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- Abbafati, Cristiana, et al.
(författare)
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- 2020
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Tidskriftsartikel (refereegranskat)
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- James, SL, et al.
(författare)
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Global injury morbidity and mortality from 1990 to 2017: results from the Global Burden of Disease Study 2017
- 2020
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Ingår i: Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention. - : BMJ. - 1475-5785. ; 26:SUPP_1Supp 1, s. 96-114
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Tidskriftsartikel (refereegranskat)abstract
- Past research in population health trends has shown that injuries form a substantial burden of population health loss. Regular updates to injury burden assessments are critical. We report Global Burden of Disease (GBD) 2017 Study estimates on morbidity and mortality for all injuries.MethodsWe reviewed results for injuries from the GBD 2017 study. GBD 2017 measured injury-specific mortality and years of life lost (YLLs) using the Cause of Death Ensemble model. To measure non-fatal injuries, GBD 2017 modelled injury-specific incidence and converted this to prevalence and years lived with disability (YLDs). YLLs and YLDs were summed to calculate disability-adjusted life years (DALYs).FindingsIn 1990, there were 4 260 493 (4 085 700 to 4 396 138) injury deaths, which increased to 4 484 722 (4 332 010 to 4 585 554) deaths in 2017, while age-standardised mortality decreased from 1079 (1073 to 1086) to 738 (730 to 745) per 100 000. In 1990, there were 354 064 302 (95% uncertainty interval: 338 174 876 to 371 610 802) new cases of injury globally, which increased to 520 710 288 (493 430 247 to 547 988 635) new cases in 2017. During this time, age-standardised incidence decreased non-significantly from 6824 (6534 to 7147) to 6763 (6412 to 7118) per 100 000. Between 1990 and 2017, age-standardised DALYs decreased from 4947 (4655 to 5233) per 100 000 to 3267 (3058 to 3505).InterpretationInjuries are an important cause of health loss globally, though mortality has declined between 1990 and 2017. Future research in injury burden should focus on prevention in high-burden populations, improving data collection and ensuring access to medical care.
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- Beal, Jacob, et al.
(författare)
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Robust estimation of bacterial cell count from optical density
- 2020
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Ingår i: Communications Biology. - : Springer Science and Business Media LLC. - 2399-3642. ; 3:1
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Tidskriftsartikel (refereegranskat)abstract
- Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data.
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- Carpejani, Pablo, et al.
(författare)
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La Investigación-Acción como Instrumento de Perfeccionamiento del Proceso de Materialidad
- 2019
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Ingår i: 7th International Workshop - Advances in Cleaner Production.
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Konferensbidrag (refereegranskat)abstract
- Este estudio tiene como objetivo comprender la implementación de la teoría de la materialidad en la perspectiva de la sostenibilidad corporativa. Ya que el enfoque para conducir la aplicación no es claro, fue necesario realizar una investigación-acción para verificar las principales barreras en la aplicación de la teoría organizada de la Global Reporting Initiative. Para ello, la investigación utilizó el concepto de Sala de Clase Invertida con alumnos de dos clases de sexto período de Ingeniería de Producción. La comprensión e interpretación de estos datos fueron hechas mediante el análisis de contenido en el software ATLAS.ti. Como resultado y principal contribución académica, este estudio precedió a una aplicación real en el ambiente empresarial, así, además de eliminar los posibles problemas de desarrollo en el abordaje, el artículo tendrá la función de ser el eslabón intermediario entre la teoría y la práctica en la aplicación de la materialidad en entornos empresariales. La limitación del artículo se expone en el muestreo, pero esta poca experiencia práctica de los alumnos con el tema también puede ser presenciada en las organizaciones por medios de sus colaboradores que, a menudo, pueden desconocer el enfoque de la teoría. El aspecto de originalidad es presentado por ser, hasta entonces, la primera investigación que simula una aplicación de materialidad.
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- Marques, Marcia, et al.
(författare)
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Water environments : Anthropogenic pressures and ecosystem changes in the Atlantic drainage basins of Brazil
- 2004
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Ingår i: Ambio. - : Royal Swedish Academy of Sciences. - 0044-7447 .- 1654-7209. ; 33:1-2, s. 68-77
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Tidskriftsartikel (refereegranskat)abstract
- Densely occupied drainage basins and coastal zones in developing countries that are facing economic growth are likely to suffer from moderate to severe environmental impacts regarding different issues. The catchment basins draining towards the Atlantic coast from northeastern to southern Brazil include a wide range of climatic zones and diverse ecosystems. Within its borders lies the Atlantic rain forest, significant extensions of semiarid thorn forests (caatinga), vast tree and scrub woodlands (cerrado) and most of the 6670 km of the Brazilian coast and its marine ecosystems. In recent decades, human activities have increasingly advanced over these natural resources. Littoralization has imposed a burden on coastal habitats and communities. Most of the native vegetation of the cerrado and caatinga was removed and only 7% of the original Atlantic rainforest still exists. Estuaries, bays and coastal lagoons have been irreversibly damaged. Land uses, damming and water diversion have become the major driving forces for habitat loss and aquatic ecosystem modification. Regardless of the contrast between the drought-affected northeastern Brazil and the much more prosperous and industrialized southeastern/southern Brazil, the impacts on habitat and communities were found equally severe in both cases. Attempts to halt environmental degradation have not been effective. Instead of focusing on natural resources separately, it is suggested that more integrated environmental policies that focus on aquatic ecosystems integrity are introduced.
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