 of s=13 TeV data recorded during Run 2. Two-particle correlation functions are measured as a function of relative azimuthal angle over the relative pseudorapidity range 2 < | Δ η| < 5 for different intervals of charged-particle multiplicity and transverse momentum. The measurements are corrected for the presence of background charged particles generated by collisions that occur during one passage of two colliding proton bunches in the LHC. Contributions to the two-particle correlation functions from hard processes are removed using a template-fitting procedure. Sinusoidal modulation in the correlation functions is observed and quantified by the second Fourier coefficient of the correlation function, v2 , 2, which in turn is used to obtain the single-particle anisotropy coefficient v2. The v2 values in the Z-tagged events, integrated over 0.5 < pT< 5 GeV, are found to be independent of multiplicity and s, and consistent within uncertainties with previous measurements in inclusive pp collisions. As a function of charged-particle pT, the Z-tagged and inclusive v2 values are consistent within uncertainties for pT< 3 GeV. © 2020, CERN for the benefit of the ATLAS collaboration.
  •  
30.
  • Milstead, David A., et al. (författare)
  • Measurements of top-quark pair spin correlations in the eμ channel at √s=13 TeV using pp collisions in the ATLAS detector
  • 2020
  • Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 80:8
  • Tidskriftsartikel (refereegranskat)abstract
    • A measurement of observables sensitive to spin correlations in tt¯ production is presented, using 36.1 fb - 1 of pp collision data at s=13 TeV recorded with the ATLAS detector at the Large Hadron Collider. Differential cross-sections are measured in events with exactly one electron and one muon with opposite-sign electric charge as a function of the azimuthal opening angle and the absolute difference in pseudorapidity between the electron and muon candidates in the laboratory frame. The azimuthal opening angle is also measured as a function of the invariant mass of the tt¯ system. The measured differential cross-sections are compared to predictions by several NLO Monte Carlo generators and fixed-order calculations. The observed degree of spin correlation is somewhat higher than predicted by the generators used. The data are consistent with the prediction of one of the fixed-order calculations at NLO, but agree less well with higher-order predictions. Using these leptonic observables, a search is performed for pair production of supersymmetric top squarks decaying into Standard Model top quarks and light neutralinos. Top squark masses between 170 and 230 GeV are largely excluded at the 95% confidence level for kinematically allowed values of the neutralino mass. © 2020, CERN for the benefit of the ATLAS Collaboration.
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