onr:"swepub:oai:DiVA.org:oru-69420"
Sökning: onr:"swepub:oai:DiVA.org:oru-69420" > Does zero atrial fi...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04966naa a2200409 4500 | |
| 001 | oai:DiVA.org:oru-69420 | |
| 003 | SwePub | |
| 008 | 181008s2017 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-694202 URI |
| 024 | 7 | a https://doi.org/10.1093/ehjci/eux157.0012 DOI |
| 040 | a (SwePub)oru | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Björkenheim, Anna,d 1980-u Department of Cardiology, Örebro University Hospital, Örebro, Sweden4 aut0 (Swepub:oru)anbm |
| 245 | 1 0 | a Does zero atrial fibrillation burden after atrial fibrillation ablation mean that patients are free of symptoms? |
| 264 | c 2017-06-20 | |
| 264 | 1 | b Oxford University Press,c 2017 |
| 338 | a print2 rdacarrier | |
| 500 | a | |
| 520 | a Introduction: Success of atrial fibrillation (AF) ablation is usually defined as freedom of AF, although symptomatic relief often is what the patient’s desire. After ablation the proportion of ‘silent’ AF increases and success based on symptomatic AF recurrence may be overestimated.Purpose: To investigate the symptomatology of patients who are truly free of AF after ablation.Methods: In 57 patients the symptomatology after AF ablation was assessed as perceived by the patient using a validated AF-specific symptom questionnaire (AF6) and the overall treatment effect (OTE), and as classified by the physician using the EHRA score, at baseline, 6, 12 and 24 months. The cardiac rhythm was continuously monitored by an implantable loop recorder throughout the 2-year follow-up.Results: At 6, 12 and 24 months 14 (26%), 23 (43%) and 23 (43%) patients had an AF burden 0% during the past 6 months, and 13 of them had an AF burden 0% during the entire 2 year follow-up. All patients reported ‘OTE better’ at all time-points. All patients were also classified into EHRA I at 6 months. Being completely free of AF for six months periods did not mean complete freedom of symptoms, but the median AF6 sum score was consistently low with a narrowing IQR over time, 0 (IQR 0-27), 0.5 (IQR 0-7) and 0 (IQR 0-11) at 6, 12 and 24 months. At 6 months 8/14 patients (57%) scored AF6=0, the others 6, 11, 26, 28, 30 and 46 points. At 12 months 13/23 patients (56%) scored AF6=0, the others 1,1,3,3,5,7,7,7,14 and 22 points. At 24 months 12/23 (52%) patients scored AF6=0, the others 1, 1, 2, 4, 9, 11, 17, 20, 24, 32 and 42 points. Among the AF6 items, ‘worry/anxiety due to AF’ was the most common, while ‘tiredness due to AF’ was the highest scoring item. In the patients with AF burden 0% during the entire 2-year follow-up all patients were improved in OTE and all patients were classified into EHRA class I at all times after ablation and the median AF6 sum score was 4 (IQR0-28), 0.5 (IQR 0-8) and 1 (0-5) at 6, 12 and 24 months after ablation.Conclusions: Sudden elimination of AF by ablation does not automatically eliminate all symptoms that the patients associated with AF, but all patients felt better and were classified in EHRA class I at all time-points. Less than a half of the patients at any time-point scored some symptoms, but the symptoms gradually decreased over time, especially between 6 and 12 months. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Kardiologi0 (SwePub)302062 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cardiac and Cardiovascular Systems0 (SwePub)302062 hsv//eng |
| 700 | 1 | a Brandes, A.u Department of Cardiology, Odense University Hospital, Odense, Denmark4 aut |
| 700 | 1 | a Magnuson, A.u Örebro University Hospital, Clinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro, Sweden4 aut |
| 700 | 1 | a Chemnitz, A.u Department of Cardiology, Odense University Hospital, Odense, Denmark4 aut |
| 700 | 1 | a Svedberg, L.u Department of Cardiology, Örebro University Hospital, Örebro, Sweden4 aut |
| 700 | 1 | a Edvardsson, N.u Sahlgrenska Academy at Sahlgrenska University Hospital, Göteborg, Sweden4 aut |
| 700 | 1 | a Poçi, Dritan,d 1969-u Department of Cardiology, Örebro University Hospital, Örebro, Sweden4 aut0 (Swepub:oru)dnpi |
| 710 | 2 | a Department of Cardiology, Örebro University Hospital, Örebro, Swedenb Department of Cardiology, Odense University Hospital, Odense, Denmark4 org |
| 773 | 0 | t Europace, Supplementsd : Oxford University Pressg 19:Duppl. 3, s. iii264-iii264q 19:Duppl. 3<iii264-iii264x 1099-6044x 1749-365X |
| 773 | 0 | t EP Europaced : Oxford University Pressg 19:Duppl. 3, s. iii264-iii264q 19:Duppl. 3<iii264-iii264x 1099-5129x 1532-2092 |
| 856 | 4 | u https://doi.org/10.1093/ehjci/eux157.001y Fulltext |
| 856 | 4 | u https://academic.oup.com/europace/article-pdf/19/suppl_3/iii264/17903406/eux157.001.pdf |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-69420 |
| 856 | 4 8 | u https://doi.org/10.1093/ehjci/eux157.001 |
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