Sökning: onr:"22067877" > Whole Grain Rye Int...
Fältnamn | Indikatorer | Metadata |
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000 | 04141naa a22006133a 4500 | |
001 | 22067877 | |
003 | SE-LIBR | |
005 | 20171206153021.0 | |
007 | cr|||||||||||| | |
008 | 171206s2014 sw |||| o |||| ||eng c | |
024 | 7 | a http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2379152 uri |
024 | 7 | a urn:nbn:se:uu:diva-2379152 urn |
024 | 7 | a 10.1371/journal.pone.01108272 doi |
040 | a S | |
041 | 0 | a eng |
042 | 9 EPLK | |
100 | 1 | a Magnusdottir, Ola Kally4 aut |
245 | 1 0 | a Whole Grain Rye Intake, Reflected by a Biomarker, Is Associated with Favorable Blood Lipid Outcomes in Subjects with the Metabolic Syndromeh [Elektronisk resurs]b A Randomized Study |
260 | c 2014 | |
500 | a Published | |
506 | 0 | a gratis |
520 | a Background and Aim: Few studies have explored the possible plasma cholesterol lowering effects of rye consumption. The aim of this secondary analysis in the SYSDIET study was to investigate the association between plasma alkylresorcinols (AR), a biomarker for whole grain wheat and rye intake, and blood lipid concentrations in a population with metabolic syndrome. Furthermore, we analyzed the associations between the AR C17:0/C21:0 ratio, a suggested marker of the relative intake of whole grain/bran rye, and blood lipid concentrations. Methods: Participants were 30-65 years of age, with body mass index (BMI) 27-40 kg/m(2) and had metabolic syndrome. Individuals were recruited through six centers in the Nordic countries and randomized either to a healthy Nordic diet (ND, n = 93), rich in whole grain rye and wheat, as well as berries, fruits and vegetables, rapeseed oil, three fish meals per week and low-fat dairy products, or a control diet (n = 65) for 18/24 weeks. Associations between total plasma AR concentration and C17:0/C21:0 homologue ratio and blood lipids were investigated in pooled (ND + control group) regression analyses at 18/24 weeks adjusted for baseline value for the dependent variable, age, BMI and statin use. Results: When adjusted for confounders, total plasma AR at 18/24 weeks was not significantly associated with blood lipids but the AR ratio C17:0/C21:0 was inversely associated with LDL cholesterol concentrations (B (95% Cl): -0.41 (-0.80 to -0.02)), log LDL/HDL cholesterol ratio (-0.20 (-0.37 to -0.03)), log non-HDL cholesterol (-0.20 (-0.37 to -0.03)), log apolipoprotein B (-0.12 (-0.24 to 0.00)) and log triglyceride concentrations (-0.35 (-0.59 to -0.12)). Discussion: Increased proportion of whole grain rye, reflected by a biomarker, in the diet is associated with favorable blood lipid outcomes, a relationship that should be further investigated. | |
650 | 7 | a Medical and Health Sciences2 hsv |
650 | 7 | a Health Sciences2 hsv |
650 | 7 | a Nutrition and Dietetics2 hsv |
650 | 7 | a Medicin och hälsovetenskap2 hsv |
650 | 7 | a Hälsovetenskaper2 hsv |
650 | 7 | a Näringslära2 hsv |
700 | 1 | a Landberg, Rikard4 aut |
700 | 1 | a Gunnarsdottir, Ingibjorg4 aut |
700 | 1 | a Cloetens, Lieselotte4 aut |
700 | 1 | a Akesson, Bjorn4 aut |
700 | 1 | a Rosqvist, Fredrik4 aut |
700 | 1 | a Schwab, Ursula4 aut |
700 | 1 | a Herzig, Karl-Heinz4 aut |
700 | 1 | a Hukkanen, Janne4 aut |
700 | 1 | a Savolainen, Markku J.4 aut |
700 | 1 | a Brader, Lea4 aut |
700 | 1 | a Hermansen, Kjeld4 aut |
700 | 1 | a Kolehmainen, Marjukka4 aut |
700 | 1 | a Poutanen, Kaisa4 aut |
700 | 1 | a Uusitupa, Matti4 aut |
700 | 1 | a Riserus, Ulf4 aut |
700 | 1 | a Thorsdottir, Inga4 aut |
710 | 1 2 | a Uppsala universitetb Medicinska och farmaceutiska vetenskapsområdet4 pbl |
772 | 1 8 | i channel recordw 19753896 |
773 | 0 8 | i Värdpublikationt PLoS ONEg 9:10, e110827x 1932-6203 |
856 | 4 0 | u http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-237915 |
856 | 4 0 | u http://dx.doi.org/10.1371/journal.pone.0110827 |
856 | 4 0 | u http://uu.diva-portal.org/smash/get/diva2:770601/FULLTEXT01 |
841 | 5 APISa x ab 171206||0000|||||001||||||000000e 1 | |
024 | 7 | 5 APISa urn:nbn:se:uu:diva-2379152 urn |
852 | 5 APISb APIS | |
856 | 4 0 | 5 APISu http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-237915 |
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