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A genome-wide trans...
A genome-wide transcriptomic analysis of protein-coding genes in human blood cells
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- Uhlén, Mathias (author)
- KTH,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden;Karolinska Inst, Dept Neurosci, Stockholm, Sweden;Tech Univ Denmark, Novo Nordisk Fdn Ctr Biosustainabil, Lyngby, Denmark
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- Karlsson, Max (author)
- KTH,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden
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- Zhong, Wen (author)
- KTH,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden
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- Abdellah, Tebani (author)
- KTH,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden
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- Pou, Christian (author)
- Karolinska Inst, Dept Womens & Childrens Hlth, Sci Life Lab, Stockholm, Sweden.
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- Mikes, Jaromir (author)
- Karolinska Institutet,Karolinska Inst, Dept Womens & Childrens Hlth, Sci Life Lab, Stockholm, Sweden
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- Lakshmikanth, Tadepally (author)
- Karolinska Institutet,Karolinska Inst, Dept Womens & Childrens Hlth, Sci Life Lab, Stockholm, Sweden
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- Forsström, Björn (author)
- KTH,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden
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- Edfors, Fredrik (author)
- KTH,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden
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- Odeberg, Jacob, Professor, 1963- (author)
- Karolinska Institutet,KTH,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden;Karolinska Univ Hosp, Coagulat Unit, Dept Hematol, Stockholm, Sweden
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- Mardinoglu, Adil (author)
- KTH,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden;Kings Coll London, Ctr Host Microbiome Interact, Fac Dent Oral & Craniofacial Sci, London, England
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- Zhang, Cheng (author)
- KTH,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden
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- von Feilitzen, Kalle (author)
- KTH,Systembiologi,KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden
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- Mulder, Jan (author)
- Karolinska Institutet,Karolinska Inst, Dept Neurosci, Stockholm, Sweden
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- Sjostedt, Evelina (author)
- Karolinska Inst, Dept Neurosci, Stockholm, Sweden.
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- Hober, Andreas (author)
- KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden
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- Oksvold, Per (author)
- KTH,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden
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- Zwahlen, Martin (author)
- KTH,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden
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- Pontén, Fredrik (author)
- Uppsala universitet,Klinisk och experimentell patologi,Uppsala Univ, Dept Immunol Genet & Pathol, Rudbeck Lab, Uppsala, Sweden.,Uppsala universitet, Klinisk och experimentell patologi, Sweden
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- Lindskog, Cecilia (author)
- Uppsala universitet,Klinisk och experimentell patologi,Uppsala Univ, Dept Immunol Genet & Pathol, Rudbeck Lab, Uppsala, Sweden.,Uppsala universitet, Klinisk och experimentell patologi, Sweden
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- Sivertsson, Åsa (author)
- KTH,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden
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- Fagerberg, Linn (author)
- KTH,Science for Life Laboratory, SciLifeLab,KTH Royal Inst Technol, Sci Life Lab, Stockholm, Sweden
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- Brodin, Petter (author)
- Karolinska Institutet,Karolinska Inst, Dept Womens & Childrens Hlth, Sci Life Lab, Stockholm, Sweden;Karolinska Univ Hosp, Unit Pediat Rheumatol, Stockholm, Sweden
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(creator_code:org_t)
- American Association for the Advancement of Science, 2019
- 2019
- English.
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In: Science. - : American Association for the Advancement of Science. - 0036-8075 .- 1095-9203. ; 366:6472, s. 1471-
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Blood is the predominant source for molecular analyses in humans, both in clinical and research settings. It is the target for many therapeutic strategies, emphasizing the need for comprehensive molecular maps of the cells constituting human blood. In this study, we performed a genome-wide transcriptomic analysis of protein-coding genes in sorted blood immune cell populations to characterize the expression levels of each individual gene across the blood cell types. All data are presented in an interactive, open-access Blood Atlas as part of the Human Protein Atlas and are integrated with expression profiles across all major tissues to provide spatial classification of all protein-coding genes. This allows for a genome-wide exploration of the expression profiles across human immune cell populations and all major human tissues and organs.
Subject headings
- NATURVETENSKAP -- Biologi -- Genetik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Genetics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Medicinsk bioteknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Medical Biotechnology (hsv//eng)
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- ref (subject category)
- art (subject category)
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Science
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- By the author/editor
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Uhlén, Mathias
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Karlsson, Max
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Zhong, Wen
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Abdellah, Tebani
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Pou, Christian
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Mikes, Jaromir
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show more...
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Lakshmikanth, Ta ...
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Forsström, Björn
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Edfors, Fredrik
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Odeberg, Jacob, ...
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Mardinoglu, Adil
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Zhang, Cheng
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von Feilitzen, K ...
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Mulder, Jan
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Sjostedt, Evelin ...
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Hober, Andreas
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Oksvold, Per
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Zwahlen, Martin
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Pontén, Fredrik
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Lindskog, Cecili ...
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Sivertsson, Åsa
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Fagerberg, Linn
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Brodin, Petter
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- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Genetics
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Medical Biotechn ...
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and Medical Biotechn ...
- Articles in the publication
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Science
- By the university
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Royal Institute of Technology
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Uppsala University
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Karolinska Institutet
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Linköping University