Search: onr:"swepub:oai:DiVA.org:umu-84232" >
Word-level intellig...
Word-level intelligibility after caudal zona incerta stimulation for Parkinson’s disease
-
- Louise, Johansson (author)
- Umeå universitet,Logopedi
-
- Sofia, Möller (author)
- Umeå universitet,Logopedi
-
- Olofsson, Katarina (author)
- Umeå universitet,Öron- näs- och halssjukdomar
-
show more...
-
- Linder, Jan (author)
- Umeå universitet,Neurologi
-
- Nordh, Erik (author)
- Umeå universitet,Neurologi,Klinisk neurofysiologi
-
- Blomstedt, Patric (author)
- Umeå universitet,Neurokirurgi
-
- Doorn, Jan van (author)
- Umeå universitet,Logopedi
-
- Karlsson, Fredrik, 1975- (author)
- Umeå universitet,Institutionen för språkstudier,Logopedi
-
show less...
-
(creator_code:org_t)
- 2013-12-17
- 2014
- English.
-
In: Acta Neurologica Scandinavica. - : Wiley-Blackwell. - 0001-6314 .- 1600-0404. ; 130:1, s. 27-33
- Related links:
-
https://urn.kb.se/re...
-
show more...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- Objectives – To investigate the effect of caudal zona incerta-deep brain stimulation (cZi-DBS) on word-level speech intelligibility in patients with Parkinson’s disease, under both an optimal listening condition and a simulated more naturalistic listening condition.Materials and methods – Spoken single words were extracted from read samples collected from 10 bilaterally implanted patients with PD pre- and post-cZi-DBS. Intelligibility was assessed through a transcription task performed by 32 naive listeners under two listening conditions: (i) with low-amplitude conversational speech added as background and (ii) with no added background noise. The listeners′ responses were scored in terms of agreement with the intended words.Results – Post-operatively, the total intelligibility score was significantly lower when cZi stimulation was switched on compared with off, for both listening conditions (with and without added background noise). Intelligibility was also significantly lower on stimulation compared with preoperative recordings, but only when assessed in the listening condition without background noise. The listening condition with added background noise resulted in significantly lower intelligibility scores compared with the no added noise condition for all stimulation conditions.Conclusions – The results of this study indicate that cZi-DBS in patients with PD can be detrimental to word-level speech intelligibility.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Annan medicin och hälsovetenskap -- Övrig annan medicin och hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Other Medical and Health Sciences -- Other Medical and Health Sciences not elsewhere specified (hsv//eng)
Keyword
- caudal zona incerta
- deep brain stimulation
- Parkinson's disease
- speech intelligibility
- neurologi
- Neurology
- Linguistics
- lingvistik
- neurokirurgi
- Neurosurgery
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database