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Pharmacotherapy of ...
Pharmacotherapy of Pulmonary Hypertension / edited by Marc Humbert, Oleg V. Evgenov, Johannes-Peter Stasch.
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Humbert, Marc. (redaktör/utgivare)
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Evgenov, Oleg V. (redaktör/utgivare)
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Stasch, Johannes-Peter. (redaktör/utgivare)
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- ISBN 9783642386640
- Berlin, Heidelberg : Springer Berlin Heidelberg : 2013
- Engelska IX, 576 p. 66 illus., 56 illus. in color.
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Serie: Handbook of Experimental Pharmacology, 0171-2004 ; 218
- Relaterad länk:
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http://dx.doi.org/10... (Table of Contents / Abstracts) (856other)
Innehållsförteckning
Ämnesord
Stäng
- Preface.- Part I. Pulmonary hypertension: conceptual bases of the disease. Pulmonary hypertension: definition, classification, and epidemiology. Pulmonary hypertension: pathophysiology and signalling pathways. Pulmonary hypertension: pathology. Pulmonary hypertension: biomarkers. Pulmonary hypertension: animal models -- Part II. Pulmonary hypertension: established therapies. General supportive care. Calcium channel blockers. Prostacyclins. Endothelin receptor antagonists. Phosphodiesterase 5 inhibitors -- Part III. Pulmonary hypertension: novel pathways and emerging therapies Soluble guanylate cyclase stimulators. Therapeutics targeting dysregulated redox equilibrium and endothelial dysfunction (NOXs, sGC activators, GSNOR). Rho-kinase inhibitors. Serotonin transporters and serotonin receptors. PDGF inhibitors. Novel anti-proliferative strategies beyond imatinib. Immunosuppressive agents. Vasoactive peptides. Inhibitors of cGMP/cAMP metabolism (MRP4, MRP5, PDE1). Old targets re-visited. Stem cells and cell based therapy -- Part IV. Conclusions and Outlook. Pulmonary hypertension: evidence-based management in the modern era and future directions.
Ämnesord
- Medicine. (LCSH)
- Medical laboratories. (LCSH)
- Toxicology. (LCSH)
- Pharmaceutical technology. (LCSH)
- Internal medicine. (LCSH)
- Pneumology. (LCSH)
- Biomedicine.
- Pharmacology/Toxicology.
- Pharmaceutical Sciences/Technology.
- Internal Medicine.
- Pneumology/Respiratory System.
- Laboratory Medicine.
- Molecular Medicine.
Publikations- och innehållstyp
- RM1-950 (LCC)
- MED071000 (ämneskategori)
- 615 (DDC)
- V (kssb/8 (machine generated))
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