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Routine omics colle...
Routine omics collection is a golden opportunity for European human research in space and analog environments
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- Cope, Henry (author)
- Univ Nottingham, Sch Med, Derby DE22 3DT, England.
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- Willis, Craig R. G. (author)
- Ohio Univ, Heritage Coll Osteopath Med, Dept Biomed Sci, Athens, OH 45701 USA.;Ohio Univ, Ohio Musculoskeletal & Neurol Inst, Athens, OH 45701 USA.;Univ Bradford, Fac Life Sci, Sch Chem & Biosci, Bradford BD7 1DP, W Yorkshire, England.
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- MacKay, Matthew J. (author)
- Weill Cornell Med, Dept Physiol & Biophys, New York, NY USA.
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- Rutter, Lindsay A. (author)
- Univ Tsukuba, Fac Med, Transborder Med Res Ctr, Tsukuba, Ibaraki 3058575, Japan.;Univ Tsukuba, Fac Med, Dept Genome Biol, Tsukuba, Ibaraki 3058575, Japan.
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- Toh, Li Shean (author)
- Univ Nottingham, Sch Pharm, Nottingham NG7 2RD, England.
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- Williams, Philip M. (author)
- Univ Nottingham, Sch Pharm, Nottingham NG7 2RD, England.
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- Herranz, Raul (author)
- Ctr Invest Biol Margarita Salas CSIC, Madrid 28040, Spain.
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- Borg, Joseph (author)
- Univ Malta, Fac Hlth Sci, Dept Appl Biomed Sci, Msida Msd 2080, Malta.
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- Bezdan, Daniela (author)
- Univ Tubingen, Inst Med Genet & Appl Genom, Tubingen, Germany.;Univ Tubingen, NGS Competence Ctr Tubingen NCCT, Tubingen, Germany.;yuri GmbH, Meckenbeuren, Germany.
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- Giacomello, Stefania (author)
- KTH,Science for Life Laboratory, SciLifeLab
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- Muratani, Masafumi (author)
- Univ Tsukuba, Fac Med, Transborder Med Res Ctr, Tsukuba, Ibaraki 3058575, Japan.;Univ Tsukuba, Fac Med, Dept Genome Biol, Tsukuba, Ibaraki 3058575, Japan.
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- Mason, Christopher E. (author)
- Weill Cornell Med, Dept Physiol & Biophys, New York, NY USA.;Weill Cornell Med, HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsau, New York, NY USA.;Weill Cornell Med, WorldQuant Initiat Quantitat Predict, New York, NY USA.;Weill Cornell Med, Feil Family Brain & Mind Res Inst, New York, NY USA.
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- Etheridge, Timothy (author)
- Univ Exeter, Coll Life & Environm Sci, Dept Sport & Hlth Sci, Exeter EX1 2LU, Devon, England.
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- Szewczyk, Nathaniel J. (author)
- Univ Nottingham, Sch Med, Derby DE22 3DT, England.;Ohio Univ, Heritage Coll Osteopath Med, Dept Biomed Sci, Athens, OH 45701 USA.;Ohio Univ, Ohio Musculoskeletal & Neurol Inst, Athens, OH 45701 USA.
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Univ Nottingham, Sch Med, Derby DE22 3DT, England Ohio Univ, Heritage Coll Osteopath Med, Dept Biomed Sci, Athens, OH 45701 USA.;Ohio Univ, Ohio Musculoskeletal & Neurol Inst, Athens, OH 45701 USA.;Univ Bradford, Fac Life Sci, Sch Chem & Biosci, Bradford BD7 1DP, W Yorkshire, England. (creator_code:org_t)
- Elsevier BV, 2022
- 2022
- English.
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In: PATTERNS. - : Elsevier BV. - 2666-3899. ; 3:10, s. 100550-
- Related links:
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https://doi.org/10.1...
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Abstract
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- Widespread generation and analysis of omics data have revolutionized molecular medicine on Earth, yet its power to yield new mechanistic insights and improve occupational health during spaceflight is still to be fully realized in humans. Nevertheless, rapid technological advancements and ever-regular spaceflight programs mean that longitudinal, standardized, and cost-effective collection of human space omics data are firmly within reach. Here, we consider the practicality and scientific return of different sampling methods and omic types in the context of human spaceflight, We also appraise ethical and legal considerations pertinent to omics data derived from European astronauts and spaceflight participants (SFPs). Ultimately, we propose that a routine omics collection program in spaceflight and analog environments presents a golden opportunity. Unlocking this bright future of artificial intelligence (AI)-driven analyses and personalized medicine approaches will require further investigation into best practices, including policy design and standardization of omics data, metadata, and sampling methods.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology (hsv//eng)
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- ref (subject category)
- art (subject category)
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- By the author/editor
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Cope, Henry
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Willis, Craig R. ...
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MacKay, Matthew ...
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Rutter, Lindsay ...
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Toh, Li Shean
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Williams, Philip ...
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show more...
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Herranz, Raul
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Borg, Joseph
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Bezdan, Daniela
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Giacomello, Stef ...
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Muratani, Masafu ...
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Mason, Christoph ...
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Etheridge, Timot ...
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Szewczyk, Nathan ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Medical Biotechn ...
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PATTERNS
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Royal Institute of Technology