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The size of the anterior corpus callosum correlates with the strength of hemispheric encoding-retrieval asymmetry in the ventrolateral prefrontal cortex

Kompus, Kristiina (author)
Umeå universitet,Diagnostisk radiologi,Fysiologi,Umeå centrum för funktionell hjärnavbildning (UFBI),University of Bergen
Kalpouzos, Gregoria (author)
Umeå universitet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Fysiologi,Stockholm University
Westerhausen, Rene (author)
University of Bergen
 (creator_code:org_t)
Amsterdam : Elsevier BV, 2011
2011
English.
In: Brain Research. - Amsterdam : Elsevier BV. - 0006-8993 .- 1872-6240. ; 1419, s. 61-67
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Functional lateralization of episodic memory processes in the frontal lobe is an area of intense study in the field of cognitive neuroimaging. Yet, to date there is insufficient knowledge of what role the interhemispheric structural connectivity plays in this lateralized organization. We analyzed functional and structural magnetic resonance imaging data from healthy adult volunteers who performed an associative encoding and retrieval task. We examined the relationship between functional voxel-based relative asymmetry of encoding and retrieval in the frontal lobes and the size of the anterior corpus callosum (antCC; corrected for brain size). The size of the antCC was strongly associated to the relative encoding-retrieval asymmetry in the ventrolateral prefrontal cortex (BA 47). These findings show that the functional asymmetry of episodic memory processes in the frontal lobes is associated with the structural connectivity between the hemispheres.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Neurosciences (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Neurologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Neurology (hsv//eng)

Keyword

Corpus callosum
Functional lateralization
Episodic memory
HERA model

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Brain Research
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Umeå University
Karolinska Institutet

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