onr:"swepub:oai:DiVA.org:liu-141934"
Sökning: onr:"swepub:oai:DiVA.org:liu-141934" > beta-Configured cli...
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04023naa a2200469 4500 | |
| 001 | oai:DiVA.org:liu-141934 | |
| 003 | SwePub | |
| 008 | 171013s2017 | |||||||||||000 ||eng| | |
| 009 | oai:DiVA.org:uu-336822 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1419342 URI |
| 024 | 7 | a https://doi.org/10.1039/c7nj00716g2 DOI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3368222 URI |
| 040 | a (SwePub)liud (SwePub)uu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Elgland, Mathias,d 1987-u Linköpings universitet,Kemi,Tekniska fakulteten,Linkopings Univ, IFM Dept Biol Chem & Phys, S-58183 Linkoping, Sweden.4 aut0 (Swepub:liu)matel79 |
| 245 | 1 0 | a beta-Configured clickable [F-18] FDGs as novel F-18-fluoroglycosylation tools for PET |
| 264 | c 2017 | |
| 264 | 1 | b ROYAL SOC CHEMISTRY,c 2017 |
| 338 | a electronic2 rdacarrier | |
| 500 | a Funding Agencies|Swedish Foundation for Strategic Research; Swedish Research Council | |
| 520 | a In oncology and neurology the F-18-radiolabeled glucose analogue 2-deoxy-2-[F-18]fluoro-D-glucose ([F-18]FDG) is by far the most commonly employed metabolic imaging agent for positron emission tomography (PET). Herein, we report a novel synthetic route to beta-configured mannopyranoside precursors and a chemoselective F-18-fluoroglycosylation method that employ two b-configured [F-18]FDG derivatives equipped with either a terminal azide or alkyne aglycon respectively, for use as a CuAAC clickable tool set for PET. The b-configured precursors provided the corresponding [F-18]FDGs in a radiochemical yield of 77-88%. Further, the clickability of these [F-18]FDGs was investigated by click coupling to the suitably functionalized Fmoc-protected amino acids, Fmoc-N-(propargyl)-glycine and Fmoc-3-azido-L-alanine, which provided the F-18-fluoroglycosylated amino acid conjugates in radiochemical yields of 75-83%. The F-18-fluoroglycosylated amino acids presented herein constitute a new and interesting class of metabolic PET radiotracers. | |
| 650 | 7 | a NATURVETENSKAPx Kemix Organisk kemi0 (SwePub)104052 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Chemical Sciencesx Organic Chemistry0 (SwePub)104052 hsv//eng |
| 650 | 7 | a NATURVETENSKAPx Kemi0 (SwePub)1042 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Chemical Sciences0 (SwePub)1042 hsv//eng |
| 700 | 1 | a Nordeman, Patriku Uppsala universitet,Avdelningen för organisk farmaceutisk kemi,Uppsala University, Sweden4 aut0 (Swepub:uu)patno435 |
| 700 | 1 | a Fyrner, Timmy,d 1981-u Linköpings universitet,Kemi,Tekniska fakulteten,Linkopings Univ, IFM Dept Biol Chem & Phys, S-58183 Linkoping, Sweden.4 aut0 (Swepub:liu)timfy80 |
| 700 | 1 | a Antoni, Gunnaru Uppsala universitet,Avdelningen för Molekylär Avbildning,Uppsala University, Sweden4 aut0 (Swepub:uu)gunnarat |
| 700 | 1 | a Nilsson, Peter,d 1970-u Linköpings universitet,Kemi,Tekniska fakulteten,Linkopings Univ, IFM Dept Biol Chem & Phys, S-58183 Linkoping, Sweden.4 aut0 (Swepub:liu)petni61 |
| 700 | 1 | a Konradsson, Peter,d 1957-u Linköpings universitet,Kemi,Tekniska fakulteten,Linkopings Univ, IFM Dept Biol Chem & Phys, S-58183 Linkoping, Sweden.4 aut0 (Swepub:liu)petko14 |
| 710 | 2 | a Linköpings universitetb Kemi4 org |
| 773 | 0 | t New Journal of Chemistryd : ROYAL SOC CHEMISTRYg 41:18, s. 10231-10236q 41:18<10231-10236x 1144-0546x 1369-9261 |
| 856 | 4 | u https://liu.diva-portal.org/smash/get/diva2:1149178/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 | u http://liu.diva-portal.org/smash/get/diva2:1149178/FULLTEXT01 |
| 856 | 4 | u https://doi.org/10.1039/c7nj00716gy Fulltext |
| 856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1168204/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-141934 |
| 856 | 4 8 | u https://doi.org/10.1039/c7nj00716g |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-336822 |
Hitta via bibliotek
- New Journal of Chemistry (Sök värdpublikationen i LIBRIS)
Till lärosätets databas
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
Hitta mer i SwePub
- Av författaren/redakt...
- Elgland, Mathias ...
- Nordeman, Patrik
- Fyrner, Timmy, 1 ...
- Antoni, Gunnar
- Nilsson, Peter, ...
- Konradsson, Pete ...
- Om ämnet
-
- NATURVETENSKAP
- NATURVETENSKAP
- och Kemi
- och Organisk kemi
-
- NATURVETENSKAP
- NATURVETENSKAP
- och Kemi
- Artiklar i publikationen
- New Journal of C ...
- Av lärosätet
- Linköpings universitet
- Uppsala universitet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
