Search: onr:"swepub:oai:DiVA.org:oru-99599" >
Development of gut ...
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Wernroth, LisaUppsala universitet,Uppsala kliniska forskningscentrum (UCR),Molekylär epidemiologi,Science for Life Laboratory, SciLifeLab
(author)
Development of gut microbiota during the first 2 years of life
- Article/chapterEnglish2022
Publisher, publication year, extent ...
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2022-05-31
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Nature Portfolio,2022
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:oru-99599
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https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-99599URI
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https://doi.org/10.1038/s41598-022-13009-3DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-470208URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:149767281URI
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https://res.slu.se/id/publ/117569URI
Supplementary language notes
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Language:English
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Summary in:English
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Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Funding agency:Swedish National Infrastructure for Computing (SNIC) at Uppsala Multidisciplinary Center for Advanced Computational Science (UPPMAX) sens2018616
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Although development of microbiota in childhood has been linked to chronic immune-related conditions, early childhood determinants of microbiota development have not been fully elucidated. We used 16S rRNA sequencing to analyse faecal and saliva samples from 83 children at four time-points during their first 2 years of life and from their mothers. Our findings confirm that gut microbiota in infants have low diversity and highlight that some properties are shared with the oral microbiota, although inter-individual differences are present. A considerable convergence in gut microbiota composition was noted across the first 2 years of life, towards a more diverse adult-like microbiota. Mode of delivery accounted for some of the inter-individual variation in early childhood, but with a pronounced attenuation over time. Our study extends previous research with further characterization of the major shift in gut microbiota composition during the first 2 years of life.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Peura, SariSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Uppsala universitet,Science for Life Laboratory, SciLifeLab,Molekylär epidemiologi,Limnologi,Department of Forest Mycology and Plant Pathology, Swedish University of Agricultural Science, Uppsala, Sweden;Swedish Nuclear Fuel and Waste Management Co., (SKB), Stockholm, Sweden,Uppsala University,Swedish Nuclear Fuel and Waste Management Company (SKB)
(author)
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Hedman, Anna M.Karolinska Institutet
(author)
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Hetty, Susanne,PhD,1979-Uppsala universitet,Klinisk diabetologi och metabolism(Swepub:uu)sustr921
(author)
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Vicenzi, SilviaUppsala universitet,Molekylär epidemiologi,Science for Life Laboratory, SciLifeLab,School of Medicine, University of Tasmania, Hobart, Australia;Division of Biological Sciences, University of California, San Diego, USA
(author)
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Kennedy, Beatrice,1982-Uppsala universitet,Molekylär epidemiologi,Science for Life Laboratory, SciLifeLab(Swepub:uu)beake215
(author)
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Fall, Katja,1971-Örebro universitet,Institutionen för medicinska vetenskaper,Clinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro, Sweden;Integrative Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden(Swepub:oru)kafl
(author)
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Svennblad, BodilUppsala universitet,Medicinsk epidemiologi(Swepub:uu)bosve677
(author)
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Andolf, EllikaKarolinska Institutet
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Pershagen, GoranKarolinska Institutet
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Theorell-Haglöw, JennyUppsala universitet,Lung- allergi- och sömnforskning,Molekylär epidemiologi,Science for Life Laboratory, SciLifeLab(Swepub:uu)jethe020
(author)
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Nguyen, Diem,PhDUppsala universitet,Science for Life Laboratory, SciLifeLab,Molekylär epidemiologi,Uppsala University(Swepub:slu)48385
(author)
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Sayols-Baixeras, SergiUppsala universitet,Molekylär epidemiologi,Science for Life Laboratory, SciLifeLab(Swepub:uu)sersa467
(author)
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Dekkers, KoenUppsala universitet,Molekylär epidemiologi,Science for Life Laboratory, SciLifeLab(Swepub:uu)koede543
(author)
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Bertilsson, StefanSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för vatten och miljö,Department of Aquatic Sciences and Assessment(Swepub:uu)stber839
(author)
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Almqvist, CatarinaKarolinska Institutet
(author)
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Dicksved, JohanSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för husdjurens utfodring och vård (HUV),Department of Animal Nutrition and Management(Swepub:slu)47518
(author)
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Fall, Tove,1979-Uppsala universitet,Science for Life Laboratory, SciLifeLab,Molekylär epidemiologi(Swepub:uu)tovfa878
(author)
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Uppsala universitetUppsala kliniska forskningscentrum (UCR)
(creator_code:org_t)
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Sveriges lantbruksuniversitet
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In:Scientific Reports: Nature Portfolio12:12045-2322
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Wernroth, Lisa
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Peura, Sari
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Hedman, Anna M.
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Hetty, Susanne, ...
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Vicenzi, Silvia
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Kennedy, Beatric ...
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Fall, Katja, 197 ...
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Svennblad, Bodil
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Andolf, Ellika
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Pershagen, Goran
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Sayols-Baixeras, ...
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Örebro University
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