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Data-driven questio...
Data-driven questionnaire-based cluster analysis of asthma in Swedish adults
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- Kisiel, Marta, 1984- (author)
- Uppsala universitet,Arbets- och miljömedicin
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- Zhou, Xingwu (author)
- Uppsala universitet,Lung- allergi- och sömnforskning,Klinisk fysiologi,Karolinska Inst, Dept Publ Hlth Sci, Stockholm, Sweden.
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- Sundh, Josefin, 1972- (author)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Respiratory Medicine,Orebro Univ, Fac Med & Hlth, Dept Resp Med, Orebro, Sweden.
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- Ställberg, Björn, Docent (author)
- Uppsala universitet,Allmänmedicin och preventivmedicin
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- Lisspers, Karin, Docent, 1954- (author)
- Uppsala universitet,Allmänmedicin och preventivmedicin
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- Malinovschi, Andrei, 1978- (author)
- Uppsala universitet,Klinisk fysiologi
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- Sandelowsky, Hanna (author)
- Karolinska Institutet
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- Montgomery, Scott, 1961- (author)
- Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Clinical Epidemiology Division, Department of Medicine, Karolinska Institute, Stockholm, Sweden; Department of Epidemiology and Public Health, University College London, London, UK,Orebro Univ, Sch Med Sci, Clin Epidemiol & Biostat, Orebro, Sweden.;Karolinska Inst, Dept Med, Clin Epidemiol Div, Stockholm, Sweden.;UCL, Dept Epidemiol & Publ Hlth, London, England.
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- Nager, Anna (author)
- Karolinska Institutet
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- Janson, Christer (author)
- Uppsala universitet,Lung- allergi- och sömnforskning
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(creator_code:org_t)
- 2020-04-06
- 2020
- English.
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In: npj Primary Care Respiratory Medicine. - : Nature Research. - 2055-1010. ; 30:1
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Abstract
Subject headings
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- The aim of this study was to identify asthma phenotypes through cluster analysis. Cluster analysis was performed using self-reported characteristics from a cohort of 1291 Swedish asthma patients. Disease burden was measured using the Asthma Control Test (ACT), the mini Asthma Quality of Life Questionnaire (mini-AQLQ), exacerbation frequency and asthma severity. Validation was performed in 748 individuals from the same geographical region. Three clusters; early onset predominantly female, adult onset predominantly female and adult onset predominantly male, were identified. Early onset predominantly female asthma had a higher burden of disease, the highest exacerbation frequency and use of inhaled corticosteroids. Adult onset predominantly male asthma had the highest mean score of ACT and mini-AQLQ, the lowest exacerbation frequency and higher proportion of subjects with mild asthma. These clusters, based on information from clinical questionnaire data, might be useful in primary care settings where the access to spirometry and biomarkers is limited.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Kisiel, Marta, 1 ...
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Zhou, Xingwu
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Sundh, Josefin, ...
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Ställberg, Björn ...
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Lisspers, Karin, ...
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Malinovschi, And ...
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Sandelowsky, Han ...
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Montgomery, Scot ...
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Nager, Anna
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Janson, Christer
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Respiratory Medi ...
- Articles in the publication
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npj Primary Care ...
- By the university
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Örebro University
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Uppsala University
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Karolinska Institutet