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Antibodies Against ...
Antibodies Against Gonadotropin-Releasing Hormone in Patients with Posterior Laryngitis
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- Pendleton, Hillevi (författare)
- Lund University,Lunds universitet,Laryngoesofagologi, allergi och livskvalitet,Forskargrupper vid Lunds universitet,Laryngoesophagology, Allergy and Life Quality,Lund University Research Groups
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- Alm, Ragnar (författare)
- Lund University,Lunds universitet,Kardiovaskulär forskning - immunitet och ateroskleros,Forskargrupper vid Lunds universitet,Cardiovascular Research - Immunity and Atherosclerosis,Lund University Research Groups
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- Nordin Fredrikson, Gunilla (författare)
- Lund University,Lunds universitet,Malmö högskola,Institutionen för biomedicinsk vetenskap (BMV),Kardiovaskulär forskning - immunitet och ateroskleros,Forskargrupper vid Lunds universitet,Cardiovascular Research - Immunity and Atherosclerosis,Lund University Research Groups
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- Ohlsson, Bodil (författare)
- Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups
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(creator_code:org_t)
- Libertas Academica, 2013
- 2013
- Engelska.
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Ingår i: Drug Target Insights. - : Libertas Academica. - 1177-3928. ; :7, s. 1-8
- Relaterad länk:
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https://mau.diva-por... (primary) (Raw object)
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https://portal.resea... (primary) (free)
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http://www.ncbi.nlm....
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.4...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- Patients with functional gastrointestinal disorders express antibodies against gonadotropin-releasing hormone (GnRH) in serum. One common cause of posterior laryngitis (PL) is extra-esophageal reflux, but a functional etiology has also been suggested. The aim of this study was to scrutinize patients with PL with regard to the presence of GnRH antibodies and to examine the association between antibodies and symptoms and reflux. Consecutive PL patients were included after examination. Serum was analyzed for the presence of antibodies using an enzyme-linked immunosorbent assay (ELISA) method and expressed as relative units (RU). Two age- and gender-matched healthy subjects per case served as controls. The prevalence of IgM GnRH antibodies in patients was 35% compared with 28% in controls (P = 0.06), with higher levels in patients (0.8 (0.3-2.2) RU) than in controls (0.2 (0.1-0.6) RU) (P = 0.007). The corresponding IgG antibody prevalences were 43% and 4%, respectively (P = 0.001), with no difference in levels (P = 0.70). There was no association between antibodies and clinical findings
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmakologi och toxikologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmacology and Toxicology (hsv//eng)
Nyckelord
- gonadotropin-releasing hormone
- posterior laryngitis
- functional disorders
- acid reflux
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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