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Sökning: onr:"swepub:oai:DiVA.org:uu-11968" > A new model for low...

  • Devenney, IreneLinköpings universitet,Pediatrik,Hälsouniversitetet (författare)

A new model for low-dose food challenge in children with allergy to milk or egg.

  • Artikel/kapitelEngelska2006

Förlag, utgivningsår, omfång ...

  • Wiley,2006
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:uu-11968
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-11968URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-14561URI
  • https://doi.org/10.1080/08035250500516672DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Division of Paediatrics, Department of Molecular and Clinical Medicine, Faculty of Health Sciences, Linköping University, Linköping, and Paediatric Clinic, County Hospital Ryhov, Fonköping, Sweden. irene.devenney@lio.seBACKGROUND: Atopic eczema and food allergy are common in early childhood. Children seem to gradually develop tolerance to milk and egg, and it is a relief for families when their child can tolerate small amounts of these basic foods, even if larger doses may still cause symptoms. AIM: To develop a model for low-dose oral food challenge, facilitating re-/introduction of milk or egg. METHODS: In 39 children sensitized to milk and/or egg, we performed 52 challenges using a new standardized model for low-dose oral food challenge. The recipes were validated for blinding with sensorial tests. RESULTS: Four children challenged to milk had a positive challenge outcome. There were no significant differences with respect to family history, associated atopic manifestations, nutritional supply, eczema severity, or skin-prick test compared with the non-reacting children, but total and specific IgE values were significantly higher. All but two of the non-reacting children were able to introduce milk and egg into their diet without problems. CONCLUSION: We report recipes and a protocol to be used for standardized open and double-blind placebo-controlled low-dose food challenge in young children, enabling the introduction of small amounts of egg and milk into the diet during tolerance development.

Ämnesord och genrebeteckningar

  • Child; Preschool
  • Cookery/*methods
  • Double-Blind Method
  • Egg Hypersensitivity/*therapy
  • Female
  • Humans
  • Infant
  • Male
  • Milk Hypersensitivity/*therapy
  • Prospective Studies
  • Taste
  • Treatment Outcome
  • MEDICINE

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Norrman, GunillaLinköpings universitet,Uppsala universitet,Centrum för klinisk forskning, Gävleborg,Pediatrik,Hälsouniversitetet(Swepub:liu)gunjo87 (författare)
  • Oldaeus, GöranPaediatric Clinic, County Hospital Ryhov, Jönköping, Sweden(Swepub:liu)gorol11 (författare)
  • Strömberg, LeifPaediatric Clinic, Vrinnevi Hospital, Norrköping, Sweden (författare)
  • Fälth-Magnusson, KarinLinköpings universitet,Pediatrik,Hälsouniversitetet(Swepub:liu)karfa12 (författare)
  • Linköpings universitetPediatrik (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Acta Paediatr: Wiley95:9, s. 1133-90803-52531651-2227

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