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  • Malm, Jan,Professor,1957-Umeå universitet,Institutionen för farmakologi och klinisk neurovetenskap (författare)

Influence of comorbidities in idiopathic normal pressure hydrocephalus - research and clinical care : A report of the ISHCSF task force on comorbidities in INPH

  • Artikel/kapitelEngelska2013

Förlag, utgivningsår, omfång ...

  • BioMed Central (BMC),2013
  • electronicrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:umu-202175
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-202175URI
  • https://doi.org/10.1186/2045-8118-10-22DOI
  • https://gup.ub.gu.se/publication/179163URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Idiopathic normal pressure hydrocephalus (INPH) is a syndrome of ventriculomegaly, gait impairment, cognitive decline and incontinence that occurs in an elderly population prone to many types of comorbidities. Identification of the comorbidities is thus an important part of the clinical management of INPH patients. In 2011, a task force was appointed by the International Society for Hydrocephalus and Cerebrospinal Fluid Disorders (ISHCSF) with the objective to compile an evidence-based expert analysis of what we know and what we need to know regarding comorbidities in INPH. This article is the final report of the task force. The expert panel conducted a comprehensive review of the literature. After weighing the evidence, the various proposals were discussed and the final document was approved by all the task force members and represents a consensus of expert opinions. Recommendations regarding the following topics are given: I. Musculoskeletal conditions; II. Urinary problems; III. Vascular disease including risk factors, Binswanger disease, and white matter hyperintensities; IV. Mild cognitive impairment and Alzheimer disease including biopsies; V. Other dementias (frontotemporal dementia, Lewy body, Parkinson); VI. Psychiatric and behavioral disorders; VII. Brain imaging; VIII. How to investigate and quantify. The task force concluded that comorbidity can be an important predictor of prognosis and post-operative outcome in INPH. Reported differences in outcomes among various INPH cohorts may be partly explained by variation in the rate and types of comorbidities at different hydrocephalus centers. Identification of comorbidities should thus be a central part of the clinical management of INPH where a detailed history, physical examination, and targeted investigations are the basis for diagnosis and grading. Future INPH research should focus on the contribution of comorbidity to overall morbidity, mortality and long-term outcomes.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Graff-Radford, Neill R.Department of Neurology, Mayo Clinic Jacksonville, Jacksonville, FL, United States (författare)
  • Ishikawa, MasatsuneNormal Pressure Hydrocephalus Center, Otowa Hospital, Kyoto, Japan (författare)
  • Kristensen, BoDepartment of Neurology, Aalborg University, Aalborg, Denmark (författare)
  • Leinonen, VilleDepartment of Neurosurgery, KUH NeuroCenter, Kuopio University Hospital and Institute of Clinical Medicine, Kuopio, Finland; Department of Neurosurgery, University of Eastern Finland, Kuopio, Finland (författare)
  • Mori, EtsuroDepartment of Behavioral Neurology and Cognitive Neuroscience, Tohoku University, Graduate School of Medicine, Sendai, Japan (författare)
  • Owler, Brian K.Department of Surgery, University of Sydney, Sydney, Australia (författare)
  • Tullberg, Mats,1965Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap och rehabilitering,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation(Swepub:gu)xtumat (författare)
  • Williams, Michael A.Sandra and Malcolm Berman Brain, Spine Institute of Sinai Hospital, Baltimore, United States (författare)
  • Relkin, Norman R.Department of Neurology and Neuroscience, Weill Cornell Medical College, New York, United States (författare)
  • Umeå universitetInstitutionen för farmakologi och klinisk neurovetenskap (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Fluids and Barriers of the CNS: BioMed Central (BMC)10:12045-8118

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