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- Häggmark, SörenUmeå universitet,Anestesiologi och intensivvård (author)
ST-segment deviations during pacing-induced increased heart rate in patients without coronary artery disease.
- Article/chapterEnglish2005
Publisher, publication year, extent ...
- 2005
- electronicrdacarrier
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- LIBRIS-ID:oai:DiVA.org:umu-6814
- https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-6814URI
- https://doi.org/10.1111/j.1475-097X.2005.00613.xDOI
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- Language:English
- Summary in:English
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- INTRODUCTION: In order to interpret ST-segment changes as an indicator of ischemia in patients with higher heart rates (HRs), the relation between ST-segment levels and HR needs to be well defined in subjects without coronary artery disease. METHODS: Eighteen patients with normal ECGs in the catheterization laboratory, after radiofrequency ablation of AV nodal re-entry tachycardia or an accessory pathway were included. Computerized online vectorcardiography (VCG) was performed during step-wise atrial pacing-induced increases in HR up to 150 beats min(-1) (bpm). The ST-vector magnitude (ST-VM) and the relative ST change vector magnitude (STC-VM) were analysed at the J point, J + 20 and J + 60 ms. RESULTS: There was no divergence in the course of ST-VM or STC-VM based on J point + 0, 20, or 60 ms during increasing HR. The STC-VM mean values increased progressively during increases in HR above 100 bpm, with an average increase in STC-VM of 15-20 microV per 10 bpm increases in HR. The ST-VM response during HR increases showed a heterogeneous and unpredictable pattern. CONCLUSION: The STC-VM increases linearly with rising HRs above 100 bpm. The STC-VM can exceed widely recognized ischemic thresholds during higher HRs in the absence of ischemia. The choice of J point time to ST-VM measurements as tested here is not important for the STC-VM relation to HR at these HR levels. Further clinical testing is needed to improve the diagnostic specificity of STC-VM measurements during increased HRs.
Subject headings and genre
- Adult
- Arrhythmias; Cardiac/*diagnosis/*physiopathology/therapy
- Cardiac Pacing; Artificial/*methods
- Coronary Disease/diagnosis/physiopathology/therapy
- Female
- Heart Rate
- Humans
- Male
- Middle Aged
- Statistics as Topic
- Vectorcardiography/*methods
Added entries (persons, corporate bodies, meetings, titles ...)
- Haney, Michael FUmeå universitet,Anestesiologi och intensivvård(Swepub:umu)milhay96 (author)
- Jensen, Steen MUmeå universitet,Institutionen för folkhälsa och klinisk medicin (author)
- Johansson, GöranUmeå universitet,Anestesiologi och intensivvård(Swepub:umu)gojo0001 (author)
- Näslund, UlfUmeå universitet,Institutionen för folkhälsa och klinisk medicin(Swepub:umu)ulna0002 (author)
- Umeå universitetAnestesiologi och intensivvård (creator_code:org_t)
Related titles
- In:Clinical Physiology and Functional Imaging25:4, s. 246-5221475-09611475-097X
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