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The clinical signif...
The clinical significance of 10-m walk test standardizations in Parkinson's disease
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- Lindholm, Beata (författare)
- Lund University
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- Nilsson, Maria H (författare)
- Lund University
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- Hansson, Oskar (författare)
- Lund University
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- Hagell, Peter (författare)
- Högskolan Kristianstad,Forskningsmiljön PRO-CARE, Patient Reported Outcomes - Clinical Assessment Research and Education,Forskningsplattformen för Hälsa i samverkan,Avdelningen för sjuksköterskeutbildningarna och integrerad hälsovetenskap
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(creator_code:org_t)
- 2018
- 2018
- Engelska.
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Ingår i: Journal of Neurology. - 0340-5354 .- 1432-1459. ; 265:8, s. 1829-1835
- Relaterad länk:
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http://hkr.diva-port... (primary) (Raw object)
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https://link.springe...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- BACKGROUND: The 10-m walk test (10MWT) is a widely used measure of gait speed in Parkinson's disease (PD). However, it is unclear if different standardizations of its conduct impact test results.AIM OF THE STUDY: We examined the clinical significance of two aspects of the standardization of the 10MWT in mild PD: static vs. dynamic start, and a single vs. repeated trials. Implications for fall prediction were also explored.METHODS: 151 people with PD (mean age and PD duration, 68 and 4 years, respectively) completed the 10MWT in comfortable gait speed with static and dynamic start (two trials each), and gait speed (m/s) was recorded. Participants then registered all prospective falls for 6 months.RESULTS: Absolute mean differences between outcomes from the various test conditions ranged between 0.016 and 0.040 m/s (effect sizes, 0.06-0.14) with high levels of agreement (intra-class correlation coefficients, 0.932-0.987) and small standard errors of measurement (0.032-0.076 m/s). Receiver operating characteristic curves showed similar discriminate abilities for prediction of future falls across conditions (areas under curves, 0.70-0.73). Cut-off points were estimated at 1.1-1.2 m/s.CONCLUSIONS: Different 10MWT standardizations yield very similar results, suggesting that there is no practical need for an acceleration distance or repeated trials when conducting this test in mild PD.
Ämnesord
- MEDICAL AND HEALTH SCIENCES -- Other Medical Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Annan medicin och hälsovetenskap (hsv//swe)
Nyckelord
- Falls
- Parkinson disease
- Prediction
- Test standardization
- The 10-m walk test
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)