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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004274naa a2200589 4500
001oai:DiVA.org:umu-167885
003SwePub
008200205s2017 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1678852 URI
0247 a https://doi.org/10.1089/neu.2017.51942 DOI
040 a (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Huijben, Jilske A.4 aut
2451 0a Variation in Blood Transfusion and Coagulation Management in Traumatic Brain Injury at the Intensive Care Unit :b A Survey in 66 Neurotrauma Centers Participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury Study
264 1b Mary Ann Liebert,c 2017
338 a print2 rdacarrier
520 a Our aim was to describe current approaches and to quantify variability between European intensive care units (ICUs) in patients with traumatic brain injury (TBI). Therefore, we conducted a provider profiling survey as part of the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study. The ICU Questionnaire was sent to 68 centers from 20 countries across Europe and Israel. For this study, we used ICU questions focused on 1) hemoglobin target level (Hb-TL), 2) coagulation management, and 3) deep venous thromboembolism (DVT) prophylaxis. Seventy-eight participants, mostly intensivists and neurosurgeons of 66 centers, completed the ICU questionnaire. For ICU-patients, half of the centers (N = 34; 52%) had a defined Hb-TL in their protocol. For patients with TBI, 26 centers (41%) indicated an Hb-TL between 70 and 90 g/L and 38 centers (59%) above 90 g/L. To treat trauma-related hemostatic abnormalities, the use of fresh frozen plasma (N = 48; 73%) or platelets (N = 34; 52%) was most often reported, followed by the supplementation of vitamin K (N = 26; 39%). Most centers reported using DVT prophylaxis with anticoagulants frequently or always (N = 62; 94%). In the absence of hemorrhagic brain lesions, 14 centers (21%) delayed DVT prophylaxis until 72 h after trauma. If hemorrhagic brain lesions were present, the number of centers delaying DVT prophylaxis for 72 h increased to 29 (46%). Overall, a lack of consensus exists between European ICUs on blood transfusion and coagulation management. The results provide a baseline for the CENTER-TBI study, and the large between-center variation indicates multiple opportunities for comparative effectiveness research.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Neurologi0 (SwePub)302072 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Neurology0 (SwePub)302072 hsv//eng
653 a Europe
653 a coagulopathy
653 a intensive care unit
653 a transfusion
653 a traumatic brain injury
653 a neurokirurgi
653 a Neurosurgery
653 a anestesiologi
653 a Anaesthesiology
7001 a van der Jagt, Mathieu4 aut
7001 a Cnossen, Maryse C.4 aut
7001 a Kruip, Marieke J. H. A.4 aut
7001 a Haitsma, Iain K.4 aut
7001 a Stocchetti, Nino4 aut
7001 a Maas, Andrew I. R.4 aut
7001 a Menon, David K.4 aut
7001 a Ercole, Ari4 aut
7001 a Maegele, Marc4 aut
7001 a Stanworth, Simon J.4 aut
7001 a Citerio, Giuseppe4 aut
7001 a Polinder, Suzanne4 aut
7001 a Steyerberg, Ewout W.4 aut
7001 a Lingsma, Hester F.4 aut
7001 a Koskinen, Lars-Owe D.,c Professor,d 1955-u Center-TBI Investigators and Participants4 ctb0 (Swepub:umu)lako0002
7001 a Brorsson, Camillau Umeå universitet,Anestesiologi och intensivvård0 (Swepub:umu)brca0001
7102 a Center-TBI Investigators and Participantsb Anestesiologi och intensivvård4 org
7730 t Journal of Neurotraumad : Mary Ann Liebertg 35:2, s. 323-332q 35:2<323-332x 0897-7151x 1557-9042
8564 u https://repository.uantwerpen.be/docman/irua/404562/147702_2019_01_15.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-167885
8564 8u https://doi.org/10.1089/neu.2017.5194

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