Sökning: onr:"swepub:oai:DiVA.org:liu-60888" >
Treatment of acute ...
-
Butler, Christopher CCardiff University
(författare)
Treatment of acute cough/lower respiratory tract infection by antibiotic class and associated outcomes: a 13 European country observational study in primary care
- Artikel/kapitelEngelska2010
Förlag, utgivningsår, omfång ...
-
2010-09-18
-
Oxford University Press,2010
-
printrdacarrier
Nummerbeteckningar
-
LIBRIS-ID:oai:DiVA.org:liu-60888
-
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-60888URI
-
https://doi.org/10.1093/jac/dkq336DOI
Kompletterande språkuppgifter
-
Språk:engelska
-
Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
-
Ämneskategori:ref swepub-contenttype
-
Ämneskategori:art swepub-publicationtype
Anmärkningar
-
Acute cough/lower respiratory tract infection (LRTI) is one of the commonest reasons for consulting and antibiotic prescribing. There are theoretical reasons why treatment with particular antibiotic classes may aid recovery more than others, but empirical, pragmatic evidence is lacking. We investigated whether treatment with a particular antibiotic class (amoxicillin) was more strongly associated with symptom score resolution and time to patients reporting recovery than each of eight other antibiotic classes or no antibiotic treatment for acute cough/LRTI. Clinicians recorded history, examination findings, symptom severity and antibiotic treatment for 3402 patients in a 13 country prospective observational study of adults presenting in 14 primary care research networks with acute cough/LRTI. 2714 patients completed a symptom score daily for up to 28 days and recorded the day on which they felt recovered. A three-level autoregressive moving average model (1,1) model investigated logged daily symptom scores to analyse symptom resolution. A two-level survival model analysed time to reported recovery. Clinical presentation was controlled for using clinician-recorded symptoms, sputum colour, temperature, age, co-morbidities, smoking status and duration of illness prior to consultation. Compared with amoxicillin, no antibiotic class (and no antibiotic treatment) was associated with clinically relevant improved symptom resolution (all coefficients in the range -0.02 to 0.01 and all P values greater than 0.12). No antibiotic class (and no antibiotic treatment) was associated with faster time to recovery than amoxicillin. Treatment by antibiotic class was not associated with symptom resolution or time to recovery in adults presenting to primary care with acute cough/LRTI.
Ämnesord och genrebeteckningar
-
antibiotic resistance
-
patient outcome
-
clinical epidemiology
-
antibiotic choice
-
MEDICINE
-
MEDICIN
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Kelly, Mark JCardiff University
(författare)
-
Goossens, HermanUniversity of Antwerp
(författare)
-
Verheij, TheoUniversity Medical Centre Utrecht
(författare)
-
Little, PaulUniversity of Southampton
(författare)
-
Melbye, HasseUniversity of Tromso
(författare)
-
Torres, AntoniUniversity of Barcelona
(författare)
-
Mölstad, SigvardLinköpings universitet,Allmänmedicin,Hälsouniversitetet(Swepub:liu)sigmo13
(författare)
-
Godycki-Cwirko, MaciekMedical University Lodz
(författare)
-
Almirall, JordiHospital Mataro
(författare)
-
Blasi, FrancescoUniversity of Milan
(författare)
-
Schaberg, TomDeaconess Hospital Rotenburg
(författare)
-
Edwards, PeterEly Bridge Surg, Cardiff
(författare)
-
Rautakorpi, Ulla-MaijaTampere Off
(författare)
-
Hupkova, HelenaComenius University
(författare)
-
Wood, JosephCardiff University
(författare)
-
Nuttall, JacquiCardiff University
(författare)
-
Coenen, SamuelUniversity of Antwerp
(författare)
-
Cardiff UniversityUniversity of Antwerp
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY: Oxford University Press65:11, s. 2472-24780305-74531460-2091
Internetlänk
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Butler, Christop ...
-
Kelly, Mark J
-
Goossens, Herman
-
Verheij, Theo
-
Little, Paul
-
Melbye, Hasse
-
visa fler...
-
Torres, Antoni
-
Mölstad, Sigvard
-
Godycki-Cwirko, ...
-
Almirall, Jordi
-
Blasi, Francesco
-
Schaberg, Tom
-
Edwards, Peter
-
Rautakorpi, Ulla ...
-
Hupkova, Helena
-
Wood, Joseph
-
Nuttall, Jacqui
-
Coenen, Samuel
-
visa färre...
- Artiklar i publikationen
-
JOURNAL OF ANTIM ...
- Av lärosätet
-
Linköpings universitet