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Renography with a s...
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Bäck, Anna-Karin,1971-Örebro universitet,Institutionen för hälsovetenskaper,Department of Radiology,Örebro Univ, Fac Hlth Sci, Dept Radiol, Örebro, Sweden.
(författare)
Renography with a semiautomated algorithm for diuretic decision 7 min postradiopharmaceutical administration : a feasibility study
- Artikel/kapitelEngelska2020
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Lippincott Williams & Wilkins,2020
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LIBRIS-ID:oai:DiVA.org:oru-85883
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https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-85883URI
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https://doi.org/10.1097/MNM.0000000000001261DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-423233URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:144767134URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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Funding Agency:Research committee of Örebro County Council, Sweden
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OBJECTIVE: The F+10 method for diuretic renography (diuretics given 10 min after the radiopharmaceutical) could be a time-conserving method. This method involves a 30-min dynamic acquisition where diuretics are administered only when necessary by the Nuclear Medicine technologist performing the examination. The purpose of this study was to assess the method's performance and to discover the optimal threshold of residual activity for a diuretic administration 7 min into the F+10 renography by reprocessing raw data from prior performed examinations with 20-min acquisitions without diuretics.METHODS: Retrospectively, raw data from 320 original examinations of adult patients performed from 2013 to 2015 were reprocessed into 7-min series and categorized as requiring diuretic or not. The diuretic decisions made by an expert panel were used as a reference. A receiver-operating characteristic curve was drawn to assess the optimal cutoff value for the residual renal activity. Sensitivity, specificity, positive and negative predictive values, as well as the Youden J index were calculated.RESULT: The experts classified 50% (160 examinations) as in need of diuretics. The receiver-operating characteristic curve demonstrated the theoretical optimal cutoff value at 7 min to be 94% of maximum activity (sensitivity 0.93, specificity 0.81, Youden J index 0.73). A clinically acceptable threshold is suggested to be 85% (sensitivity 0.99, specificity 0.59, Youden J index 0.58).CONCLUSION: Tc-mercaptoacetyltriglycine renography with the F+10 method and the threshold 85% for diuretic decision 7 min into the renography is a feasible and acceptable method in clinical practice.
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Savvopoulos, ChristosDepartment of Radiology, Faculty of Medicine and Health, Örebro University, Örebro,Örebro Univ, Fac Med & Hlth, Dept Radiol, Örebro, Sweden.
(författare)
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Kero, TanjaUppsala universitet,Radiologi(Swepub:uu)tanke311
(författare)
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Grybäck, PerKarolinska Institutet
(författare)
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Geijer, Håkan,1961-Örebro universitet,Institutionen för medicinska vetenskaper,Örebro Univ, Fac Med & Hlth, Dept Radiol, Örebro, Sweden.(Swepub:oru)hngr
(författare)
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Örebro universitetInstitutionen för hälsovetenskaper
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Nuclear medicine communications: Lippincott Williams & Wilkins41:10, s. 1018-10250143-36361473-5628
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