Sökning: onr:"swepub:oai:DiVA.org:umu-202341" > Circulating vitamin...
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001 | oai:DiVA.org:umu-202341 | |
003 | SwePub | |
008 | 230112s2023 | |||||||||||000 ||eng| | |
009 | oai:lup.lub.lu.se:6c20929c-6522-4b38-819b-1faed3270955 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-2023412 URI |
024 | 7 | a https://doi.org/10.1007/s10654-022-00921-12 DOI |
024 | 7 | a https://lup.lub.lu.se/record/6c20929c-6522-4b38-819b-1faed32709552 URI |
040 | a (SwePub)umud (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Visvanathan, Kalau Departments of Epidemiology and Oncology, Johns Hopkins Bloomberg School of Public Health and Kimmel Cancer Center, MD, Baltimore, United States4 aut |
245 | 1 0 | a Circulating vitamin D and breast cancer risk :b an international pooling project of 17 cohorts |
264 | c 2023-01-03 | |
264 | 1 | b Springer Science+Business Media B.V.c 2023 |
338 | a print2 rdacarrier | |
520 | a Laboratory and animal research support a protective role for vitamin D in breast carcinogenesis, but epidemiologic studies have been inconclusive. To examine comprehensively the relationship of circulating 25-hydroxyvitamin D [25(OH)D] to subsequent breast cancer incidence, we harmonized and pooled participant-level data from 10 U.S. and 7 European prospective cohorts. Included were 10,484 invasive breast cancer cases and 12,953 matched controls. Median age (interdecile range) was 57 (42–68) years at blood collection and 63 (49–75) years at breast cancer diagnosis. Prediagnostic circulating 25(OH)D was either newly measured using a widely accepted immunoassay and laboratory or, if previously measured by the cohort, calibrated to this assay to permit using a common metric. Study-specific relative risks (RRs) for season-standardized 25(OH)D concentrations were estimated by conditional logistic regression and combined by random-effects models. Circulating 25(OH)D increased from a median of 22.6 nmol/L in consortium-wide decile 1 to 93.2 nmol/L in decile 10. Breast cancer risk in each decile was not statistically significantly different from risk in decile 5 in models adjusted for breast cancer risk factors, and no trend was apparent (P-trend = 0.64). Compared to women with sufficient 25(OH)D based on Institute of Medicine guidelines (50– < 62.5 nmol/L), RRs were not statistically significantly different at either low concentrations (< 20 nmol/L, 3% of controls) or high concentrations (100– < 125 nmol/L, 3% of controls; ≥ 125 nmol/L, 0.7% of controls). RR per 25 nmol/L increase in 25(OH)D was 0.99 [95% confidence intervaI (CI) 0.95–1.03]. Associations remained null across subgroups, including those defined by body mass index, physical activity, latitude, and season of blood collection. Although none of the associations by tumor characteristics reached statistical significance, suggestive inverse associations were seen for distant and triple negative tumors. Circulating 25(OH)D, comparably measured in 17 international cohorts and season-standardized, was not related to subsequent incidence of invasive breast cancer over a broad range in vitamin D status. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
653 | a 25-Hydroxyvitamin D | |
653 | a Biomarker | |
653 | a Breast cancer | |
653 | a Calibration | |
653 | a Pooled analysis | |
653 | a Prospective cohort study | |
653 | a Vitamin D | |
653 | a 25-Hydroxyvitamin D | |
653 | a Biomarker | |
653 | a Breast cancer | |
653 | a Calibration | |
653 | a Pooled analysis | |
653 | a Prospective cohort study | |
653 | a Vitamin D | |
700 | 1 | a Mondul, Alison M.u Department of Epidemiology, University of Michigan School of Public Health, MI, Ann Arbor, United States4 aut |
700 | 1 | a Zeleniuch-Jacquotte, Anneu Departments of Population Health and Environmental Medicine, New York University Grossman School of Medicine, NY, New York, United States4 aut |
700 | 1 | a Wang, Molinu Department of Biostatistics, Harvard T.H. Chan School of Public Health, MA, Boston, United States; Department of Epidemiology, Harvard T.H. Chan School of Public Health, MA, Boston, United States; Channing Division of Network Medicine, Department of Medicine, Harvard Medical School, MA, Boston, United States4 aut |
700 | 1 | a Gail, Mitchell H.u Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, MD, Bethesda, United States4 aut |
700 | 1 | a Yaun, Shiaw-Shyuanu Department of Nutrition, Harvard T.H. Chan School of Public Health, MA, Boston, United States4 aut |
700 | 1 | a Weinstein, Stephanie J.u Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, MD, Bethesda, United States4 aut |
700 | 1 | a McCullough, Marjorie L.u Department of Population Science, American Cancer Society, GA, Atlanta, United States4 aut |
700 | 1 | a Eliassen, A. Heatheru Department of Epidemiology, Harvard T.H. Chan School of Public Health, MA, Boston, United States; Channing Division of Network Medicine, Department of Medicine, Harvard Medical School, MA, Boston, United States; Department of Nutrition, Harvard T.H. Chan School of Public Health, MA, Boston, United States4 aut |
700 | 1 | a Cook, Nancy R.u Department of Epidemiology, Harvard T.H. Chan School of Public Health, MA, Boston, United States; Division of Preventive Medicine, Brigham and Women’s Hospital, Harvard Medical School, MA, Boston, United States4 aut |
700 | 1 | a Agnoli, Claudiau Epidemiology and Prevention Unit, IRCCS National Cancer Institute Foundation, Milan, Italy4 aut |
700 | 1 | a Almquist, Martinu Lund University,Lunds universitet,Kirurgi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Surgery (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital4 aut0 (Swepub:lu)kir-mal |
700 | 1 | a Black, Amandau Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, MD, Bethesda, United States4 aut |
700 | 1 | a Buring, Julie E.u Department of Epidemiology, Harvard T.H. Chan School of Public Health, MA, Boston, United States; Division of Preventive Medicine, Brigham and Women’s Hospital, Harvard Medical School, MA, Boston, United States4 aut |
700 | 1 | a Chen, Chuu Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, WA, Seattle, United States4 aut |
700 | 1 | a Chen, Yuu Departments of Population Health and Environmental Medicine, New York University Grossman School of Medicine, NY, New York, United States4 aut |
700 | 1 | a Clendenen, Tessu Departments of Population Health and Environmental Medicine, New York University Grossman School of Medicine, NY, New York, United States4 aut |
700 | 1 | a Dossus, Laureu Nutrition and Metabolism Branch, International Agency for Research on Cancer, World Health Organization, Lyon, France4 aut |
700 | 1 | a Fedirko, Veronikau Department of Epidemiology, Rollins School of Public Health and Winship Cancer Institute, Emory University, GA, Atlanta, United States4 aut |
700 | 1 | a Gierach, Gretchen L.u Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, MD, Bethesda, United States4 aut |
700 | 1 | a Giovannucci, Edward L.u Department of Epidemiology, Harvard T.H. Chan School of Public Health, MA, Boston, United States; Channing Division of Network Medicine, Department of Medicine, Harvard Medical School, MA, Boston, United States; Department of Nutrition, Harvard T.H. Chan School of Public Health, MA, Boston, United States4 aut |
700 | 1 | a Goodman, Gary E.u Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, WA, Seattle, United States4 aut |
700 | 1 | a Goodman, Marc T.u Cancer Prevention and Control Research Program, Cedars Sinai Samuel Oschin Comprehensive Cancer Institute, CA, Los Angeles, United States4 aut |
700 | 1 | a Guénel, Pascalu Center for Research in Epidemiology and Population Health (CESP), French National Institute of Health and Medical Research (INSERM), University Paris-Saclay, Villejuif, France4 aut |
700 | 1 | a Hallmans, Göran,d 1947-u Umeå universitet,Institutionen för folkhälsa och klinisk medicin4 aut0 (Swepub:umu)goha0001 |
700 | 1 | a Hankinson, Susan E.u Department of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts Amherst, MA, Amherst, United States4 aut |
700 | 1 | a Horst, Ronald L.u Heartland Assays, LLC, IA, Ames, United States4 aut |
700 | 1 | a Hou, Taou Department of Nutrition, Harvard T.H. Chan School of Public Health, MA, Boston, United States4 aut |
700 | 1 | a Huang, Wen-Yiu Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, MD, Bethesda, United States4 aut |
700 | 1 | a Jones, Michael E.u Division of Genetics and Epidemiology, The Institute of Cancer Research, London, United Kingdom4 aut |
700 | 1 | a Joshu, Corrine E.u Departments of Epidemiology and Oncology, Johns Hopkins Bloomberg School of Public Health and Kimmel Cancer Center, MD, Baltimore, United States4 aut |
700 | 1 | a Kaaks, Rudolfu Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany4 aut |
700 | 1 | a Krogh, Vittoriou Epidemiology and Prevention Unit, IRCCS National Cancer Institute Foundation, Milan, Italy4 aut |
700 | 1 | a Kühn, Tilmanu Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Institute for Global Food Security, Queen’s University, Belfast, United Kingdom4 aut |
700 | 1 | a Kvaskoff, Marinau Center for Research in Epidemiology and Population Health (CESP), French National Institute of Health and Medical Research (INSERM), University Paris-Saclay, Villejuif, France4 aut |
700 | 1 | a Lee, I-Minu Department of Epidemiology, Harvard T.H. Chan School of Public Health, MA, Boston, United States; Division of Preventive Medicine, Brigham and Women’s Hospital, Harvard Medical School, MA, Boston, United States4 aut |
700 | 1 | a Mahamat-Saleh, Yahyau Center for Research in Epidemiology and Population Health (CESP), French National Institute of Health and Medical Research (INSERM), University Paris-Saclay, Villejuif, France4 aut |
700 | 1 | a Malm, J.u Lund University,Lunds universitet,Institutionen för translationell medicin,Medicinska fakulteten,Department of Translational Medicine,Faculty of Medicine4 aut0 (Swepub:lu)klke-jma |
700 | 1 | a Manjer, J.u Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Surgery,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments4 aut0 (Swepub:lu)smi-jma |
700 | 1 | a Maskarinec, Gertraudu Cancer Epidemiology Program, University of Hawai’i Cancer Center, HI, Honolulu, United States4 aut |
700 | 1 | a Millen, Amy E.u Department of Epidemiology and Environmental Health, University at Buffalo, NY, Buffalo, United States4 aut |
700 | 1 | a Mukhtar, Toqir K.u Department of Primary Care and Public Health, Imperial College, London, United Kingdom; Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom4 aut |
700 | 1 | a Neuhouser, Marian L.u Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, WA, Seattle, United States4 aut |
700 | 1 | a Robsahm, Trude E.u Cancer Registry of Norway, Institute of Population-Based Cancer Research, Oslo, Norway4 aut |
700 | 1 | a Schoemaker, Minouk J.u Division of Genetics and Epidemiology, The Institute of Cancer Research, London, United Kingdom4 aut |
700 | 1 | a Sieri, Sabinau Epidemiology and Prevention Unit, IRCCS National Cancer Institute Foundation, Milan, Italy4 aut |
700 | 1 | a Sund, Malinu Umeå universitet,Institutionen för kirurgisk och perioperativ vetenskap4 aut0 (Swepub:umu)masu0021 |
700 | 1 | a Swerdlow, Anthony J.u Division of Genetics and Epidemiology, The Institute of Cancer Research, London, United Kingdom; Division of Breast Cancer Research, The Institute of Cancer Research, London, United Kingdom4 aut |
700 | 1 | a Thomson, Cynthia A.u Department of Health Promotion Sciences, Mel and Enid Zuckerman College of Public Health, University of Arizona and University of Arizona Cancer Center, AZ, Tucson, United States4 aut |
700 | 1 | a Ursin, Giskeu Cancer Registry of Norway, Institute of Population-Based Cancer Research, Oslo, Norway; Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway4 aut |
700 | 1 | a Wactawski-Wende, Jeanu Department of Epidemiology and Environmental Health, University at Buffalo, NY, Buffalo, United States4 aut |
700 | 1 | a Wang, Yingu Department of Population Science, American Cancer Society, GA, Atlanta, United States4 aut |
700 | 1 | a Wilkens, Lynne R.u Population Sciences in the Pacific, University of Hawai’i Cancer Center, HI, Honolulu, United States4 aut |
700 | 1 | a Wu, Yujieu Department of Biostatistics, Harvard T.H. Chan School of Public Health, MA, Boston, United States4 aut |
700 | 1 | a Zoltick, Emilieu Department of Population Medicine, Harvard Medical School, MA, Boston, United States4 aut |
700 | 1 | a Willett, Walter C.u Department of Epidemiology, Harvard T.H. Chan School of Public Health, MA, Boston, United States; Department of Nutrition, Harvard T.H. Chan School of Public Health, MA, Boston, United States4 aut |
700 | 1 | a Smith-Warner, Stephanie A.u Department of Epidemiology, Harvard T.H. Chan School of Public Health, MA, Boston, United States; Department of Nutrition, Harvard T.H. Chan School of Public Health, MA, Boston, United States4 aut |
700 | 1 | a Ziegler, Regina G.u Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, MD, Bethesda, United States,National Cancer Institute, NCI4 aut |
710 | 2 | a Departments of Epidemiology and Oncology, Johns Hopkins Bloomberg School of Public Health and Kimmel Cancer Center, MD, Baltimore, United Statesb Department of Epidemiology, University of Michigan School of Public Health, MI, Ann Arbor, United States4 org |
710 | 2 | a et al. |
773 | 0 | t European Journal of Epidemiologyd : Springer Science+Business Media B.V.g 38, s. 11-29q 38<11-29x 0393-2990x 1573-7284 |
856 | 4 | u http://dx.doi.org/10.1007/s10654-022-00921-1y FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-202341 |
856 | 4 8 | u https://doi.org/10.1007/s10654-022-00921-1 |
856 | 4 8 | u https://lup.lub.lu.se/record/6c20929c-6522-4b38-819b-1faed3270955 |
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