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Improved procedure ...
Improved procedure for the enantioselective synthesis of dihydrooxazolo and dihydrothiazolo ring-fused 2-pyridones
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- Chorell, Erik, 1980- (författare)
- Umeå universitet,Kemiska institutionen,Fredrik Almqvist
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- Edvinsson, Sofie (författare)
- Umeå universitet,Kemiska institutionen
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- Almqvist, Fredrik (författare)
- Umeå universitet,Kemiska institutionen
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(creator_code:org_t)
- Elsevier Ltd, 2010
- 2010
- Engelska.
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Ingår i: Tetrahedron Letters. - : Elsevier Ltd. - 0040-4039 .- 1359-8562. ; 51:18, s. 2461-2463
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Improved procedures to synthesize enantioselectively analogues of a peptidomimetic scaffold with high biological relevance have been developed. Experimental design led to a general method for the preparation of dihydrooxazolo ring-fused 2-pyridones in good yields and high enantiomeric purity. The knowledge gained from this was also used to improve the microwave-accelerated synthesis of dihydrothiazolo ring-fused 2-pyridones to give complete stereo retention and high yields.
Nyckelord
- 2-Pyridone
- PPTS
- Peptidomimetic
- Enantioselective
- Pilicide
- Curlicide
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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