Sökning: onr:"swepub:oai:DiVA.org:umu-150034" > Facile Chemoenzymat...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 02556naa a2200481 4500 | |
001 | oai:DiVA.org:umu-150034 | |
003 | SwePub | |
008 | 180704s2018 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1500342 URI |
024 | 7 | a https://doi.org/10.1002/anie.2018035362 DOI |
040 | a (SwePub)umu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Shuaishuai, Wang4 aut |
245 | 1 0 | a Facile Chemoenzymatic Synthesis of O-Mannosyl Glycans |
264 | c 2018-05-18 | |
264 | 1 | b Wiley-VCH Verlagsgesellschaft,c 2018 |
338 | a print2 rdacarrier | |
520 | a Abstract O?Mannosylation is a vital protein modification involved in brain and muscle development whereas the biological relevance of O-mannosyl glycans has remained largely unknown owing to the lack of structurally defined glycoforms. An efficient scaffold synthesis/enzymatic extension (SSEE) strategy was developed to prepare such structures by combining gram-scale convergent chemical syntheses of three scaffolds and strictly controlled sequential enzymatic extension catalyzed by glycosyltransferases. In total, 45 O-mannosyl glycans were obtained, covering the majority of identified mammalian structures. Subsequent glycan microarray analysis revealed fine specificities of glycan-binding proteins and specific antisera. | |
650 | 7 | a NATURVETENSKAPx Kemix Annan kemi0 (SwePub)104992 hsv//swe |
650 | 7 | a NATURAL SCIENCESx Chemical Sciencesx Other Chemistry Topics0 (SwePub)104992 hsv//eng |
653 | a carbohydrates | |
653 | a chemoenzymatic synthesis | |
653 | a glycosylation | |
653 | a microarrays | |
653 | a O-mannosyl glycans | |
700 | 1 | a Qing, Zhang4 aut |
700 | 1 | a CongCong, Chen4 aut |
700 | 1 | a Yuxi, Guo4 aut |
700 | 1 | a Reddy, Gadi Madhusudhan4 aut |
700 | 1 | a Jin, Yu4 aut |
700 | 1 | a Ulrika, Westerlindu Umeå universitet,Kemiska institutionen4 aut0 (Swepub:umu)ulwe0024 |
700 | 1 | a Yunpeng, Liu4 aut |
700 | 1 | a Xuefeng, Cao4 aut |
700 | 1 | a G., Wang Peng4 aut |
700 | 1 | a Lei, Li4 aut |
710 | 2 | a Umeå universitetb Kemiska institutionen4 org |
773 | 0 | t Angewandte Chemie International Editiond : Wiley-VCH Verlagsgesellschaftg 57:30, s. 9268-9273q 57:30<9268-9273x 1433-7851x 1521-3773 |
856 | 4 | u https://europepmc.org/articles/pmc6097902?pdf=render |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-150034 |
856 | 4 8 | u https://doi.org/10.1002/anie.201803536 |
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