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Physical Activity a...
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Bonn, Stephanie E.Karolinska Institutet
(författare)
Physical Activity and Survival among Men Diagnosed with Prostate Cancer
- Artikel/kapitelEngelska2015
Förlag, utgivningsår, omfång ...
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AMER ASSOC CANCER RESEARCH,2015
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LIBRIS-ID:oai:DiVA.org:umu-100146
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-100146URI
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https://doi.org/10.1158/1055-9965.EPI-14-0707DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-40677URI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-365948URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:130507434URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:art swepub-publicationtype
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Background: Few studies have investigated the association between post-diagnosis physical activity and mortality among men diagnosed with prostate cancer. The aim of this study was to investigate the effect of physical activity after a prostate cancer diagnosis on both overall and prostate cancer-specific mortality in a large cohort. Methods: Data from 4,623 men diagnosed with localized prostate cancer 1997-2002 and followed-up until 2012 were analyzed. HRs with 95% confidence intervals (CI) were estimated using Cox proportional hazards models to examine the association between post-diagnosis recreational MET-h/d, time spent walking/bicycling, performing household work or exercising, and time to overall and prostate cancer-specific death. All models were adjusted for potential confounders. Results: During the follow-up, 561 deaths of any cause and 194 deaths from prostate cancer occurred. Statistically significantly lower overall mortality rates were found among men engaged in 5 recreationalMET-h/d (HR, 0.63; 95% CI, 0.52-0.77), walking/ bicycling 20 min/d (HR, 0.70; 95% CI, 0.57-0.86), performing householdwork > 1 h/d (HR, 0.71; 95% CI, 0.59-0.86), or exercising > 1 h/wk (HR, 0.74; 95% CI, 0.61-0.90), compared with less active men within each activity type. For prostate cancer-specific mortality, statistically significantly lower mortality rates were seen among men walking/bicycling >= 20 min/d (HR, 0.61; 95% CI, 0.43-0.87) or exercising 1 h/wk (HR, 0.68; 95% CI, 0.48-0.94). Conclusions: Higher levels of physical activity were associated with reduced rates of overall and prostate cancer-specific mortality. Impact: Our study further strengthens previous results indicating beneficial effects of physical activity on survival among men with prostate cancer. Cancer Epidemiol Biomarkers Prev; 24(1); 57-64.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Sjölander, ArvidKarolinska Institutet
(författare)
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Lagerros, Ylva TrolleKarolinska Institutet
(författare)
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Wiklund, FredrikKarolinska Institutet
(författare)
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Stattin, PärUmeå universitet,Urologi och andrologi,Umea Univ, Dept Surg & Perioperat Sci Urol & Androl, Umea, Sweden.,Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, Umeå, Sweden(Swepub:uu)parst892
(författare)
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Holmberg, ErikUniv Gothenburg, Inst Clin Sci, Dept Oncol, Sahlgrenska Acad, Gothenburg, Sweden.
(författare)
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Grönberg, HenrikKarolinska Institutet
(författare)
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Bälter, KatarinaKarolinska Institutet(Swepub:mdh)kbr01
(författare)
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Karolinska InstitutetUrologi och andrologi
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Cancer Epidemiology, Biomarkers and Prevention: AMER ASSOC CANCER RESEARCH24:1, s. 57-641055-99651538-7755
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