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Systemic inflammato...
Systemic inflammatory impact of periodontitis on acute coronary syndrome
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- Widen, Cecilia (författare)
- Kristianstad Univ, Sch Hlth & Soc, SE-29188 Kristianstad, Sweden.
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- Holmer, Helene (författare)
- Kristianstad Cent Hosp, Kristianstad, Sweden.,Kristianstad Hospital,Centralsjukhuset Kristianstad
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- Coleman, Michael (författare)
- Aston Univ, Birmingham, W Midlands, England.,England
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- Tudor, Marian (författare)
- Kristianstad Cent Hosp, Kristianstad, Sweden.,Kristianstad Hospital,Centralsjukhuset Kristianstad
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- Ohlsson, Ola (författare)
- Kristianstad Univ, Sch Hlth & Soc, SE-29188 Kristianstad, Sweden.;Kristianstad Cent Hosp, Kristianstad, Sweden.,Oral Health - Public Health - Quality of Life (OHAL),Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL)
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- Sattlin, Susanna (författare)
- Kristianstad Univ, Sch Hlth & Soc, SE-29188 Kristianstad, Sweden.,Oral Health - Public Health - Quality of Life (OHAL),Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL)
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- Renvert, Stefan (författare)
- Kristianstad University,Blekinge Tekniska Högskola,Institutionen för hälsa
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- Persson, Gösta Rutger (författare)
- Kristianstad Univ, Sch Hlth & Soc, SE-29188 Kristianstad, Sweden.;Univ Washington, Seattle, WA 98195 USA.,Oral Health - Public Health - Quality of Life (OHAL),Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL)
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Kristianstad Univ, Sch Hlth & Soc, SE-29188 Kristianstad, Sweden Kristianstad Cent Hosp, Kristianstad, Sweden. (creator_code:org_t)
- 2016-07-02
- 2016
- Engelska.
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Ingår i: Journal of Clinical Periodontology. - : Wiley. - 0303-6979 .- 1600-051X. ; 43:9, s. 713-719
- Relaterad länk:
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https://publications...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- AimA causative relationship between acute coronary syndrome (ACS) and periodontitis has yet to be defined. The aim of this study was to assess differences in levels of serum cytokines between individuals with or without ACS or periodontal comorbidity. Material and MethodsIn a case-control study, individuals with ACS (78 individuals, 10.3% females) and matching healthy controls (78 individuals, 28.2% females) were included. Medical and dental examinations were performed to diagnose ACS and periodontitis. Serum levels of cytokines were assessed, using Luminex technology. ResultsA diagnosis of periodontitis in the ACS and control group was diagnosed in 52.6% and 12.8% of the individuals, respectively. The unadjusted odds-ratio that individuals with ACS also had periodontitis was 7.5 (95% CI: 3.4, 16.8, p<0.001). Independent of periodontal conditions, individuals with ACS had significantly higher serum levels of IL8 (mean: 44.3 and 40.0pg/ml) and vascular endothelial growth factor (VEGF) (mean: 82.3 and 55.3pg/ml) than control individuals. A diagnosis of periodontitis made no difference in serum cytokine expressions. ConclusionElevated serum levels of VEGF were associated with ACS. Serum cytokine expression in individuals with ACS is unrelated to periodontal conditions.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
Nyckelord
- cardiovascular disease
- cytokines
- hs-CRP
- human
- oral disease
- serum
- VEGF
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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