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Pressure and flow properties of cannulae for extracorporeal membrane oxygenation I : return (arterial) cannulae

Broman, Lars Mikael (författare)
Karolinska Institutet
Prahl Wittberg, Lisa, Docent, 1978- (författare)
KTH,Linné Flow Center, FLOW,BioMEx
Westlund, C. Jerker (författare)
Karolinska Univ Hosp, ECMO Ctr Karolinska, Dept Pediat Perioperat Med & Intens Care, Eugeniavagen 23, S-17176 Stockholm, Sweden.
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Gilbers, Martijn (författare)
Maastricht Univ, Dept Cardiothorac Surg, Heart & Vasc Ctr, Cardiovasc Res Inst Maastricht CARIM,Med Hosp, Maastricht, Netherlands.;Maastricht Univ, Dept Physiol, Maastricht, Netherlands.
da Camara, Luisa Perry (författare)
Hosp Curry Cabral, Ctr Hosp Lisboa Cent, Lisbon, Portugal.
Swol, Justyna (författare)
EuroElso, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;Paracelsus Med Univ, Dept Pulmonol, Intens Care Med, Nurnberg, Germany.
Taccone, Fabio S. (författare)
EuroElso, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;ULB, Dept Intens Care, Hop Erasme, Brussels, Belgium.
Malfertheiner, Maximilian V. (författare)
EuroElso, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;Univ Med Ctr Regensburg, Dept Internal Med Cardiol & Pneumol 2, Regensburg, Germany.
Di Nardo, Matteo (författare)
EuroElso, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;Childrens Hosp Bambino Gesu, IRCCS, Pediat Intens Care Unit, Rome, Italy.
Vercaemst, Leen (författare)
EuroElso, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;Univ Hosp Gasthuisberg, Dept Perfus, Leuven, Belgium.
Barrett, Nicholas A. (författare)
EuroElso, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;Guys & St Thomas NHS Fdn Trust, Dept Crit Care, London, England.;Guys & St Thomas NHS Fdn Trust, Severe Resp Failure Serv, London, England.
Pappalardo, Federico (författare)
EuroElso, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;Univ Vita Salute San Raffaele, Adv Heart Failure & Mech Circulatory Support Prog, Hosp San Raffaele, Milan, Italy.
Belohlavek, Jan (författare)
EuroElso, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;Charles Univ Prague, Gen Univ Hosp Prague, Dept Cardiovasc Med, Dept Med 2, Prague, Czech Republic.;Charles Univ Prague, Fac Med 1, Prague, Czech Republic.
Mueller, Thomas (författare)
EuroElso, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;Univ Med Ctr Regensburg, Dept Internal Med Cardiol & Pneumol 2, Regensburg, Germany.
Belliato, Mirko (författare)
EuroElso, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;Fdn IRCCS Policlin San Matteo, UOC Anestesia & Rianimaz 1, Pavia, Italy.
Lorusso, Roberto (författare)
EuroElso, Working Grp Innovat & Technol, Newcastle Upon Tyne, Tyne & Wear, England.;Maastricht Univ, Dept Cardiothorac Surg, Heart & Vasc Ctr, Cardiovasc Res Inst Maastricht CARIM,Med Hosp, Maastricht, Netherlands.
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 (creator_code:org_t)
2019-04-10
2019
Engelska.
Ingår i: Perfusion. - : SAGE PUBLICATIONS LTD. - 0267-6591 .- 1477-111X. ; 34, s. 58-64
Relaterad länk:
http://repositorio.c...
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https://urn.kb.se/re...
https://doi.org/10.1...
http://kipublication...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Adequate extracorporeal membrane oxygenation support in the adult requires cannulae permitting blood flows up to 6-8 L/minute. In accordance with Poiseuille's law, flow is proportional to the fourth power of cannula inner diameter and inversely proportional to its length. Poiseuille's law can be applied to obtain the pressure drop of an incompressible, Newtonian fluid (such as water) flowing in a cylindrical tube. However, as blood is a pseudoplastic non-Newtonian fluid, the validity of Poiseuille's law is questionable for prediction of cannula properties in clinical practice. Pressure-flow charts with non-Newtonian fluids, such as blood, are typically not provided by the manufacturers. A standardized laboratory test of return (arterial) cannulae for extracorporeal membrane oxygenation was performed. The aim was to determine pressure-flow data with human whole blood in addition to manufacturers' water tests to facilitate an appropriate choice of cannula for the desired flow range. In total, 14 cannulae from three manufacturers were tested. Data concerning design, characteristics, and performance were graphically presented for each tested cannula. Measured blood flows were in most cases 3-21% lower than those provided by manufacturers. This was most pronounced in the narrow cannulae (15-17 Fr) where the reduction ranged from 27% to 40% at low flows and 5-15% in the upper flow range. These differences were less apparent with increasing cannula diameter. There was a marked disparity between manufacturers. Based on the measured results, testing of cannulae including whole blood flows in a standardized bench test would be recommended.

Ämnesord

TEKNIK OCH TEKNOLOGIER  -- Maskinteknik -- Strömningsmekanik och akustik (hsv//swe)
ENGINEERING AND TECHNOLOGY  -- Mechanical Engineering -- Fluid Mechanics and Acoustics (hsv//eng)

Nyckelord

arterial
return
extracorporeal membrane oxygenation
cannula
pressure flow
blood
water
extracorporeal life support

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