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Sökning: onr:"swepub:oai:DiVA.org:liu-140034" > Antiarrhythmic medi...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004510naa a2200481 4500
001oai:DiVA.org:liu-140034
003SwePub
008170829s2017 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1400342 URI
0247 a https://doi.org/10.1016/j.ijcard.2017.05.0282 DOI
040 a (SwePub)liu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Alhede, Christinau Herlev Gentofte University Hospital, Denmark4 aut
2451 0a Antiarrhythmic medication is superior to catheter ablation in suppressing supraventricular ectopic complexes in patients with atrial fibrillation
264 1b ELSEVIER IRELAND LTD,c 2017
338 a print2 rdacarrier
500 a Funding Agencies|Hans and Nora Buchards Foundation; Aage and Gerda Henschs Foundation; Jens Anker Andersens Foundation
520 a Background: Supraventricular ectopic complexes (SVEC) originating in the pulmonary veins are known triggers of atrial fibrillation (AF) which led to the development of pulmonary vein isolation for AF. However, the long-term prevalence of SVEC after catheter ablation (CA) as compared to antiarrhythmic medication (AAD) is unknown. Our aims were to compare the prevalence of SVEC after AAD and CA and to estimate the association between baseline SVEC burden and AF burden during 24 months of follow-up. Methods: Patients with paroxysmal AF (N = 260) enrolled in the MANTRA PAF trial were treated with AAD (N = 132) or CA (N = 128). At baseline and 3, 6, 12, 18 and 24 months follow-up patients underwent 7-day Holter monitoring to assess SVEC and AF burden. We compared SVEC burden between treatments with Wilcoxon sum rank test. Results: Patients treated with AAD had significantly lower daily SVEC burden during follow-up as compared to CA (AAD: 19 [6-58] versus CA: 39 [14-125], p = 0.003). SVEC burden increased post-procedurally followed by a decrease after CA whereas after AAD SVEC burden decreased and stabilized after 3 months of follow-up. Patients with low SVEC burden had low AF burden after both treatments albeit this was more pronounced after CA at 24 months of follow-up. Conclusion: AAD was superior to CA in suppressing SVEC burden after treatment of paroxysmal AF. After CA SVEC burden increased immediately post-procedural followed by a decrease whereas after AAD an early decrease was observed. Lower SVEC burden was highly associated with lower AF burden during follow-up especially after CA. (C) 2017 Elsevier B.V. All rights reserved.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng
653 a Arrhythmia; Treatment; Ablation; Premature ectopic beats; Recurrence
7001 a Lauridsen, Trine K.u Herlev Gentofte University Hospital, Denmark4 aut
7001 a Johannessen, Arneu Herlev Gentofte University Hospital, Denmark4 aut
7001 a Dixen, Ulriku Hvidovre University Hospital, Denmark4 aut
7001 a Jensen, Jan S.u Herlev Gentofte University Hospital, Denmark4 aut
7001 a Raatikainen, Pekkau Helsinki University Hospital, Finland4 aut
7001 a Hindricks, Gerhardu Leipzig University Hospital, Germany4 aut
7001 a Walfridsson, Håkanu Linköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US4 aut0 (Swepub:liu)hakwa83
7001 a Kongstad, Oleu Lund University Hospital, Sweden4 aut
7001 a Pehrson, Steenu Rigshosp, Denmark4 aut
7001 a Englund, Andersu Örebro University Hospital, Sweden4 aut
7001 a Hartikainen, Juhau Kupio University Hospital, Finland4 aut
7001 a Hansen, Peter S.u Varde Heart Centre, Denmark4 aut
7001 a Nielsen, Jens C.u Aarhus University Hospital, Denmark4 aut
7001 a Jons, Christianu Rigshosp, Denmark4 aut
7102 a Herlev Gentofte University Hospital, Denmarkb Hvidovre University Hospital, Denmark4 org
7730 t International Journal of Cardiologyd : ELSEVIER IRELAND LTDg 244, s. 186-191q 244<186-191x 0167-5273x 1874-1754
8564 u https://helda.helsinki.fi/bitstream/10138/297901/1/Antiarrhythmic_medication_is_superior.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-140034
8564 8u https://doi.org/10.1016/j.ijcard.2017.05.028

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