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Acquired hemophagoc...
Acquired hemophagocytic lymphohistiocytosis associated with multiple myeloma
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- Machaczka, Maciej (author)
- Karolinska Institutet
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Vaktnäs, Johan (author)
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Klimkowska, Monika (author)
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- Nahi, Hareth (author)
- Karolinska Institutet
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- Hägglund, Hans (author)
- Hematology Center Karolinska, M54, Karolinska University Hospital Huddinge, Stockholm, Sweden
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(creator_code:org_t)
- 2010-04-01
- 2011
- English.
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In: Medical Oncology. - : Springer Science and Business Media LLC. - 1357-0560 .- 1559-131X. ; 28:2, s. 539-543
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Subject headings
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- Acquired or secondary hemophagocytic lymphohistiocytosis (sHLH) is a life-threatening hyperinflammation syndrome caused mostly by various infectious agents, autoimmune disorders or malignancy. So far, only anecdotal cases of sHLH associated with multiple myeloma have been published. We provide a review of all these reports and include a previously not published case of myeloma-associated sHLH in a 59-year-old male with complex partial epilepsy. Due to aggressive course of sHLH, increased awareness is indicated in all patients with malignancies which develop unremitting fever, cytopenia and splenomegaly. Early diagnosis and immediate introduction of adequate therapy is crucial for the outcome of HLH.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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